Human-gpDB    A database of human GPCRs, G-proteins, Effectors and their interactions

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	Summary sheet information for Effector 'Src tyrosine kinase-Homo sapiens-2'
Name	Src tyrosine kinase-Homo sapiens-2
Description	RecName: Full=Proto-oncogene tyrosine-protein kinase Src; EC=2.7.10.2;AltName: Full=pp60c-src; Short=p60-Src; Short=c-Src
Class
Family	Tyr protein kinases
Sub_family	Tyr protein kinases
type	Src tyrosine kinase
Protein features link	Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction	Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes	Gene Location: Chromosome : 20 Gene Start : 35407971 Gene End : 35467867 Ensembl Contig View Ensembl Genes: ENSG00000197122 EMBL: EMBL ID    Description AF077754    Homo sapiens tyrosine kinase pp60c-src (SRC) gene, exon 12 and partial cds. AK024281    Homo sapiens cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to Rattus norvegicus tyrosine protein kinase pp60-c-src mRNA. AL133293    Human DNA sequence from clone RP5-823N20 on chromosome 20 Contains the 5' end of the SRC gene for v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog, the RPL7AL4 gene for ribosomal protein L7A-like 4 (pseudogene) and a CpG island. BC011566    Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), mRNA (cDNA clone MGC:20184 IMAGE:4548399), complete cds. BC051270    Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian), mRNA (cDNA clone MGC:59921 IMAGE:4871614), complete cds. CH471077    Homo sapiens 211000035835434 genomic scaffold, whole genome shotgun sequence. K03212    Human c-src-1 proto-oncogene, exon 6. K03213    Human c-src-1 proto-oncogene, exon 7. K03214    Human c-src-1 proto-oncogene, exon 8. K03215    Human c-src-1 proto-oncogene, exon 9. K03216    Human c-src-1 proto-oncogene, exon 10. K03217    Human c-src-1 proto-oncogene, exon 11. K03218    Human c-src-1 proto-oncogene, exon 12. M16237    Human c-src-1 proto-oncogene, exon 2. M16243    Human c-src-1 proto-oncogene, exon 3. M16244    Human c-src-1 proto-oncogene, exon 4. M16245    Human c-src-1 proto-oncogene, exon 5. X02647    Human c-src gene exon 6 (and joined CDS) X03995    Human c-src gene exon 7 X03996    Human c-src gene exon 8 X03997    Human c-src gene exon 9 X03998    Human c-src gene exon 10 X03999    Human c-src gene exon 11 X04000    Human c-src gene exon 12 EntrezGene: ID    Description SRC    v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) RefSeq DNA: ID    Description NM_005417    Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 1, mRNA. NM_198291    Homo sapiens v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) (SRC), transcript variant 2, mRNA. UniGene: ID    Description Hs.195659    5' non-coding end of the c-Src proto-oncogene Hs.597733    Transcribed locus Hs.675407    Transcribed locus
