Human-gpDB    A database of human GPCRs, G-proteins, Effectors and their interactions

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	Summary sheet information for Effector 'Src tyrosine kinase-Homo sapiens-1'
Name	Src tyrosine kinase-Homo sapiens-1
Description	RecName: Full=Tyrosine-protein kinase CSK; EC=2.7.10.2;AltName: Full=C-SRC kinase;AltName: Full=Protein-tyrosine kinase CYL
Class
Family	Tyr protein kinases
Sub_family	Tyr protein kinases
type	Src tyrosine kinase
Protein features link	Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction	Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes	Gene Location: Chromosome : 15 Gene Start : 72861768 Gene End : 72882557 Ensembl Contig View Ensembl Genes: ENSG00000103653 EMBL: EMBL ID    Description AK223626    Homo sapiens mRNA for c-src tyrosine kinase variant, clone: FCC134G03. AK290531    Homo sapiens cDNA FLJ78579 complete cds, highly similar to Homo sapiens c-src tyrosine kinase (CSK), mRNA. AK312669    Homo sapiens cDNA, FLJ93062, Homo sapiens c-src tyrosine kinase (CSK), mRNA. BC104847    Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:132507 IMAGE:8143850), complete cds. BC104875    Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:132535 IMAGE:8143878), complete cds. BC106073    Homo sapiens c-src tyrosine kinase, mRNA (cDNA clone MGC:117393 IMAGE:6526810), complete cds. CH471136    Homo sapiens 211000035841687 genomic scaffold, whole genome shotgun sequence. CR541960    Homo sapiens full open reading frame cDNA clone RZPDo834E0634D for gene CSK, c-src tyrosine kinase; complete cds, without stopcodon. DQ075211    Homo sapiens c-src tyrosine kinase (CSK) gene, complete cds. X59932    Human mRNA for C-SRC-kinase X60114    H.sapiens cyl mRNA for cytoplasmic tryrosine kinase X74765    Homo sapiens CSK gene for protein tyrosine kinase EntrezGene: ID    Description CSK    c-src tyrosine kinase RefSeq DNA: ID    Description NM_001127190    Homo sapiens c-src tyrosine kinase (CSK), transcript variant 2, mRNA. NM_004383    Homo sapiens c-src tyrosine kinase (CSK), transcript variant 1, mRNA. UniGene: ID    Description Hs.77793    CSK mRNA for c-src tyrosine kinase, complete cds, clone: FLJ08127AAAN
Proteins	Ensembl Proteins: ENSP00000220003 Entrez Proteins: AAI04848.1; AAI04876.1; AAI06074.1; AAY57329.1; BAD97346.1; BAF83220.1; BAG35551.1; CAA42556.1; CAA42713.1; CAB58562.1; CAG46758.1; EAW99311.1 RefSeq Proteins: ID    Description NP_001120662    c-src tyrosine kinase [Homo sapiens]. NP_004374    c-src tyrosine kinase [Homo sapiens]. UniProt: ID    Description A8K3B6    SubName: Full=cDNA FLJ78579, highly similar to Homo sapiens c-src tyrosine kinase (CSK), mRNA; B2R6Q4    SubName: Full=cDNA FLJ45770 fis, clone NETRP2002197, highly similar to Tyrosine-protein kinase CSK (EC 2.7.10.2); SubName: Full=C-src tyrosine kinase, isoform CRA_a; SubName: Full=cDNA, FLJ93062, Homo sapiens c-src tyrosine kinase (CSK), mRNA; Q53EL3    SubName: Full=C-src tyrosine kinase variant; Flags: Fragment; P41240    RecName: Full=Tyrosine-protein kinase CSK; EC=2.7.10.2; AltName: Full=C-SRC kinase; AltName: Full=Protein-tyrosine kinase CYL;
