| Description |
Entry page for GPCR - 'HISTAMINE RECEPTORS_H1_Homo sapiens'
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Cross References: |
| References |
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Details: |
| Details |
| Name | HISTAMINE RECEPTORS_H1_Homo sapiens |
| Description | RecName: Full=Histamine H1 receptor |
| Species | Homo sapiens |
| Common Name | Human |
| NCBI Taxonomy | 9606 |
| Gene | HRH |
| Function | In peripheral tissues, the H1 subclass of histamines receptors mediates the contraction of smooth muscles, increase ins capillary permeability due to contraction of terminal venules, ands catecholamine release from adrenal medulla, as well as mediatings neurotransmission in the central nervous system |
| Fragment | 0 |
| Sequence | MSLPNSSCLLEDKMCEGNKTTMASPQLMPLVVVLSTICLVTVGLNLLVLYAVRSERKLHT
VGNLYIVSLSVADLIVGAVVMPMNILYLLMSKWSLGRPLCLFWLSMDYVASTASIFSVFI
LCIDRYRSVQQPLRYLKYRTKTRASATILGAWFLSFLWVIPILGWNHFMQQTSVRREDKC
ETDFYDVTWFKVMTAIINFYLPTLLMLWFYAKIYKAVRQHCQHRELINRSLPSFSEIKLR
PENPKGDAKKPGKESPWEVLKRKPKDAGGGSVLKSPSQTPKEMKSPVVFSQEDDREVDKL
YCFPLDIVHMQAAAEGSSRDYVAVNRSHGQLKTDEQGLNTHGASEISEDQMLGDSQSFSR
TDSDTTTETAPGKGKLRSGSNTGLDYIKFTWKRLRSHSRQYVSGLHMNRERKAAKQLGFI
MAAFILCWIPYFIFFMVIAFCKNCCNEHLHMFTIWLGYINSTLNPLIYPLCNENFKKTFK
RILHIRS
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Interacting with G-proteins: |
| G-proteins |
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| GPCR, G-protein, Effector interaction |
Visualizaton of GPCR, G-protein, Effector interaction at protein level
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