Proteins	Ensembl Proteins: ENSP00000362659; ENSP00000362668; ENSP00000362680; ENSP00000350941; ENSP00000353950 Entrez Proteins: AAA60584.1; AAC29427.1; AAH11566.1; AAH51270.2; BAB14871.1; CAA26485.1; CAC10573.1; CAC34523.1; EAW76065.1 RefSeq Proteins: ID    Description NP_005408    proto-oncogene tyrosine-protein kinase SRC [Homo sapiens]. NP_938033    proto-oncogene tyrosine-protein kinase SRC [Homo sapiens]. UniProt: ID    Description P12931-2    UNKNOWN Q71UK5    SubName: Full=Tyrosine kinase pp60c-src; Flags: Fragment; Q76P87    SubName: Full=V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Avian) (V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (Avian), isoform CRA_d); Q9H7V3    SubName: Full=cDNA FLJ14219 fis, clone NT2RP3003800, highly similar to Rattus norvegicus tyrosine protein kinase pp60-c-src mRNA; P12931    RecName: Full=Proto-oncogene tyrosine-protein kinase Src; EC=2.7.10.2; AltName: Full=pp60c-src; Short=p60-Src; Short=c-Src;
Domains	SMART: - Hyperlink to SMART; - Hyperlink to ENSEMBL       Src tyrosine kinase-Homo sapiens-2     InterPro: ID    Name IPR000719    Prot_kinase_core IPR017441    Protein_kinase_ATP_bd_CS IPR001452    SH3_domain IPR008266    Tyr_pkinase_AS IPR000980    SH2 IPR001245    Tyr_pkinase Pfam: ID    Description SH2    SH2 domain SH3_1    SH3 domain Pkinase_Tyr    Protein tyrosine kinase
Structure	PDB: ID 1A07 1A08 1A09 1A1A 1A1B 1A1C 1A1E 1FMK 1HCS 1HCT 1KSW 1O41 1O42 1O43 1O44 1O45 1O46 1O47 1O48 1O49 1O4A 1O4B 1O4C 1O4D 1O4E 1O4F 1O4G 1O4H 1O4I 1O4J 1O4K 1O4L 1O4M 1O4N 1O4O 1O4P 1O4Q 1O4R 1SHD 1Y57 1YI6 1YOJ 1YOL 1YOM 2BDF 2BDJ 2H8H 2SRC HSSP: ID    Description 1a07    COMPLEX (TRANSFERASE/PEPTIDE) 1a08    COMPLEX (TRANSFERASE/PEPTIDE) 1a09    COMPLEX (TRANSFERASE/PEPTIDE) 1a0n    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1a1a    COMPLEX (TRANSFERASE/PEPTIDE) 1a1b    COMPLEX (TRANSFERASE/PEPTIDE) 1a1c    COMPLEX (TRANSFERASE/PEPTIDE) 1a1e    COMPLEX (TRANSFERASE/PEPTIDE) 1a81    COMPLEX (TRANSFERASE/PEPTIDE) 1ab2    TRANSFERASE(PHOSPHOTRANSFERASE) 1abo    COMPLEX (KINASE/PEPTIDE) 1abq    KINASE 1ad5    TYROSINE-PROTEIN KINASE 1aey    CYTOSKELETON 1agw    PROTEIN KINASE 1aot    COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN) 1aou    COMPLEX (PROTO-ONCOGENE/EARLY PROTEIN) 1avz    COMPLEX (MYRISTYLATION/TRANSFERASE) 1awo    KINASE 1aww    TRANSFERASE 1awx    TRANSFERASE 1aya    HYDROLASE(SH2 DOMAIN) 1ayb    HYDROLASE(SH2 DOMAIN) 1ayc    HYDROLASE(SH2 DOMAIN) 1ayd    HYDROLASE(SH2 DOMAIN) 1azg    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1b07    SH3 DOMAIN 1bbz    COMPLEX (TRANSFERASE/PEPTIDE) 1bfi    SH2 DOMAIN 1bfj    SH2 DOMAIN 1bhf    COMPLEX (SH2 DOMAIN/INHIBITOR) 1bhh    SH2 DOMAIN 1bk2    SH3-DOMAIN 1bkl    V-SRC SH2 DOMAIN 1bkm    TRANSFORMING PROTEIN 1blj    PHOSPHORYLATION 1blk    PHOSPHORYLATION 1bm2    HORMONE/GROWTH FACTOR 1bmb    HORMONE/GROWTH FACTOR 1bu1    TRANSFERASE 1byg    TRANSFERASE 1cj1    SIGNALING PROTEIN 1cka    COMPLEX (ONCOGENE PROTEIN/PEPTIDE) 1ckb    COMPLEX (ONCOGENE PROTEIN/PEPTIDE) 1csk    PHOSPHOTRANSFERASE 1csy    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1csz    