Domains	SMART: - Hyperlink to SMART; - Hyperlink to ENSEMBL       Src tyrosine kinase-Homo sapiens-1     InterPro: ID    Name IPR000719    Prot_kinase_core IPR015778    Tyrosine_Protein_Kinase_Csk IPR017441    Protein_kinase_ATP_bd_CS IPR001452    SH3_domain IPR008266    Tyr_pkinase_AS IPR000980    SH2 IPR001245    Tyr_pkinase Pfam: ID    Description SH2    SH2 domain SH3_1    SH3 domain Pkinase_Tyr    Protein tyrosine kinase
Structure	PDB: ID 1BYG 1CSK 3D7T 3D7U HSSP: ID    Description 1a07    COMPLEX (TRANSFERASE/PEPTIDE) 1a08    COMPLEX (TRANSFERASE/PEPTIDE) 1a09    COMPLEX (TRANSFERASE/PEPTIDE) 1a1a    COMPLEX (TRANSFERASE/PEPTIDE) 1a1b    COMPLEX (TRANSFERASE/PEPTIDE) 1a1c    COMPLEX (TRANSFERASE/PEPTIDE) 1a1e    COMPLEX (TRANSFERASE/PEPTIDE) 1a81    COMPLEX (TRANSFERASE/PEPTIDE) 1ab2    TRANSFERASE(PHOSPHOTRANSFERASE) 1ad5    TYROSINE-PROTEIN KINASE 1agw    PROTEIN KINASE 1aot    COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN) 1aou    COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN) 1aww    TRANSFERASE 1awx    TRANSFERASE 1aya    HYDROLASE(SH2 DOMAIN) 1ayb    HYDROLASE(SH2 DOMAIN) 1ayc    HYDROLASE(SH2 DOMAIN) 1ayd    HYDROLASE(SH2 DOMAIN) 1aze    COMPLEX (ADAPTOR PROTEIN/PEPTIDE) 1b07    SH3 DOMAIN 1bfi    SH2 DOMAIN 1bfj    SH2 DOMAIN 1bhf    COMPLEX (SH2 DOMAIN/INHIBITOR) 1bhh    SH2 DOMAIN 1bkl    V-SRC SH2 DOMAIN 1bkm    TRANSFORMING PROTEIN 1blj    PHOSPHORYLATION 1blk    PHOSPHORYLATION 1bm2    HORMONE/GROWTH FACTOR 1bmb    HORMONE/GROWTH FACTOR 1bu1    TRANSFERASE 1byg    TRANSFERASE 1cj1    SIGNALING PROTEIN 1cka    COMPLEX (ONCOGENE PROTEIN/PEPTIDE) 1ckb    COMPLEX (ONCOGENE PROTEIN/PEPTIDE) 1csk    PHOSPHOTRANSFERASE 1csy    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1csz    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1cwd    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1cwe    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1d1z    GENE REGULATION 1d4t    SIGNALING PROTEIN 1d4w    SIGNALING PROTEIN 1f1w    TRANSFERASE 1f2f    TRANSFERASE 1fbz    TRANSFERASE 1fgi    PROTEIN KINASE 1fgk    PHOSPHOTRANSFERASE 1fmk    PHOSPHOTRANSFERASE 1fpu    TRANSFERASE 1fvr    TRANSFERASE 1fyr    HORMONE/GROWTH FACTOR 1g83    TRANSFERASE 1gag    TRANSFERASE, SIGNALING PROTEIN 1gbq    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1gbr    SIGNAL TRANSDUCTION PROTEIN 1ghu    SRC HOMOLOGY 2 DOMAIN 1gjo    TRANSFERASE 1gl5    TRANSFERASE 1h9o    COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR) 1hcs    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1hct    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1i3z    SIGNALING PROTEIN 1i44    TRANSFERASE 1iep    TRANSFERASE 1ijr    TRANSFERASE/SIGNALING PROTEIN 1ir3    COMPLEX (TRANSFERASE/SUBSTRATE) 1irk    TRANSFERASE (PHOSPHOTRANSFERASE) 1is0    TRANSFERASE 1jeg    TRANSFERASE/HYDROLASE 