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Summary sheet information for Effector 'Tubulin-Homo sapiens-13'
Name Tubulin-Homo sapiens-13
Description RecName: Full=Tubulin beta-2B chain
Class
Family Tubulins
Sub_family Tubulins
type Tubulin
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 6
Gene Start: 3169516
Gene End: 3172870
Ensembl Contig View
Ensembl Genes:
ENSG00000137285
EMBL:
EMBL ID  Description
AF035316  Homo sapiens clone 23678 mRNA, partial cds.
AK289433  Homo sapiens cDNA FLJ78522 complete cds, highly similar to Homo sapiens tubulin, beta 2 (TUBB2), mRNA.
AL050056  Homo sapiens mRNA; cDNA DKFZp566F223 (from clone DKFZp566F223); partial cds
AL445309  Human DNA sequence from clone RP11-506K6 on chromosome 6 Contains the gene for a novel protein similar to tubulin beta polypeptide TUBB, a novel gene, the 3' end of the gene for the possible ortholog of rat ion transporter protein (NRITP) and five CpG islands.
BC001352  Homo sapiens tubulin, beta 2B, mRNA (cDNA clone MGC:8685 IMAGE:2964590), complete cds.
BC063610  Homo sapiens tubulin, beta 2B, mRNA (cDNA clone MGC:70829 IMAGE:4941267), complete cds.
BC127872  Homo sapiens tubulin, beta 2B, mRNA (cDNA clone IMAGE:40131580), partial cds.
BC127874  Homo sapiens cDNA clone IMAGE:40134249, partial cds.
BT019930  Homo sapiens tubulin, beta polypeptide paralog mRNA, complete cds.
CH471087  Homo sapiens 211000035831101 genomic scaffold, whole genome shotgun sequence.
CR456788  Homo sapiens full open reading frame cDNA clone RZPDo834G104D for gene MGC8685, tubulin, beta polypeptide paralog; complete cds, incl. stopcodon.

EntrezGene:
ID  Description
TUBB2B  tubulin, beta 2B
RefSeq DNA:
ID  Description
NM_178012  Homo sapiens tubulin, beta 2B (TUBB2B), mRNA.

UniGene:
ID  Description
Hs.300701  Clone 23678
Hs.605385  Transcribed locus

Proteins
Ensembl Proteins:
ENSP00000259818
Entrez Proteins:
AAB88188.1; AAH01352.1; AAH63610.1; AAI27873.2; AAI27875.1; AAV38733.1; BAF82122.1; CAB43252.1; CAG33069.1; CAI40952.1; EAW55125.1
RefSeq Proteins:
ID  Description
NP_821080  tubulin, beta 2B [Homo sapiens].

UniProt:
ID  Description
A1L195  SubName: Full=TUBB2B protein; Flags: Fragment;
A1L196  SubName: Full=Putative uncharacterized protein; Flags: Fragment;
A8K068  SubName: Full=cDNA FLJ78522, highly similar to Homo sapiens tubulin, beta 2 (TUBB2), mRNA; SubName: Full=Tubulin, beta 2B, isoform CRA_a;
O43209  SubName: Full=Homo sapiens clone 23678; Flags: Fragment;
Q9UGA2  SubName: Full=Putative uncharacterized protein DKFZp566F223; Flags: Fragment;
Q9BVA1  RecName: Full=Tubulin beta-2B chain;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     Tubulin-Homo sapiens-13    

InterPro:
ID  Name
IPR017975  Tubulin_CS
IPR000158  Cell_division_FtsZ_N
IPR008280  Tub_FtsZ_C
IPR013838  Beta-tubulin_BS
IPR002453  Beta_tubulin
IPR003008  Tubulin_FtsZ
IPR000217  Tubulin
IPR010916  TonB_box_CS
Pfam:
ID  Description
Tubulin  Tubulin/FtsZ family, GTPase domain
Tubulin_C  Tubulin/FtsZ family, C-terminal domain