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1cwd    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1cwe    COMPLEX (PHOSPHOTRANSFERASE/PEPTIDE) 1d1z    GENE REGULATION 1e6g    SH3-DOMAIN 1efn    COMPLEX (SH3 DOMAIN/VIRAL ENHANCER) 1f1w    TRANSFERASE 1f2f    TRANSFERASE 1fbz    TRANSFERASE 1fgi    PROTEIN KINASE 1fgk    PHOSPHOTRANSFERASE 1fhs    SH2 DOMAIN 1fmk    PHOSPHOTRANSFERASE 1fpu    TRANSFERASE 1fu5    PEPTIDE BINDING PROTEIN 1fu6    PROTEIN BINDING 1fvr    TRANSFERASE 1fyn    TRANSFERASE 1fyr    HORMONE/GROWTH FACTOR 1g2b    METAL BINDING PROTEIN 1g83    TRANSFERASE 1gag    TRANSFERASE, SIGNALING PROTEIN 1ghu    SRC HOMOLOGY 2 DOMAIN 1gjo    TRANSFERASE 1gl5    TRANSFERASE 1h3h    COMPLEX (SH3/PEPTIDE) 1h92    TRANSFERASE 1h9o    COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR) 1hcs    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1hct    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1hd3    CYTOSKELETON 1hsq    PHOSPHORIC DIESTER HYDROLASE 1i3z    SIGNALING PROTEIN 1i44    TRANSFERASE 1ias    TRANSFERASE 1iep    TRANSFERASE 1ijr    TRANSFERASE/SIGNALING PROTEIN 1ir3    COMPLEX (TRANSFERASE/SUBSTRATE) 1irk    TRANSFERASE (PHOSPHOTRANSFERASE) 1is0    TRANSFERASE 1jeg    TRANSFERASE/HYDROLASE 1jpa    TRANSFERASE 1jqh    TRANSFERASE 1jqq    PROTEIN TRANSPORT, MEMBRANE PROTEIN 1ju5    PROTEIN BINDING/TRANSFERASE 1jwo    TRANSFERASE 1jyq    SIGNALING PROTEIN 1jyr    SIGNALING PROTEIN 1jyu    SIGNALING PROTEIN 1k2p    TRANSFERASE 1k3a    TRANSFERASE 1k9a    TRANSFERASE 1kc2    TRANSFERASE 1kik    TRANSFERASE 1ksw    TRANSFERASE 1lcj    COMPLEX (KINASE/PEPTIDE) 1lck    COMPLEX (KINASE/PEPTIDE) 1lkk    COMPLEX (TYROSINE KINASE/PEPTIDE) 1lkl    COMPLEX (TYROSINE KINASE/PEPTIDE) 1luf    TRANSFERASE 1lui    TRANSFERASE 1luk    TRANSFERASE 1lum    TRANSFERASE 1lun    TRANSFERASE 1m14    TRANSFERASE 1m17    TRANSFERASE 1m27    SIGNALING PROTEIN, TRANSFERASE 1m30    PROTEIN BINDING 1m3a    PROTEIN BINDING 1m3b    PROTEIN BINDING 1m3c    PROTEIN BINDING 1m52    TRANSFERASE 1m7n    TRANSFERASE 1m8m    STRUCTURAL PROTEIN 1mil    TRANSFORMING PROTEIN 1mp8    TRANSFERASE 1mqb    TRANSFERASE 1mw4    HORMONE/GROWTH FACTOR/TRANSFERASE 1n5z    PROTEIN TRANSPORT 1nlo    COMPLEX (TRANSFERASE/PEPTIDE) 1nlp    COMPLEX (TRANSFERASE/PEPTIDE) 1nm7    PROTEIN TRANSPORT 1nyf    PHOSPHOTRANSFERASE 1nyg    PHOSPHOTRANSFERASE 1nzl    TRANSFERASE 1nzv    TRANSFERASE 1o41    SIGNALING PROTEIN 1o42    SIGNALING PROTEIN 1o43    SIGNALING PROTEIN 1o44    SIGNALING PROTEIN 1o45    SIGNALING PROTEIN 1o46    SIGNALING PROTEIN 1o47    SIGNALING PROTEIN 1o48    SIGNALING PROTEIN 1o49    SIGNALING PROTEIN 1o4a    SIGNALING PROTEIN 1o4b    SIGNALING PROTEIN 1o4c    SIGNALING PROTEIN 1o4d    SIGNALING PROTEIN 1o4e    SIGNALING PROTEIN 1o4f    SIGNALING PROTEIN 1o4g    SIGNALING PROTEIN 1o4h    SIGNALING PROTEIN 1o4i    SIGNALING PROTEIN 1o4j    SIGNALING PROTEIN 1o4k    SIGNALING PROTEIN 1o4l    SIGNALING PROTEIN 