1jpa    TRANSFERASE 1jqh    TRANSFERASE 1ju5    PROTEIN BINDING/TRANSFERASE 1jwo    TRANSFERASE 1jyq    SIGNALING PROTEIN 1jyr    SIGNALING PROTEIN 1jyu    SIGNALING PROTEIN 1k2p    TRANSFERASE 1k3a    TRANSFERASE 1k9a    TRANSFERASE 1ka6    IMMUNE SYSTEM 1ka7    IMMUNE SYSTEM 1kc2    TRANSFERASE 1ksw    TRANSFERASE 1lcj    COMPLEX (KINASE/PEPTIDE) 1lck    COMPLEX (KINASE/PEPTIDE) 1lkk    COMPLEX (TYROSINE KINASE/PEPTIDE) 1lkl    COMPLEX (TYROSINE KINASE/PEPTIDE) 1luf    TRANSFERASE 1lui    TRANSFERASE 1luk    TRANSFERASE 1lum    TRANSFERASE 1lun    TRANSFERASE 1m14    TRANSFERASE 1m17    TRANSFERASE 1m27    SIGNALING PROTEIN, TRANSFERASE 1m30    PROTEIN BINDING 1m3a    PROTEIN BINDING 1m3b    PROTEIN BINDING 1m3c    PROTEIN BINDING 1m52    TRANSFERASE 1m61    TRANSFERASE 1m7n    TRANSFERASE 1mil    TRANSFORMING PROTEIN 1mp8    TRANSFERASE 1mqb    TRANSFERASE 1mw4    HORMONE/GROWTH FACTOR/TRANSFERASE 1nzl    TRANSFERASE 1nzv    TRANSFERASE 1o41    SIGNALING PROTEIN 1o42    SIGNALING PROTEIN 1o43    SIGNALING PROTEIN 1o44    SIGNALING PROTEIN 1o45    SIGNALING PROTEIN 1o46    SIGNALING PROTEIN 1o47    SIGNALING PROTEIN 1o48    SIGNALING PROTEIN 1o49    SIGNALING PROTEIN 1o4a    SIGNALING PROTEIN 1o4b    SIGNALING PROTEIN 1o4c    SIGNALING PROTEIN 1o4d    SIGNALING PROTEIN 1o4e    SIGNALING PROTEIN 1o4f    SIGNALING PROTEIN 1o4g    SIGNALING PROTEIN 1o4h    SIGNALING PROTEIN 1o4i    SIGNALING PROTEIN 1o4j    SIGNALING PROTEIN 1o4k    SIGNALING PROTEIN 1o4l    SIGNALING PROTEIN 1o4m    SIGNALING PROTEIN 1o4n    SIGNALING PROTEIN 1o4o    SIGNALING PROTEIN 1o4p    SIGNALING PROTEIN 1o4q    SIGNALING PROTEIN 1o4r    SIGNALING PROTEIN 1oec    TRANSFERASE 1oot    STRUCTURAL GENOMICS 1opj    TRANSFERASE 1opk    TRANSFERASE 1opl    TRANSFERASE 1p13    TRANSFERASE 1p14    TRANSFERASE 1p4o    HORMONE/GROWTH FACTOR 1pic    COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR) 1pkg    TRANSFERASE ACTIVATOR 1qad    TRANSFERASE 1qcf    TYROSINE KINASE 1qg1    HORMONE/GROWTH FACTOR 1qly    TYROSINE-PROTEIN KINASE 1qpc    TRANSFERASE 1qpd    TRANSFERASE 1qpe    TRANSFERASE 1qpj    TRANSFERASE 1r0p    TRANSFERASE 1r1w    TRANSFERASE 1rja    TRANSFERASE 1rjb    TRANSFERASE 1rpy    SIGNALING PROTEIN 1s1n    CELL ADHESION 1sha    PHOSPHOTRANSFERASE 1shb    PHOSPHOTRANSFERASE 1shd    COMPLEX(TRANSFERASE/PEPTIDE) 1skj    TYROSINE-PROTEIN KINASE 1sm2    TRANSFERASE 1snu    TRANSFERASE 1snx    TRANSFERASE 1spr    TRANSFERASE(PHOSPHOTRANSFERASE) 1sps    TRANSFERASE(PHOSPHOTRANSFERASE) 1ssh    CONTRACTILE PROTEIN 1t45    TRANSFERASE ACTIVATOR 1t46    TRANSFERASE ACTIVATOR 1tce    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1tze    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1u46    TRANSFERASE 1u4d    TRANSFERASE 1u54    TRANSFERASE 1u59    TRANSFERASE 1u5s    METAL BINDING PROTEIN 1ujy    SIGNALING PROTEIN 1uwj    KINASE 1vjy    TRANSFERASE 1vr2    TRANSFERASE 1w1f    SH3-DOMAIN 1wa7    SH3 DOMAIN 1wx6    STRUCTURAL GENOMICS, UNKNOWN FUNCTION 