Quick search:







Description Entry page for Effector - 'Phosphodiesterase 1B-Homo sapiens'
FamilyPhosphodiesterases
Sub-FamilyCalmodium/calcium-dependent PDEases
TypePhosphodiesterase 1B
Cross References:
References
UniProtQ01064 | Q92825
EMBLU56976 | U86078 | BC032226 | M94539
InterProIPR003607 | IPR002073 | IPR013706
PRODOM
GENEID5153
MIM171891
PRINTSPR00387
PFAMPF00233 | PF08499
Details:
Details
NamePhosphodiesterase 1B-Homo sapiens
Description"RecName: Full=Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B; Short=Cam-PDE 1B; EC=3.1.4.17;AltName: Full=63 kDa Cam-PDE;"
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GenePDE1B | PDE1B1,PDES1
FunctionHas a preference for cGMP as a substrate
Fragment0
Sequence
MELSPRSPPEMLEESDCPSPLELKSAPSKKMWIKLRSLLRYMVKQLENGEINIEELKKNL
EYTASLLEAVYIDETRQILDTEDELQELRSDAVPSEVRDWLASTFTQQARAKGRRAEEKP
KFRSIVHAVQAGIFVERMFRRTYTSVGPTYSTAVLNCLKNLDLWCFDVFSLNQAADDHAL
RTIVFELLTRHNLISRFKIPTVFLMSFLDALETGYGKYKNPYHNQIHAADVTQTVHCFLL
RTGMVHCLSEIELLAIIFAAAIHDYEHTGTTNSFHIQTKSECAIVYNDRSVLENHHISSV
FRLMQDDEMNIFINLTKDEFVELRALVIEMVLATDMSCHFQQVKTMKTALQQLERIDKPK
ALSLLLHAADISHPTKQWLVHSRWTKALMEEFFRQGDKEAELGLPFSPLCDRTSTLVAQS
QIGFIDFIVEPTFSVLTDVAEKSVQPLADEDSKSKNQPSFQWRQPSLDVEVGDPNPDVVS
FRSTWVKRIQENKQKWKERAASGITNQMSIDELSPCEEEAPPSPAEDEHNQNGNLD
Interacting with G-proteins:
G-proteins
NoNameRegulationPubMed
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level