1o4m    SIGNALING PROTEIN 1o4n    SIGNALING PROTEIN 1o4o    SIGNALING PROTEIN 1o4p    SIGNALING PROTEIN 1o4q    SIGNALING PROTEIN 1o4r    SIGNALING PROTEIN 1oeb    SH3 DOMAIN/COMPLEX 1oec    TRANSFERASE 1oo3    PROTEIN BINDING 1oo4    PROTEIN BINDING 1opj    TRANSFERASE 1opk    TRANSFERASE 1opl    TRANSFERASE 1p13    TRANSFERASE 1p14    TRANSFERASE 1p4o    HORMONE/GROWTH FACTOR 1pic    COMPLEX (PHOSPHOTRANSFERASE/RECEPTOR) 1pkg    TRANSFERASE ACTIVATOR 1prl    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1prm    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1pwt    CIRCULAR PERMUTANT 1qcf    TYROSINE KINASE 1qg1    HORMONE/GROWTH FACTOR 1qkw    CYTOSKELETON 1qkx    CYTOSKELETON 1qly    TYROSINE-PROTEIN KINASE 1qpc    TRANSFERASE 1qpd    TRANSFERASE 1qpe    TRANSFERASE 1qpj    TRANSFERASE 1qwe    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1qwf    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1r0p    TRANSFERASE 1rja    TRANSFERASE 1rjb    TRANSFERASE 1rlp    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1rlq    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1rqq    TRANSFERASE/SIGNALING PROTEIN 1sha    PHOSPHOTRANSFERASE 1shb    PHOSPHOTRANSFERASE 1shd    COMPLEX(TRANSFERASE/PEPTIDE) 1shf    PHOSPHOTRANSFERASE 1shg    CYTOSKELETON 1skj    TYROSINE-PROTEIN KINASE 1sm2    TRANSFERASE 1snu    TRANSFERASE 1snx    TRANSFERASE 1spr    TRANSFERASE(PHOSPHOTRANSFERASE) 1sps    TRANSFERASE(PHOSPHOTRANSFERASE) 1srl    PHOSPHOTRANSFERASE 1srm    PHOSPHOTRANSFERASE 1t45    TRANSFERASE ACTIVATOR 1t46    TRANSFERASE ACTIVATOR 1tce    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1tud    CYTOSKELETON 1tze    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1u46    TRANSFERASE 1u4d    TRANSFERASE 1u54    TRANSFERASE 1u59    TRANSFERASE 1udl    ENDOCYTOSIS/EXOCYTOSIS 1uhc    STRUCTURAL GENOMICS, UNKNOWN FUNCTION 1uhf    SIGNALING PROTEIN 1uti    SH3 DOMAIN/COMPLEX 1uue    SH3-DOMAIN 1uwh    KINASE 1uwj    KINASE 1vjy    TRANSFERASE 1vr2    TRANSFERASE 1w1f    SH3-DOMAIN 1wa7    SH3 DOMAIN 1wxu    PROTEIN TRANSPORT 1x0n    PEPTIDE BINDING PROTEIN 1x27    SIGNALING PROTEIN 1x2k    SIGNALING PROTEIN 1x2p    TRANSFERASE 1xba    TRANSFERASE 1xbb    TRANSFERASE 1xbc    TRANSFERASE 1xkk    TRANSFERASE 1y57    TRANSFERASE 1yi6    TRANSFERASE 1yoj    TRANSFERASE 1yol    TRANSFERASE 1yom    TRANSFERASE 1ywn    TRANSFERASE 1z3k    STRUCTURAL GENOMICS, UNKNOWN FUNCTION 1zbj    TRANSFERASE 1zfp    COMPLEX (SIGNAL TRANSDUCTION/PEPTIDE) 1zlm    SIGNALING PROTEIN 1zsg    TRANSFERASE 2a08    PROTEIN BINDING 2a37    SIGNALING PROTEIN 2abl    TRANSFERASE 2ak5    ENDOCYTOSIS/EXOCYTOSIS 2aoa    TRANSFERASE 2aob    TRANSFERASE 2aug    SIGNALING PROTEIN 2auh    TRANSFERASE/SIGNALING PROTEIN 2azv    SIGNALING PROTEIN 2bdf    TRANSFERASE 2bdj    TRANSFERASE 2c0i    TRANSFERASE 2c0o    TRANSFERASE 2c0t    TRANSFERASE 2c9w    TRANSCRIPTION REGULATION 2cdt    STRUCTURAL PROTEIN 2cia    SH2-DOMAIN 2cuc    SIGNALING PROTEIN 