1x0n    PEPTIDE BINDING PROTEIN 1x27    SIGNALING PROTEIN 1x2k    SIGNALING PROTEIN 1x2p    TRANSFERASE 1x6c    SIGNALING PROTEIN 1x6g    SIGNALING PROTEIN 1xba    TRANSFERASE 1xbb    TRANSFERASE 1xbc    TRANSFERASE 1xkk    TRANSFERASE 1y57    TRANSFERASE 1y6a    TRANSFERASE 1y6b    TRANSFERASE 1yi6    TRANSFERASE 1yoj    TRANSFERASE 1yol    TRANSFERASE 1yom    TRANSFERASE 1yvj    TRANSFERASE 1ywn    TRANSFERASE 1z3k    STRUCTURAL GENOMICS, UNKNOWN FUNCTION 1zfp    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 2a08    PROTEIN BINDING 2a36    SIGNALING PROTEIN 2a37    SIGNALING PROTEIN 2abl    TRANSFERASE 2aoa    TRANSFERASE 2aob    TRANSFERASE 2aug    SIGNALING PROTEIN 2auh    TRANSFERASE/SIGNALING PROTEIN 2azs    SIGNALING PROTEIN 2azv    SIGNALING PROTEIN 2b3o    HYDROLASE 2b7a    TRANSFERASE 2bdf    TRANSFERASE 2bdj    TRANSFERASE 2c0i    TRANSFERASE 2c0o    TRANSFERASE 2c0t    TRANSFERASE 2ci8    SH2-DOMAIN 2ci9    SH2-DOMAIN/COMPLEX 2cia    SH2-DOMAIN 2cs0    SIGNALING PROTEIN 2d8h    UNKNOWN FUNCTION 2df6    SIGNALING PROTEIN 2dl3    CELL ADHESION, SIGNALING PROTEIN 2dl4    SIGNALING PROTEIN 2dlm    CELL ADHESION 2dly    TRANSFERASE 2dm0    TRANSFERASE 2dq7    TRANSFERASE 2dx0    HYDROLASE 2e2b    TRANSFERASE 2eb2    TRANSFERASE 2eb3    TRANSFERASE 2ecd    SIGNALING PROTEIN 2ecz    SIGNALING PROTEIN 2ekx    SIGNALING PROTEIN 2eo3    SIGNALING PROTEIN 2esw    SIGNALING PROTEIN 2etm    TRANSFERASE 2etz    TRANSFERASE 2eu0    TRANSFERASE 2eva    TRANSFERASE/TRANSFERASE ACTIVATOR 2eyv    SIGNALING PROTEIN 2eyw    SIGNALING PROTEIN 2f4j    TRANSFERASE 2fb8    TRANSFERASE 2fgi    TRANSFERASE 2fo0    TRANSFERASE 2fry    PROTEIN BINDING 2g15    TRANSFERASE 2g1t    TRANSFERASE 2g2f    TRANSFERASE 2g2h    TRANSFERASE 2g2i    TRANSFERASE 2g6f    SIGNALING PROTEIN 2gbq    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 2gqg    TRANSFERASE 2gs2    TRANSFERASE 2gs6    TRANSFERASE 2gs7    TRANSFERASE 2gsf    TRANSFERASE 2h46    HORMONE/GROWTH FACTOR 2h5k    HORMONE/GROWTH FACTOR 2h8h    TRANSFERASE 2hck    TRANSFERASE 2hdv    SIGNALING PROTEIN 2hdx    SIGNALING PROTEIN 2hel    SIGNALING PROTEIN, TRANSFERASE 2hen    TRANSFERASE 2hiw    TRANSFERASE 2hk5    TRANSFERASE 2huw    HORMONE/GROWTH FACTOR 2hwo    TRANSFERASE 2hwp    TRANSFERASE 2hyy    TRANSFERASE 2hz0    TRANSFERASE 2hz4    TRANSFERASE 2hzi    TRANSFERASE 2hzn    TRANSFERASE 2i0v    TRANSFERASE 2i0y    TRANSFERASE 2i1m    TRANSFERASE 2ijm    SIGNALING PROTEIN,TRANSFERASE 2itn    TRANSFERASE 2ito    TRANSFERASE 2itp    TRANSFERASE 2itq    TRANSFERASE 2itt    TRANSFERASE 2itu    TRANSFERASE 2itv    TRANSFERASE 2itw    TRANSFERASE 2itx    TRANSFERASE 2ity    TRANSFERASE 2itz    TRANSFERASE 2ivs    TRANSFERASE 2ivt    TRANSFERASE 2ivu    TRANSFERASE 2ivv    TRANSFERASE 2j0j    TRANSFERASE 2j0k    TRANSFERASE 2j0l    TRANSFERASE 2j0m    TRANSFERASE 2j5e    TRANSFERASE 2j5f    TRANSFERASE 2j6m    TRANSFERASE 2jit    TRANSFERASE 2jiu    TRANSFERASE 2jiv    TRANSFERASE 2jkk    TRANSFERASE 