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Description Entry page for GPCR - 'GROWTH HORMONE-RELEASING HORMONE RECEPTORS_GHRHR_Homo sapiens'
ClassCLASS B
FamilyGROWTH HORMONE-RELEASING HORMONE RECEPTORS
Sub-FamilyGHRHR
Cross References:
References
UniProtQ02643 | Q99863
EMBLL01406 | L09237 | AB065701 | AY557192 | AC005155 | U42225 | U42222 | U42223 | U42224
InterProIPR017981 | IPR001879 | IPR003288 | IPR000832 | IPR017983
PRODOM
GENEID2692
MIM139191 | 262400
PRINTSPR01352 | PR00249
PFAMPF00002 | PF02793
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameGROWTH HORMONE-RELEASING HORMONE RECEPTORS_GHRHR_Homo sapiens
DescriptionRecName: Full=Growth hormone-releasing hormone receptor; Short=GHRH receptor;AltName: Full=GRF receptor; Short=GRFR;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGHRH
FunctionReceptor for GRF, coupled to G proteins which activates adenylyl cyclase
Fragment0
Sequence
MDRRMWGAHVFCVLSPLPTVLGHMHPECDFITQLREDESACLQAAEEMPNTTLGCPATWD
GLLCWPTAGSGEWVTLPCPDFFSHFSSESGAVKRDCTITGWSEPFPPYPVACPVPLELLA
EEESYFSTVKIIYTVGHSISIVALFVAITILVALRRLHCPRNYVHTQLFTTFILKAGAVF
LKDAALFHSDDTDHCSFSTVLCKVSVAASHFATMTNFSWLLAEAVYLNCLLASTSPSSRR
AFWWLVLAGWGLPVLFTGTWVSCKLAFEDIACWDLDDTSPYWWIIKGPIVLSVGVNFGLF
LNIIRILVRKLEPAQGSLHTQSQYWRLSKSTLFLIPLFGIHYIIFNFLPDNAGLGIRLPL
ELGLGSFQGFIVAILYCFLNQEVRTEISRKWHGHDPELLPAWRTRAKWTTPSRSAAKVLT
SMC
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-11_Homo sapiensGq/1114755130 | 8688086
2Galpha-14_Homo sapiensGq/1114755130 | 8688086
3Galpha-q_Homo sapiensGq/1114755130 | 8688086
4Galpha-15_Homo sapiensGq/1114755130 | 8688086
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level