| Description |
Entry page for Effector - 'Phosphodiesterase 4B-Homo sapiens'
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Cross References: |
| References |
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Details: |
| Details |
| Name | Phosphodiesterase 4B-Homo sapiens |
| Description | "RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4B; EC=3.1.4.17;AltName: Full=DPDE4;AltName: Full=PDE32;" |
| Species | Homo sapiens |
| Common Name | Human |
| NCBI Taxonomy | 9606 |
| Gene | PDE4B | DPDE |
| Function | May be involved in mediating central nervous systems effects of therapeutic agents ranging from antidepressants tos antiasthmatic and anti-inflammatory agents |
| Fragment | 0 |
| Sequence | MKKSRSVMTVMADDNVKDYFECSLSKSYSSSSNTLGIDLWRGRRCCSGNLQLPPLSQRQS
ERARTPEGDGISRPTTLPLTTLPSIAITTVSQECFDVENGPSPGRSPLDPQASSSAGLVL
HATFPGHSQRRESFLYRSDSDYDLSPKAMSRNSSLPSEQHGDDLIVTPFAQVLASLRSVR
NNFTILTNLHGTSNKRSPAASQPPVSRVNPQEESYQKLAMETLEELDWCLDQLETIQTYR
SVSEMASNKFKRMLNRELTHLSEMSRSGNQVSEYISNTFLDKQNDVEIPSPTQKDREKKK
KQQLMTQISGVKKLMHSSSLNNTSISRFGVNTENEDHLAKELEDLNKWGLNIFNVAGYSH
NRPLTCIMYAIFQERDLLKTFRISSDTFITYMMTLEDHYHSDVAYHNSLHAADVAQSTHV
LLSTPALDAVFTDLEILAAIFAAAIHDVDHPGVSNQFLINTNSELALMYNDESVLENHHL
AVGFKLLQEEHCDIFMNLTKKQRQTLRKMVIDMVLATDMSKHMSLLADLKTMVETKKVTS
SGVLLLDNYTDRIQVLRNMVHCADLSNPTKSLELYRQWTDRIMEEFFQQGDKERERGMEI
SPMCDKHTASVEKSQVGFIDYIVHPLWETWADLVQPDAQDILDTLEDNRNWYQSMIPQSP
SPPLDEQNRDCQGLMEKFQFELTLDEEDSEGPEKEGEGHSYFSSTKTLCVIDPENRDSLG
ETDIDIATEDKSPVDT
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Interacting with G-proteins: |
| G-proteins |
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| GPCR, G-protein, Effector interaction |
Visualizaton of GPCR, G-protein, Effector interaction at protein level
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