2jkm    TRANSFERASE 2jko    TRANSFERASE 2jkq    TRANSFERASE 2jyq    TRANSFERASE 2o2w    SIGNALING PROTEIN 2o31    SIGNALING PROTEIN 2o9s    SIGNALING PROTEIN 2o9v    SIGNALING PROTEIN/CELL ADHESION 2of2    TRANSFERASE 2of4    TRANSFERASE 2ofu    TRANSFERASE 2ofv    TRANSFERASE 2og8    TRANSFERASE 2ogv    TRANSFERASE 2oh4    TRANSFERASE 2oiq    TRANSFERASE 2oj9    TRANSFERASE 2oo8    TRANSFERASE 2oq1    TRANSFERASE 2osc    TRANSFERASE 2ozo    TRANSFERASE 2p0c    TRANSFERASE 2p2h    TRANSFERASE 2p2i    TRANSFERASE 2p4i    TRANSFERASE 2p4r    LIGASE 2pl0    TRANSFERASE 2psq    TRANSFERASE 2ptk    TYROSINE-PROTEIN KINASE 2pvf    TRANSFERASE 2pvy    TRANSFERASE 2pwl    TRANSFERASE 2py3    TRANSFERASE 2pz5    TRANSFERASE 2pzp    TRANSFERASE 2pzr    TRANSFERASE 2q0b    TRANSFERASE 2qi8    SIGNALING PROTEIN, TRANSFERASE 2qlq    TRANSFERASE 2qms    SIGNALING PROTEIN 2qo2    TRANSFERASE 2qo7    TRANSFERASE 2qo9    TRANSFERASE 2qob    TRANSFERASE 2qoc    TRANSFERASE 2qod    TRANSFERASE 2qof    TRANSFERASE 2qoh    TRANSFERASE 2qoi    TRANSFERASE 2qok    TRANSFERASE 2qol    TRANSFERASE 2qon    TRANSFERASE 2qoo    TRANSFERASE 2qoq    TRANSFERASE 2qq7    TRANSFERASE 2qu5    TRANSFERASE 2qu6    TRANSFERASE 2r2p    TRANSFERASE 2r4b    TRANSFERASE 2rei    TRANSFERASE 2rf9    TRANSFERASE 2rfd    TRANSFERASE 2rfe    TRANSFERASE 2rfn    TRANSFERASE 2rfs    TRANSFERASE 2rgp    TRANSFERASE 2rl5    TRANSFERASE 2rmx    SIGNALING PROTEIN 2src    TYROSINE-PROTEIN KINASE 2v7a    TRANSFERASE 2vif    SIGNALING PROTEIN 2vwu    TRANSFERASE 2vwv    TRANSFERASE 2vww    TRANSFERASE 2vwx    TRANSFERASE 2vwy    TRANSFERASE 2vwz    TRANSFERASE 2vx0    TRANSFERASE 2vx1    TRANSFERASE 2w1i    TRANSFERASE 2ysx    SIGNALING PROTEIN 2yt6    CELL CYCLE 2yu7    SIGNALING PROTEIN 2yup    CELL ADHESION 2z60    TRANSFERASE 2z8c    TRANSFERASE 2zm1    TRANSFERASE 2zm3    TRANSFERASE 2zm4    TRANSFERASE 2zv7    TRANSFERASE 2zv8    TRANSFERASE 2zv9    TRANSFERASE 2zva    TRANSFERASE 2zyb    TRANSFERASE 3b2t    TRANSFERASE 3b2w    TRANSFERASE 3b8q    TRANSFERASE 3b8r    TRANSFERASE 3bbt    TRANSFERASE 3bbw    TRANSFERASE 3bce    TRANSFERASE 3be2    TRANSFERASE 3bea    TRANSFERASE 3bel    TRANSFERASE 3bkb    TRANSFERASE 3bpr    TRANSFERASE 3brb    TRANSFERASE 3bu3    TRANSFERASE 3bu5    TRANSFERASE 3bu6    TRANSFERASE 3bym    TRANSFERASE 3byo    TRANSFERASE 3bys    TRANSFERASE 3byu    TRANSFERASE 3bz3    TRANSFERASE 3c1x    TRANSFERASE 3c4f    TRANSFERASE 3c7q    TRANSFERASE 3cbl    TRANSFERASE 3cc6    TRANSFERASE 3ccn    TRANSFERASE 3cd3    TRANSFERASE 3cd8    TRANSFERASE 3ce3    TRANSFERASE 3cjf    TRANSFERASE 3cjg    TRANSFERASE 3cly    TRANSFERASE 3cp9    TRANSFERASE 3cpb    TRANSFERASE 3cpc    TRANSFERASE 3cs9    TRANSFERASE 3cth    TRANSFERASE 3ctj    TRANSFERASE 3d7t    TRANSFERASE 3d7u    TRANSFERASE 3d94    TRANSFERASE 3dk3    TRANSFERASE 3dk6    TRANSFERASE 3dk7    TRANSFERASE 3dko    TRANSFERASE 3dqw    TRANSFERASE 3dqx    TRANSFERASE 3dtw    TRANSFERASE 3dzq    TRANSFERASE 3e62    