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Description Entry page for Effector - 'GRK6-Homo sapiens'
FamilySer Thr protein kinases
Sub-FamilyG protein coupled receptor kinases
TypeGRK6
Cross References:
References
UniProtP43250 | O60541 | Q13652
EMBLL16862 | AF040751 | AF040752 | BC009277 | U00686
InterProIPR000961 | IPR000239 | IPR000719 | IPR017441 | IPR000342 | IPR017442 | IPR008271 | IPR002290
PRODOMPD000001
GENEID2870
MIM600869
PRINTSPR00717
PFAMPF00069 | PF00615
Details:
Details
NameGRK6-Homo sapiens
DescriptionRecName: Full=G protein-coupled receptor kinase 6; EC=2.7.11.16;AltName: Full=G protein-coupled receptor kinase GRK6
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGRK6 | GPRK
FunctionSpecifically phosphorylates the activated forms of Gs protein-coupled receptors
Fragment0
Sequence
MELENIVANTVLLKAREGGGGNRKGKSKKWRQMLQFPHISQCEELRLSLERDYHSLCERQ
PIGRLLFREFCATRPELSRCVAFLDGVAEYEVTPDDKRKACGRQLTQNFLSHTGPDLIPE
VPRQLVTNCTQRLEQGPCKDLFQELTRLTHEYLSVAPFADYLDSIYFNRFLQWKWLERQP
VTKNTFRQYRVLGKGGFGEVCACQVRATGKMYACKKLEKKRIKKRKGEAMALNEKQILEK
VNSRFVVSLAYAYETKDALCLVLTLMNGGDLKFHIYHMGQAGFPEARAVFYAAEICCGLE
DLHRERIVYRDLKPENILLDDHGHIRISDLGLAVHVPEGQTIKGRVGTVGYMAPEVVKNE
RYTFSPDWWALGCLLYEMIAGQSPFQQRKKKIKREEVERLVKEVPEEYSERFSPQARSLC
SQLLCKDPAERLGCRGGSAREVKEHPLFKKLNFKRLGAGMLEPPFKPDPQAIYCKDVLDI
EQFSTVKGVELEPTDQDFYQKFATGSVPIPWQNEMVETECFQELNVFGLDGSVPPDLDWK
GQPPAPPKKGLLQRLFSRQDCCGNCSDSEEELPTRL
Interacting with G-proteins:
G-proteins
NoNameRegulationPubMed
1Galpha-15_Homo sapiensStimulation14654303
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level