2cud    SIGNALING PROTEIN 2d0n    SIGNALING PROTEIN 2d8h    UNKNOWN FUNCTION 2d8j    TRANSFERASE 2df6    SIGNALING PROTEIN 2dly    TRANSFERASE 2dlz    SIGNALING PROTEIN 2dm0    TRANSFERASE 2dq7    TRANSFERASE 2dx0    HYDROLASE 2e2b    TRANSFERASE 2eb2    TRANSFERASE 2eb3    TRANSFERASE 2ecd    SIGNALING PROTEIN 2ekx    SIGNALING PROTEIN 2eo3    SIGNALING PROTEIN 2eob    HYDROLASE 2eqi    IMMUNE SYSTEM, HYDROLASE 2esw    SIGNALING PROTEIN 2etm    TRANSFERASE 2etz    TRANSFERASE 2eu0    TRANSFERASE 2eva    TRANSFERASE/TRANSFERASE ACTIVATOR 2eyv    SIGNALING PROTEIN 2eyw    SIGNALING PROTEIN 2f2v    SIGNALING PROTEIN 2f2w    SIGNALING PROTEIN 2f4j    TRANSFERASE 2fb8    TRANSFERASE 2fgi    TRANSFERASE 2fo0    TRANSFERASE 2fry    PROTEIN BINDING 2g15    TRANSFERASE 2g1t    TRANSFERASE 2g2f    TRANSFERASE 2g2h    TRANSFERASE 2g2i    TRANSFERASE 2g6f    SIGNALING PROTEIN 2ge9    TRANSFERASE 2gqg    TRANSFERASE 2gs2    TRANSFERASE 2gs6    TRANSFERASE 2gs7    TRANSFERASE 2gsf    TRANSFERASE 2h46    HORMONE/GROWTH FACTOR 2h5k    HORMONE/GROWTH FACTOR 2h8h    TRANSFERASE 2hck    TRANSFERASE 2hda    TRANSFERASE 2hel    SIGNALING PROTEIN, TRANSFERASE 2hen    TRANSFERASE 2hiw    TRANSFERASE 2hk5    TRANSFERASE 2hsp    PHOSPHORIC DIESTER HYDROLASE 2huw    HORMONE/GROWTH FACTOR 2hwo    TRANSFERASE 2hwp    TRANSFERASE 2hyy    TRANSFERASE 2hz0    TRANSFERASE 2hz4    TRANSFERASE 2hzi    TRANSFERASE 2hzn    TRANSFERASE 2i0v    TRANSFERASE 2i0y    TRANSFERASE 2i1m    TRANSFERASE 2iim    SIGNALING PROTEIN 2ijm    SIGNALING PROTEIN,TRANSFERASE 2itn    TRANSFERASE 2ito    TRANSFERASE 2itp    TRANSFERASE 2itq    TRANSFERASE 2itu    TRANSFERASE 2itw    TRANSFERASE 2itx    TRANSFERASE 2ity    TRANSFERASE 2itz    TRANSFERASE 2iug    TRANSFERASE 2iui    TRANSFERASE 2ivs    TRANSFERASE 2ivt    TRANSFERASE 2ivu    TRANSFERASE 2ivv    TRANSFERASE 2j0j    TRANSFERASE 2j0k    TRANSFERASE 2j0l    TRANSFERASE 2j0m    TRANSFERASE 2j5e    TRANSFERASE 2j5f    TRANSFERASE 2j6m    TRANSFERASE 2jkk    TRANSFERASE 2jkm    TRANSFERASE 2jko    TRANSFERASE 2jkq    TRANSFERASE 2jm8    STRUCTURAL PROTEIN 2jm9    STRUCTURAL PROTEIN 2jma    STRUCTURAL PROTEIN 2js2    SIGNALING PROTEIN 2jw4    SIGNALING PROTEIN 2jyq    TRANSFERASE 2o88    SIGNALING PROTEIN 2of2    TRANSFERASE 2of4    TRANSFERASE 2ofu    TRANSFERASE 2ofv    TRANSFERASE 2og8    TRANSFERASE 2ogv    TRANSFERASE 2oh4    TRANSFERASE 2oi3    TRANSFERASE 2oiq    TRANSFERASE 2oj2    SIGNALING PROTEIN,TRANSFERASE/INHIBITOR 2oj9    TRANSFERASE 2oo8    TRANSFERASE 2osc    TRANSFERASE 2ozo    TRANSFERASE 2p0c    TRANSFERASE 2p2h    TRANSFERASE 2p4i    TRANSFERASE 2p4r    LIGASE 2pl0    TRANSFERASE 2pna    SIGNALLING PROTEIN 2pnb    SIGNALLING PROTEIN 2pqh    STRUCTURAL PROTEIN 2psq    TRANSFERASE 2ptk    TYROSINE-PROTEIN KINASE 2pvf    TRANSFERASE 2pvy    TRANSFERASE 2pwl    TRANSFERASE 2py3    TRANSFERASE 2q0b    TRANSFERASE 2qi8    SIGNALING PROTEIN, TRANSFERASE 2qlq    TRANSFERASE 2qms    SIGNALING PROTEIN 2qo2    TRANSFERASE 