TRANSFERASE 3e63    TRANSFERASE 3e64    TRANSFERASE 3efj    TRANSFERASE 3efk    TRANSFERASE 3ekk    TRANSFERASE 3ekn    TRANSFERASE 3el7    TRANSFERASE 3el8    TRANSFERASE 3emg    TRANSFERASE 3en4    TRANSFERASE 3en5    TRANSFERASE 3en6    TRANSFERASE 3en7    TRANSFERASE 3eqp    TRANSFERASE 3eqr    TRANSFERASE 3eyg    TRANSFERASE 3eyh    TRANSFERASE 3f5p    TRANSFERASE 3f66    TRANSFERASE 3f6x    TRANSFERASE 3faa    TRANSFERASE 3fup    TRANSFERASE 3fxx    TRANSFERASE 3fy2    TRANSFERASE 3gbq    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 3hck    TRANSFERASE 3lck    TYROSINE-PROTEIN KINASE 4gbq    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) PSSH: ID    Description Q53EL3    UNKNOWN P41240    UNKNOWN
Diseases	OMIM: OMIM ID    Name    Alt Name 124095    CYTOPLASMIC TYROSINE KINASE; CSK    c-SRC TYROSINE KINASE
Gene Ontology	GO: GO ID    Description GO:0000166    nucleotide binding GO:0004672    protein kinase activity GO:0004674    protein serine/threonine kinase activity GO:0004713    protein tyrosine kinase activity GO:0004715    non-membrane spanning protein tyrosine kinase activity GO:0005515    protein binding GO:0005524    ATP binding GO:0005737    cytoplasm GO:0005886    plasma membrane GO:0005911    cell-cell junction GO:0006468    protein amino acid phosphorylation GO:0008022    protein C-terminus binding GO:0008285    negative regulation of cell proliferation GO:0016740    transferase activity
Pathway	KEGG: KEGG PATHWAY ID    Name hsa04062    Chemokine signaling pathway hsa05120    Epithelial cell signaling in Helicobacter pylori infection hsa04722    Neurotrophin signaling pathway hsa04810    Regulation of actin cytoskeleton Panther: ID    Description P00053    T cell activation P00049    Parkinson disease P00034    Integrin signalling pathway
Chemicals	DrugBank: ID    Name    Synonyms DB02010    Staurosporine    HMDB: ID    Name    Synonyms
Orthology	Orthology Relations: Gene Gene Description Organism Orthology type Orthologs Orthologs Description ENSG00000103653 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240] Pan_troglodytes one2one ENSPTRG00000007282 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]CSK Pongo_pygmaeus one2one ENSPPYG00000006646 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Macaca_mulatta one2one ENSMMUG00000015267 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Tarsius_syrichta one2one ENSTSYG00000003060 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Equus_caballus one2one ENSECAG00000013581 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]LOC100051462 Tupaia_belangeri one2one ENSTBEG00000006632 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Felis_catus one2one ENSFCAG00000000347 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Tursiops_truncatus one2one ENSTTRG00000007997 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Loxodonta_africana one2one ENSLAFG00000007435 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Myotis_lucifugus one2one