Structure
PDB:
ID
HSSP:
ID  Description
1ia0  TRANSPORT PROTEIN
1sa0  CELL CYCLE
1tub  MICROTUBULES
1z2b  CELL CYCLE
1z5v  STRUCTURAL PROTEIN
1z5w  STRUCTURAL PROTEIN
2btq  CYTOSKELETAL PROTEIN/COMPLEX
3cb2  STRUCTURAL PROTEIN, HYDROLASE
3du7  CELL CYCLE
3e22  CELL CYCLE
PSSH:
ID  Description
Q9UGA2  UNKNOWN
A1L195  UNKNOWN
A1L196  UNKNOWN
O43209  UNKNOWN
Diseases
OMIM:
OMIM ID  Name  Alt Name
Gene Ontology
GO:
GO ID  Description
GO:0000166  nucleotide binding
GO:0003924  GTPase activity
GO:0005198  structural molecule activity
GO:0005525  GTP binding
GO:0005737  cytoplasm
GO:0005874  microtubule
GO:0007017  microtubule-based process
GO:0007018  microtubule-based movement
GO:0007067  mitosis
GO:0030182  neuron differentiation
GO:0043234  protein complex
GO:0051258  protein polymerization
Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04540  Gap junction
hsa05130  Pathogenic Escherichia coli infection

Panther:
ID  Description
P00016  Cytoskeletal regulation by Rho GTPase
P00029  Huntington disease
Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000137285 Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1] Drosophila_melanogastermany2many FBgn0003887[hgnc]betaTub56D
Macaca_mulattaone2one ENSMMUG00000023785Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Pan_troglodytesone2one ENSPTRG00000027750Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]TUBB2B
Pongo_pygmaeusone2one ENSPPYG00000016180Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Felis_catusone2one ENSFCAG00000014628Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Equus_caballusone2one ENSECAG00000000341Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]LOC100059595
Pteropus_vampyrusone2one ENSPVAG00000013676Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Otolemur_garnettiiapprent_one2one ENSOGAG00000007496Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Tursiops_truncatusone2one ENSTTRG00000006144Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Oryctolagus_cuniculusone2one ENSOCUG00000013014Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Myotis_lucifugusapprent_one2one ENSMLUG00000016179Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Bos_taurusapprent_one2one ENSBTAG00000004093Tubulin beta-2B chain. [Source:UniProtKB/Swiss-Prot;Acc:Q6B856][hgnc]TUBB2B
Ochotona_princepsone2one ENSOPRG00000000403Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Spermophilus_tridecemlineatusapprent_one2one ENSSTOG00000001568Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Loxodonta_africanaapprent_one2one ENSLAFG00000016746Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Cavia_porcellusone2one ENSCPOG00000012880Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000001779Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Dipodomys_ordiione2one ENSDORG00000014282Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9CWF2][hgnc]
Tupaia_belangerione2many ENSTBEG00000004854[hgnc]
Rattus_norvegicusone2one ENSRNOG00000017445Tubulin beta-2B chain (T beta-15). [Source:UniProtKB/Swiss-Prot;Acc:Q3KRE8][hgnc]Tubb2b
Mus_musculusone2one ENSMUSG00000045136Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9CWF2][hgnc]Tubb2b
Echinops_telfairiapprent_one2one ENSETEG00000006085Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Canis_familiarisapprent_one2one ENSCAFG00000009337Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]LOC611286
Gallus_gallusmany2many ENSGALG00000012821Tubulin beta-2 chain (Beta-tubulin class-II). [Source:UniProtKB/Swiss-Prot;Acc:P32882][hgnc]LOC768337
Gallus_gallusmany2many ENSGALG00000013855Gallus gallus tubulin, beta 2B (TUBB2B), mRNA. [Source:RefSeq_dna;Acc:NM_001004400][hgnc]TUBB2B
Monodelphis_domesticaapprent_one2one ENSMODG00000008762Tubulin beta-2B chain [Source:UniProtKB/Swiss-Prot;Acc:Q9BVA1][hgnc]
Xenopus_tropicalisone2many ENSXETG00000018032Tubulin, beta 2. [Source:UniProtKB/TrEMBL;Acc:Q6P367][hgnc]
Drosophila_melanogastermany2many FBgn0003889[hgnc]betaTub85D
Ciona_intestinalisone2many ENSCING00000007589[hgnc]
Ciona_savignyione2many ENSCSAVG00000004683[hgnc]
Anopheles_gambiaeone2many AGAP010929[hgnc]AgaP_ENSANGG00000010545
Aedes_aegyptione2many AAEL002851tubulin beta chain[hgnc]
Saccharomyces_cerevisiaeone2many YFL037WTubulin beta chain (Beta-tubulin). [Source:UniProtKB/Swiss-Prot;Acc:P02557][hgnc]TUB2