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Description Entry page for Effector - 'Phosphodiesterase 1A-Homo sapiens'
FamilyPhosphodiesterases
Sub-FamilyCalmodium/calcium-dependent PDEases
TypePhosphodiesterase 1A
Cross References:
References
UniProtP54750 | Q86VZ0 | Q9C0K8 | Q9C0K9 | Q9C0L0 | Q9C0L1 | Q9C0L2 | Q9C0L3
EMBLU40370 | AB038224 | AB038224 | AB038224 | AB038224 | AB038224 | AB038224 | AB038224 | AB038224 | AB038224 | AJ401610 | AL110263 | BC022480
InterProIPR003607 | IPR002073 | IPR013706
PRODOM
GENEID5136
MIM171890
PRINTSPR00387
PFAMPF00233 | PF08499
Details:
Details
NamePhosphodiesterase 1A-Homo sapiens
Description"RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A; Short=Cam-PDE 1A; EC=3.1.4.17;AltName: Full=61 kDa Cam-PDE; Short=hCam-1;"
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GenePDE1
FunctionHas a higher affinity for cGMP than for cAMP
Fragment0
Sequence
MGSSATEIEELENTTFKYLTGEQTEKMWQRLKGILRCLVKQLERGDVNVVDLKKNIEYAA
SVLEAVYIDETRRLLDTEDELSDIQTDSVPSEVRDWLASTFTRKMGMTKKKPEEKPKFRS
IVHAVQAGIFVERMYRKTYHMVGLAYPAAVIVTLKDVDKWSFDVFALNEASGEHSLKFMI
YELFTRYDLINRFKIPVSCLITFAEALEVGYSKYKNPYHNLIHAADVTQTVHYIMLHTGI
MHWLTELEILAMVFAAAIHDYEHTGTTNNFHIQTRSDVAILYNDRSVLENHHVSAAYRLM
QEEEMNILINLSKDDWRDLRNLVIEMVLSTDMSGHFQQIKNIRNSLQQPEGIDRAKTMSL
ILHAADISHPAKSWKLHYRWTMALMEEFFLQGDKEAELGLPFSPLCDRKSTMVAQSQIGF
IDFIVEPTFSLLTDSTEKIVIPLIEEASKAETSSYVASSSTTIVGLHIADALRRSNTKGS
MSDGSYSPDYSLAAVDLKSFKNNLVDIIQQNKERWKELAAQEARTSSQKCEFIHQ
Interacting with G-proteins:
G-proteins
NoNameRegulationPubMed
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level