ENSMLUG00000013625 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Otolemur_garnettii one2one ENSOGAG00000005591 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Pteropus_vampyrus one2one ENSPVAG00000012946 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Bos_taurus one2one ENSBTAG00000021424 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase). [Source:UniProtKB/Swiss-Prot;Acc:Q0VBZ0][hgnc]CSK Procavia_capensis one2one ENSPCAG00000002321 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Canis_familiaris one2one ENSCAFG00000017945 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Dasypus_novemcinctus one2one ENSDNOG00000002772 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Cavia_porcellus one2one ENSCPOG00000003446 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Mus_musculus one2one ENSMUSG00000032312 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase MPK-2) (p50CSK) [Source:UniProtKB/Swiss-Prot;Acc:P41241][hgnc]Csk Ochotona_princeps one2one ENSOPRG00000010512 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Rattus_norvegicus one2one ENSRNOG00000019374 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase). [Source:UniProtKB/Swiss-Prot;Acc:P32577][hgnc]Csk Dipodomys_ordii one2one ENSDORG00000013011 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase MPK-2) (p50CSK) [Source:UniProtKB/Swiss-Prot;Acc:P41241][hgnc] Sorex_araneus one2one ENSSARG00000009659 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Monodelphis_domestica one2one ENSMODG00000009310 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Gallus_gallus one2one ENSGALG00000001318 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc]CSK Tetraodon_nigroviridis one2many ENSTNIG00000011931 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Gasterosteus_aculeatus one2many ENSGACG00000014659 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Oryzias_latipes one2many ENSORLG00000014381 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Xenopus_tropicalis one2one ENSXETG00000021139 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Danio_rerio one2many ENSDARG00000067996 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Danio_rerio one2many ENSDARG00000070805 c-src tyrosine kinase [Source:RefSeq_peptide;Acc:NP_001071067][hgnc]LOC100000779 Danio_rerio one2many ENSDARG00000051930 [hgnc]LOC563480 Gasterosteus_aculeatus one2many ENSGACG00000009794 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Takifugu_rubripes one2one ENSTRUG00000017074 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Tetraodon_nigroviridis one2many ENSTNIG00000016046 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Oryzias_latipes one2many ENSORLG00000004867 Tyrosine-protein kinase CSK (EC 2.7.10.2) (C-SRC kinase) (Protein-tyrosine kinase CYL) [Source:UniProtKB/Swiss-Prot;Acc:P41240][hgnc] Ciona_savignyi one2many ENSCSAVG00000003351 [hgnc] Ciona_intestinalis many2many ENSCING00000003438 [hgnc] Ciona_intestinalis many2many ENSCING00000017722 [hgnc]