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Summary sheet information for GPCR 'OLFACTORY RECEPTORS_OR4E2_Homo sapiens'
Name OLFACTORY RECEPTORS_OR4E2_Homo sapiens
Description RecName: Full=Olfactory receptor 4E2;AltName: Full=Olfactory receptor OR14-42
Class CLASS A
Family OLFACTORY RECEPTORS
Sub_family OR4E2
type
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 14
Gene Start: 21203137
Gene End: 21204078
Ensembl Contig View
Ensembl Genes:
ENSG00000221977
EMBL:
EMBL ID  Description
AB065895  Homo sapiens gene for seven transmembrane helix receptor, complete cds, isolate:CBRC7TM_458.
AF399581  Homo sapiens clone OR4E2 olfactory receptor gene, partial cds.
BK004526  TPA: Homo sapiens olfactory receptor OR14-42 gene, complete cds.

EntrezGene:
ID  Description
OR4E2  olfactory receptor, family 4, subfamily E, member 2
RefSeq DNA:
ID  Description
NM_001001912  Homo sapiens olfactory receptor, family 4, subfamily E, member 2 (OR4E2), mRNA.

UniGene:
ID  Description
Hs.547982  Clone MO-28 mRNA sequence

Proteins
Ensembl Proteins:
ENSP00000386195
Entrez Proteins:
AAK95066.1; BAC06111.1; DAA04924.1
RefSeq Proteins:
ID  Description
NP_001001912  olfactory receptor, family 4, subfamily E, member 2 [Homo sapiens].

UniProt:
ID  Description
Q8NGC2  RecName: Full=Olfactory receptor 4E2; AltName: Full=Olfactory receptor OR14-42;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR000725  Olfact_rcpt
IPR000276  GPCR_Rhodpsn
IPR017452  GPCR_Rhodpsn_supfam
Pfam:
ID  Description
7tm_1  7 transmembrane receptor (rhodopsin family)

Structure
PDB:
ID
HSSP:
ID  Description
PSSH:
ID  Description
Diseases
OMIM:
OMIM ID  Name  Alt Name
Gene Ontology
GO:
GO ID  Description
GO:0001584  rhodopsin-like receptor activity
GO:0004872  receptor activity
GO:0004930  G-protein coupled receptor activity
GO:0004977  melanocortin receptor activity
GO:0004984  olfactory receptor activity
GO:0005886  plasma membrane
GO:0007165  signal transduction
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007608  sensory perception of smell
GO:0016021  integral to membrane
GO:0050896  response to stimulus
Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04740  Olfactory transduction

Panther:
ID  Description
Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Other GPCR resources
Links to other GPCR resources
GPCRDB | GPCR-OKB | GLIDA
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000221977 Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2] Pongo_pygmaeusone2one ENSPPYG00000005606Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2][hgnc]
Equus_caballusone2one ENSECAG00000002752Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2][hgnc]LOC100059491
Felis_catusone2one ENSFCAG00000019253Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2][hgnc]
Bos_taurusone2one ENSBTAG00000007029Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2][hgnc]LOC513435
Rattus_norvegicusone2one ENSRNOG00000013338olfactory receptor Olr1643 [Source:RefSeq_peptide;Acc:NP_001000535][hgnc]Olr1643_predicted
Mus_musculusone2one ENSMUSG00000035626odorant receptor MOR83 [Source:RefSeq_peptide;Acc:NP_065260][hgnc]Olfr1509
Cavia_porcellusone2one ENSCPOG00000026054Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2][hgnc]
Canis_familiarisone2one ENSCAFG00000005679Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2][hgnc]
Monodelphis_domesticaone2one ENSMODG00000005980Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000010758Olfactory receptor 4E2 (Olfactory receptor OR14-42) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGC2][hgnc]100087699