2qo7    TRANSFERASE 2qo9    TRANSFERASE 2qob    TRANSFERASE 2qoc    TRANSFERASE 2qod    TRANSFERASE 2qof    TRANSFERASE 2qoh    TRANSFERASE 2qoi    TRANSFERASE 2qok    TRANSFERASE 2qol    TRANSFERASE 2qon    TRANSFERASE 2qoo    TRANSFERASE 2qoq    TRANSFERASE 2qq7    TRANSFERASE 2qu5    TRANSFERASE 2qu6    TRANSFERASE 2r2p    TRANSFERASE 2r4b    TRANSFERASE 2rei    TRANSFERASE 2rf0    TRANSFERASE 2rf9    TRANSFERASE 2rfs    TRANSFERASE 2rgp    TRANSFERASE 2rl5    TRANSFERASE 2rmo    SIGNALING PROTEIN 2src    TYROSINE-PROTEIN KINASE 2v1r    PROTEIN TRANSPORT 2v7a    TRANSFERASE 2vkn    MEMBRANE PROTEIN 2vwu    TRANSFERASE 2vwv    TRANSFERASE 2vww    TRANSFERASE 2vwx    TRANSFERASE 2vwy    TRANSFERASE 2vwz    TRANSFERASE 2vx0    TRANSFERASE 2vx1    TRANSFERASE 2ysx    SIGNALING PROTEIN 2yt6    CELL CYCLE 2z60    TRANSFERASE 2z8c    TRANSFERASE 2zm1    TRANSFERASE 2zm3    TRANSFERASE 2zm4    TRANSFERASE 2zv7    TRANSFERASE 2zv8    TRANSFERASE 2zv9    TRANSFERASE 2zva    TRANSFERASE 2zyb    TRANSFERASE 3b2t    TRANSFERASE 3b2w    TRANSFERASE 3b8r    TRANSFERASE 3bbt    TRANSFERASE 3bbw    TRANSFERASE 3bce    TRANSFERASE 3be2    TRANSFERASE 3bea    TRANSFERASE 3bel    TRANSFERASE 3bkb    TRANSFERASE 3bpr    TRANSFERASE 3brb    TRANSFERASE 3bu3    TRANSFERASE 3bu5    TRANSFERASE 3bu6    TRANSFERASE 3bym    TRANSFERASE 3byo    TRANSFERASE 3bys    TRANSFERASE 3byu    TRANSFERASE 3bz3    TRANSFERASE 3c4c    TRANSFERASE 3c4d    TRANSFERASE 3c4f    TRANSFERASE 3c7i    SPLICING 3c7q    TRANSFERASE 3cbl    TRANSFERASE 3cc6    TRANSFERASE 3ccn    TRANSFERASE 3cd3    TRANSFERASE 3cd8    TRANSFERASE 3cjf    TRANSFERASE 3cjg    TRANSFERASE 3cly    TRANSFERASE 3cpb    TRANSFERASE 3cpc    TRANSFERASE 3cqt    TRANSFERASE 3cs9    TRANSFERASE 3d4q    TRANSFERASE 3d7t    TRANSFERASE 3d7u    TRANSFERASE 3d94    TRANSFERASE 3dk3    TRANSFERASE 3dk6    TRANSFERASE 3dk7    TRANSFERASE 3dko    TRANSFERASE 3dqw    TRANSFERASE 3dqx    TRANSFERASE 3dzq    TRANSFERASE 3efk    TRANSFERASE 3ekk    TRANSFERASE 3ekn    TRANSFERASE 3el7    TRANSFERASE 3el8    TRANSFERASE 3emg    TRANSFERASE 3en4    TRANSFERASE 3en5    TRANSFERASE 3en6    TRANSFERASE 3en7    TRANSFERASE 3eqp    TRANSFERASE 3eqr    TRANSFERASE 3eyg    TRANSFERASE 3eyh    TRANSFERASE 3f5p    TRANSFERASE 3f66    TRANSFERASE 3f6x    TRANSFERASE 3faa    TRANSFERASE 3fxx    TRANSFERASE 3fy2    TRANSFERASE 3hck    TRANSFERASE 3lck    TYROSINE-PROTEIN KINASE 4hck    TRANSFERASE 5hck    TRANSFERASE PSSH: ID    Description Q71UK5    UNKNOWN Q76P87    UNKNOWN Q9H7V3    UNKNOWN P12931    UNKNOWN
Diseases	OMIM: OMIM ID    Name    Alt Name 190090    V-SRC AVIAN SARCOMA (SCHMIDT-RUPPIN A-2) VIRAL ONCOGENE; SRC    ONCOGENE SRC PROTOONCOGENE SRC SRC ONCOGENE AVIAN SARCOMA VIRUS; ASV
