Human-gpDB    A database of human GPCRs, G-proteins, Effectors and their interactions

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	Summary sheet information for Effector 'Tubulin-Homo sapiens-26'
Name	Tubulin-Homo sapiens-26
Description	RecName: Full=Gamma-tubulin complex component 5; Short=GCP-5
Class
Family	Tubulins
Sub_family	Tubulins
type	Tubulin
Protein features link	Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction	Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes	Gene Location: Chromosome : 15 Gene Start : 20384836 Gene End : 20425331 Ensembl Contig View Ensembl Genes: ENSG00000153575 EMBL: EMBL ID    Description AB067486    Homo sapiens mRNA for KIAA1899 protein, partial cds. AF272884    Homo sapiens gamma-tubulin complex component GCP5 (GCP5) mRNA, complete cds. AK289859    Homo sapiens cDNA FLJ77411 complete cds, highly similar to Homo sapiens gamma-tubulin complex component GCP5 (GCP5) mRNA. BC046182    Homo sapiens tubulin, gamma complex associated protein 5, mRNA (cDNA clone IMAGE:5175880), complete cds. BC071560    Homo sapiens tubulin, gamma complex associated protein 5, mRNA (cDNA clone MGC:86996 IMAGE:5297149), complete cds. EntrezGene: ID    Description TUBGCP5    tubulin, gamma complex associated protein 5 RefSeq DNA: ID    Description NM_001102610    Homo sapiens tubulin, gamma complex associated protein 5 (TUBGCP5), transcript variant 2, mRNA. NM_052903    Homo sapiens tubulin, gamma complex associated protein 5 (TUBGCP5), transcript variant 1, mRNA. UniGene: ID    Description Hs.533898    Tubulin, gamma complex associated protein 5 (TUBGCP5), transcript variant 1, mRNA
Proteins	Ensembl Proteins: ENSP00000283645 Entrez Proteins: AAH46182.1; AAH71560.1; AAK77662.1; BAB67792.2; BAF82548.1 RefSeq Proteins: ID    Description NP_001096080    tubulin, gamma complex associated protein 5 isoform b [Homo sapiens]. NP_443135    tubulin, gamma complex associated protein 5 isoform a [Homo sapiens]. UniProt: ID    Description A8K1E4    SubName: Full=cDNA FLJ77411, highly similar to Homo sapiens gamma-tubulin complex component GCP5 (GCP5) mRNA; Q96RT8    RecName: Full=Gamma-tubulin complex component 5; Short=GCP-5;
Domains	SMART: - Hyperlink to SMART; - Hyperlink to ENSEMBL InterPro: ID    Name IPR007259    Spc97_Spc98 Pfam: ID    Description Spc97_Spc98    Spc97 / Spc98 family
Structure	PDB: ID HSSP: ID    Description PSSH: ID    Description
Diseases	OMIM: OMIM ID    Name    Alt Name 608147    TUBULIN-GAMMA COMPLEX-ASSOCIATED PROTEIN 5; TUBGCP5    TUBG COMPLEX-ASSOCIATED PROTEIN 5 GAMMA-TUBULIN COMPLEX COMPONENT 5; GCP5 KIAA1899
Gene Ontology	GO: GO ID    Description GO:0000226    microtubule cytoskeleton organization GO:0000922    spindle pole GO:0005813    centrosome GO:0005815    microtubule organizing center GO:0005874    microtubule GO:0007020    microtubule nucleation GO:0008017    microtubule binding GO:0008274    gamma-tubulin ring complex
Pathway	KEGG: KEGG PATHWAY ID    Name Panther: ID    Description
Chemicals	DrugBank: ID    Name    Synonyms HMDB: ID    Name    Synonyms
Orthology	Orthology Relations: Gene Gene Description Organism Orthology type Orthologs Orthologs Description ENSG00000153575 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8] Pan_troglodytes one2one ENSPTRG00000006817 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Pongo_pygmaeus one2one ENSPPYG00000006257 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Macaca_mulatta one2one ENSMMUG00000005533 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Microcebus_murinus one2one ENSMICG00000012969 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Tarsius_syrichta one2one ENSTSYG00000003897 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Otolemur_garnettii one2one ENSOGAG00000014141 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Equus_caballus one2one ENSECAG00000005538 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Tursiops_truncatus one2one ENSTTRG00000006189 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Dasypus_novemcinctus one2one ENSDNOG00000002996 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Spermophilus_tridecemlineatus one2one ENSSTOG00000000167 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Felis_catus one2one ENSFCAG00000004965 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Canis_familiaris one2one ENSCAFG00000009579 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc]TUBGCP5 Oryctolagus_cuniculus one2one ENSOCUG00000010715 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Bos_taurus one2one ENSBTAG00000014714 TUBGCP5 protein. [Source:UniProtKB/TrEMBL;Acc:A6H7H5][hgnc] Dipodomys_ordii one2one ENSDORG00000011370 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q8BKN5][hgnc] Pteropus_vampyrus one2one ENSPVAG00000012593 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Myotis_lucifugus one2one ENSMLUG00000011065 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Vicugna_pacos one2one ENSVPAG00000010034 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Mus_musculus one2one ENSMUSG00000033790 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q8BKN5][hgnc]Tubgcp5 Rattus_norvegicus one2one ENSRNOG00000011480 tubulin, gamma complex associated protein 5 [Source:RefSeq_peptide;Acc:NP_001100986][hgnc]Tubgcp5_predicted Procavia_capensis one2one ENSPCAG00000011761 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Erinaceus_europaeus one2one ENSEEUG00000000402 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Ochotona_princeps one2one ENSOPRG00000010432 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Echinops_telfairi one2one ENSETEG00000012870 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Sorex_araneus one2one ENSSARG00000010057 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Cavia_porcellus one2one ENSCPOG00000008054 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Monodelphis_domestica one2one ENSMODG00000000525 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Tupaia_belangeri one2one ENSTBEG00000010652 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Gallus_gallus one2one ENSGALG00000016735 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Xenopus_tropicalis one2one ENSXETG00000004137 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Gasterosteus_aculeatus one2one ENSGACG00000013824 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Oryzias_latipes one2one ENSORLG00000016018 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Tetraodon_nigroviridis one2one ENSTNIG00000001039 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc] Takifugu_rubripes one2one ENSTRUG00000010285 Gamma-tubulin complex component 5 (GCP-5) [Source:UniProtKB/Swiss-Prot;Acc:Q96RT8][hgnc]