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Summary sheet information for Effector 'Tubulin-Homo sapiens-21'
Name Tubulin-Homo sapiens-21
Description RecName: Full=Tubulin gamma-1 chain;AltName: Full=Gamma-1-tubulin;AltName: Full=Gamma-tubulin complex component 1; Short=GCP-1
Class
Family Tubulins
Sub_family Tubulins
type Tubulin
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 17
Gene Start: 38015220
Gene End: 38020773
Ensembl Contig View
Ensembl Genes:
ENSG00000131462
EMBL:
EMBL ID  Description
AK313339  Homo sapiens cDNA, FLJ93861, highly similar to Homo sapiens tubulin, gamma 1 (TUBG1), mRNA.
BC000619  Homo sapiens tubulin, gamma 1, mRNA (cDNA clone MGC:1593 IMAGE:3345973), complete cds.
BT019931  Homo sapiens tubulin, gamma 1 mRNA, complete cds.
CR407642  Homo sapiens full open reading frame cDNA clone RZPDo834F112D for gene TUBG1, tubulin, gamma 1 complete cds, without stopcodon.
M61764  Human gamma-tubulin mRNA, complete cds.

EntrezGene:
ID  Description
LOC100133673  similar to Tubulin, gamma 1
TUBG1  tubulin, gamma 1
RefSeq DNA:
ID  Description
NM_001070  Homo sapiens tubulin, gamma 1 (TUBG1), mRNA.
XM_001725120  PREDICTED: Homo sapiens similar to Tubulin, gamma 1 (LOC100133673), mRNA.

UniGene:
ID  Description
Hs.279669  Tubulin, gamma 1, mRNA (cDNA clone MGC:1593 IMAGE:3345973)

Proteins
Ensembl Proteins:
ENSP00000251413
Entrez Proteins:
AAA52620.1; AAH00619.1; AAV38734.1; BAG36143.1; CAG28570.1
RefSeq Proteins:
ID  Description
NP_001061  tubulin, gamma 1 [Homo sapiens].
XP_001725172  PREDICTED: similar to Tubulin, gamma 1 [Homo sapiens].

UniProt:
ID  Description
Q53X79  SubName: Full=TUBG1 protein; SubName: Full=cDNA, FLJ93861, highly similar to Homo sapiens tubulin, gamma 1 (TUBG1), mRNA; Flags: Fragment;
P23258  RecName: Full=Tubulin gamma-1 chain; AltName: Full=Gamma-1-tubulin; AltName: Full=Gamma-tubulin complex component 1; Short=GCP-1;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     Tubulin-Homo sapiens-21    

InterPro:
ID  Name
IPR017975  Tubulin_CS
IPR003008  Tubulin_FtsZ
IPR000217  Tubulin
IPR008280  Tub_FtsZ_C
IPR002454  Gamma_tubulin
Pfam:
ID  Description
Tubulin  Tubulin/FtsZ family, GTPase domain
Tubulin_C  Tubulin/FtsZ family, C-terminal domain

Structure
PDB:
ID
1Z5V
1Z5W
3CB2
HSSP:
ID  Description
1z5v  STRUCTURAL PROTEIN
1z5w  STRUCTURAL PROTEIN
3cb2  STRUCTURAL PROTEIN, HYDROLASE
PSSH:
ID  Description
Q53X79  UNKNOWN
P23258  UNKNOWN
Diseases
OMIM:
OMIM ID  Name  Alt Name
191135  TUBULIN, GAMMA-1; TUBG1   TUBG TUBULIN-GAMMA COMPLEX-ASSOCIATED PROTEIN 1; TUBGCP1
Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0000212  meiotic spindle organization
GO:0000226  microtubule cytoskeleton organization
GO:0000242  pericentriolar material
GO:0000794  condensed nuclear chromosome
GO:0000930  gamma-tubulin complex
GO:0003924  GTPase activity
GO:0005198  structural molecule activity
GO:0005200  structural constituent of cytoskeleton
GO:0005515  protein binding
GO:0005525  GTP binding
GO:0005737  cytoplasm
GO:0005813  centrosome
GO:0005816  spindle pole body
GO:0005827  polar microtubule
GO:0005874  microtubule
GO:0005876  spindle microtubule
GO:0005881  cytoplasmic microtubule
GO:0007017  microtubule-based process
GO:0007018  microtubule-based movement
GO:0043234  protein complex
GO:0051258  protein polymerization
Pathway
KEGG:
KEGG PATHWAY ID  Name
Panther:
ID  Description
Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000131462 Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258] Pan_troglodytesone2one ENSPTRG00000009211PREDICTED: Pan troglodytes hypothetical LOC472356 (LOC472356), mRNA. [Source:RefSeq_dna;Acc:XR_022733][hgnc]LOC472356
Pongo_pygmaeusone2one ENSPPYG00000008384Putative uncharacterized protein DKFZp468N0827. [Source:UniProtKB/TrEMBL;Acc:Q5RB24][hgnc]
Macaca_mulattaone2one ENSMMUG00000016797Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258][hgnc]
Microcebus_murinusone2one ENSMICG00000010279Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258][hgnc]
Tupaia_belangerione2one ENSTBEG00000015835Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258][hgnc]
Oryctolagus_cuniculusone2one ENSOCUG00000015260Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258][hgnc]
Otolemur_garnettiione2one ENSOGAG00000009878Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258][hgnc]
Dipodomys_ordiione2many ENSDORG00000006534[hgnc]
Rattus_norvegicusone2one ENSRNOG00000020213Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1). [Source:UniProtKB/Swiss-Prot;Acc:P83888][hgnc]Tubg1
Mus_musculusone2one ENSMUSG00000035198Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P83887][hgnc]Tubg1
Ochotona_princepsone2one ENSOPRG00000012349Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258][hgnc]
Cavia_porcellusone2one ENSCPOG00000008842Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258][hgnc]
Dipodomys_ordiione2many ENSDORG00000016400[hgnc]
Gallus_gallusone2many ENSGALG00000003150[hgnc]TUBG1
Danio_rerioone2many ENSDARG00000015610tubulin, gamma-like [Source:RefSeq_peptide;Acc:NP_957202][hgnc]tubgl
Oryzias_latipesone2many ENSORLG00000004426Tubulin gamma-2 chain (Gamma-2-tubulin) [Source:UniProtKB/Swiss-Prot;Acc:Q9NRH3][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000008462Tubulin gamma-2 chain (Gamma-2-tubulin) [Source:UniProtKB/Swiss-Prot;Acc:Q9NRH3][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000004489Tubulin gamma-1 chain (Gamma-1-tubulin) (Gamma-tubulin complex component 1) (GCP-1) [Source:UniProtKB/Swiss-Prot;Acc:P23258][hgnc]
Takifugu_rubripesone2many ENSTRUG00000014769Tubulin gamma-2 chain (Gamma-2-tubulin) [Source:UniProtKB/Swiss-Prot;Acc:Q9NRH3][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000011691Tubulin gamma-2 chain (Gamma-2-tubulin) [Source:UniProtKB/Swiss-Prot;Acc:Q9NRH3][hgnc]
Ciona_savignyione2many ENSCSAVG00000008917[hgnc]
Drosophila_melanogastermany2many FBgn0004176[hgnc]gammaTub23C
Anopheles_gambiaeone2many AGAP007834[hgnc]AgaP_ENSANGG00000016077
Aedes_aegyptimany2many AAEL013064tubulin gamma chain[hgnc]
Aedes_aegyptimany2many AAEL012843tubulin gamma chain[hgnc]
Drosophila_melanogastermany2many FBgn0010097[hgnc]gammaTub37C