Gene Ontology	GO: GO ID    Description GO:0000166    nucleotide binding GO:0001101    response to acid GO:0004672    protein kinase activity GO:0004674    protein serine/threonine kinase activity GO:0004713    protein tyrosine kinase activity GO:0004715    non-membrane spanning protein tyrosine kinase activity GO:0005070    SH3/SH2 adaptor activity GO:0005515    protein binding GO:0005524    ATP binding GO:0005829    cytosol GO:0005886    plasma membrane GO:0005901    caveola GO:0006468    protein amino acid phosphorylation GO:0006950    response to stress GO:0007172    signal complex assembly GO:0007173    epidermal growth factor receptor signaling pathway GO:0007243    protein kinase cascade GO:0007265    Ras protein signal transduction GO:0008022    protein C-terminus binding GO:0008283    cell proliferation GO:0016301    kinase activity GO:0016337    cell-cell adhesion GO:0016477    cell migration GO:0016740    transferase activity GO:0018108    peptidyl-tyrosine phosphorylation GO:0019904    protein domain specific binding GO:0030900    forebrain development GO:0042169    SH2 domain binding GO:0043065    positive regulation of apoptosis GO:0044419    interspecies interaction between organisms GO:0045056    transcytosis GO:0045785    positive regulation of cell adhesion GO:0046628    positive regulation of insulin receptor signaling pathway GO:0048008    platelet-derived growth factor receptor signaling pathway GO:0048011    nerve growth factor receptor signaling pathway GO:0051385    response to mineralocorticoid stimulus
Pathway	KEGG: KEGG PATHWAY ID    Name hsa04520    Adherens junction hsa04144    Endocytosis hsa05120    Epithelial cell signaling in Helicobacter pylori infection hsa04012    ErbB signaling pathway hsa04510    Focal adhesion hsa04540    Gap junction hsa04912    GnRH signaling pathway hsa04530    Tight junction hsa04370    VEGF signaling pathway Panther: ID    Description P00049    Parkinson disease P00034    Integrin signalling pathway P00012    Cadherin signaling pathway P00005    Angiogenesis
Chemicals	DrugBank: ID    Name    Synonyms DB01254    Dasatinib    BMS-354825; dasatinib DB01893    N6-Benzyl Adenosine-5'-Diphosphate    DB01678    RU84687    N-acetyl-N-[1-(1,1'-biphenyl-4-ylmethyl)-2-oxoazepan-3-yl]-3-formyl-O-phosphonotyrosinamide DB04739    4-[(4-METHYL-1-PIPERAZINYL)METHYL]-N-[3-[[4-(3-PYRIDINYL)-2-PYRIMIDINYL]AMINO]PHENYL]-BENZAMIDE    DB04751    Purvalanol A    6-((3-chloro)anilino)-2-(isopropyl-2-hydroxyethylamino)-9-isopropylpurine; Purv DB01962    Phosphonotyrosine    HMDB: ID    Name    Synonyms
Orthology	Orthology Relations: Gene Gene Description Organism Orthology type Orthologs Orthologs Description ENSG00000197122 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931] Pan_troglodytes one2one ENSPTRG00000013474 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]SRC Pongo_pygmaeus one2one ENSPPYG00000010985 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Macaca_mulatta one2one ENSMMUG00000020131 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Microcebus_murinus one2one ENSMICG00000005684 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Myotis_lucifugus one2one ENSMLUG00000004480 