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Description Entry page for Effector - 'Synembryn(Ric8a)-Homo sapiens'
FamilyGuanine nucleotide exchange factors
Sub-FamilySynembryns
TypeSynembryn(Ric8a)
Cross References:
References
UniProtQ9NPQ8 | Q0P508 | Q2T9J1 | Q7Z352 | Q96EZ1 | Q96SZ2 | Q9H064 | Q9H5H3
EMBLAL136935 | AK022870 | AK027090 | AK027461 | AL390088 | BX538115 | BC011821 | BC111499 | BC121807 | BC121808
InterProIPR019318 | IPR008376
PRODOM
GENEID60626
MIM609146
PRINTSPR01802
PFAMPF10165
Details:
Details
NameSynembryn(Ric8a)-Homo sapiens
DescriptionRecName: Full=Synembryn-A;AltName: Full=Protein Ric-8A
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneRIC8
FunctionGuanine nucleotide exchange factor (GEF), which cans activate some, but not all, G-alpha proteins
Fragment0
Sequence
MEPRAVAEAVETGEEDVIMEALRSYNQEHSQSFTFDDAQQEDRKRLAELLVSVLEQGLPP
SHRVIWLQSVRILSRDRNCLDPFTSRQSLQALACYADISVSEGSVPESADMDVVLESLKC
LCNLVLSSPVAQMLAAEARLVVKLTERVGLYRERSFPHDVQFFDLRLLFLLTALRTDVRQ
QLFQELKGVRLLTDTLELTLGVTPEGNPPTLLPSQETERAMEILKVLFNITLDSIKGEVD
EEDAALYRHLGTLLRHCVMIATAGDRTEEFHGHAVNLLGNLPLKCLDVLLTLEPHGDSTE
FMGVNMDVIRALLIFLEKRLHKTHRLKESVAPVLSVLTECARMHRPARKFLKAQVLPPLR
DVRTRPEVGEMLRNKLVRLMTHLDTDVKRVAAEFLFVLCSESVPRFIKYTGYGNAAGLLA
ARGLMAGGRPEGQYSEDEDTDTDEYKEAKASINPVTGRVEEKPPNPMEGMTEEQKEHEAM
KLVTMFDKLSRNRVIQPMGMSPRGHLTSLQDAMCETMEQQLSSDPDSDPD
Interacting with G-proteins:
G-proteins
NoNameRegulationPubMed
1Galpha-q_Homo sapiensStimulates Gqa activation and steady-state GTPase activity in vitro16182515 | 12509430
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level