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Tursiops_truncatus one2one ENSTTRG00000005695 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Pteropus_vampyrus one2one ENSPVAG00000017785 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Felis_catus one2one ENSFCAG00000006991 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Bos_taurus one2one ENSBTAG00000008938 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]SRC Cavia_porcellus one2one ENSCPOG00000011012 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Procavia_capensis one2one ENSPCAG00000005712 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Canis_familiaris one2one ENSCAFG00000008755 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]SRC Echinops_telfairi one2one ENSETEG00000007521 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Erinaceus_europaeus one2one ENSEEUG00000005742 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Equus_caballus one2one ENSECAG00000012072 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Otolemur_garnettii one2one ENSOGAG00000015510 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Ochotona_princeps one2one ENSOPRG00000012428 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Dipodomys_ordii one2one ENSDORG00000016279 Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P05480][hgnc] Mus_musculus one2one ENSMUSG00000027646 Neuronal proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P05480][hgnc]Src Rattus_norvegicus one2one ENSRNOG00000009495 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src). [Source:UniProtKB/Swiss-Prot;Acc:Q9WUD9][hgnc]Src Gallus_gallus one2one ENSGALG00000003855 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (p60-Src) (c- Src) (pp60c-src). [Source:UniProtKB/Swiss-Prot;Acc:P00523][hgnc]SRC Monodelphis_domestica one2one ENSMODG00000000247 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Xenopus_tropicalis one2one ENSXETG00000017318 C-src tyrosine kinase. [Source:UniProtKB/TrEMBL;Acc:Q5MAS9][hgnc] Danio_rerio one2one ENSDARG00000008107 protein-tyrosine kinase [Source:RefSeq_peptide;Acc:NP_001003837][hgnc]LOC555652 Gasterosteus_aculeatus one2many ENSGACG00000011349 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Oryzias_latipes one2many ENSORLG00000016183 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Takifugu_rubripes one2many ENSTRUG00000005980 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Tetraodon_nigroviridis one2many ENSTNIG00000019527 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Gasterosteus_aculeatus one2many ENSGACG00000005548 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Tetraodon_nigroviridis one2many ENSTNIG00000018270 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Oryzias_latipes one2many ENSORLG00000006714 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc] Takifugu_rubripes one2many ENSTRUG00000018366 Proto-oncogene tyrosine-protein kinase Src (EC 2.7.10.2) (pp60c-src) (p60-Src) (c-Src) [Source:UniProtKB/Swiss-Prot;Acc:P12931][hgnc]