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Description Entry page for GPCR - 'METABOTROPIC GLUTAMATE RECEPTORS_MGLU1_Homo sapiens'
ClassCLASS C
FamilyMETABOTROPIC GLUTAMATE RECEPTORS
Sub-FamilyMGLU1
Cross References:
References
UniProtQ13255 | B9EG79 | Q13256 | Q14757 | Q14758 | Q5VTF7 | Q5VTF8 | Q9NU10
EMBLU31215 | U31216 | L76627 | L76631 | AL592423 | AL035698 | AL096867 | AL592423 | AL035698 | AL096867 | AL096867 | AL592423 | AL035698 | AL096867 | AL035698 | AL592423 | AL035698 | AL096867 | AL592423 | AL035698 | AL096867 | AL592423 | BC136280
InterProIPR001828 | IPR000337 | IPR017978 | IPR017979 | IPR000162 | IPR001256 | IPR017971 | IPR011500 | IPR019588
PRODOM
GENEID2911
MIM604473
PRINTSPR00248 | PR01051 | PR00593
PFAMPF00003 | PF01094 | PF10606 | PF07562
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameMETABOTROPIC GLUTAMATE RECEPTORS_MGLU1_Homo sapiens
DescriptionRecName: Full=Metabotropic glutamate receptor 1; Short=mGluR1;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGRM1 | GPRC1A,MGLUR
FunctionReceptor for glutamate
Fragment0
Sequence
MVGLLLFFFPAIFLEVSLLPRSPGRKVLLAGASSQRSVARMDGDVIIGALFSVHHQPPAE
KVPERKCGEIREQYGIQRVEAMFHTLDKINADPVLLPNITLGSEIRDSCWHSSVALEQSI
EFIRDSLISIRDEKDGINRCLPDGQSLPPGRTKKPIAGVIGPGSSSVAIQVQNLLQLFDI
PQIAYSATSIDLSDKTLYKYFLRVVPSDTLQARAMLDIVKRYNWTYVSAVHTEGNYGESG
MDAFKELAAQEGLCIAHSDKIYSNAGEKSFDRLLRKLRERLPKARVVVCFCEGMTVRGLL
SAMRRLGVVGEFSLIGSDGWADRDEVIEGYEVEANGGITIKLQSPEVRSFDDYFLKLRLD
TNTRNPWFPEFWQHRFQCRLPGHLLENPNFKRICTGNESLEENYVQDSKMGFVINAIYAM
AHGLQNMHHALCPGHVGLCDAMKPIDGSKLLDFLIKSSFIGVSGEEVWFDEKGDAPGRYD
IMNLQYTEANRYDYVHVGTWHEGVLNIDDYKIQMNKSGVVRSVCSEPCLKGQIKVIRKGE
VSCCWICTACKENEYVQDEFTCKACDLGWWPNADLTGCEPIPVRYLEWSNIESIIAIAFS
CLGILVTLFVTLIFVLYRDTPVVKSSSRELCYIILAGIFLGYVCPFTLIAKPTTTSCYLQ
RLLVGLSSAMCYSALVTKTNRIARILAGSKKKICTRKPRFMSAWAQVIIASILISVQLTL
VVTLIIMEPPMPILSYPSIKEVYLICNTSNLGVVAPLGYNGLLIMSCTYYAFKTRNVPAN
FNEAKYIAFTMYTTCIIWLAFVPIYFGSNYKIITTCFAVSLSVTVALGCMFTPKMYIIIA
KPERNVRSAFTTSDVVRMHVGDGKLPCRSNTFLNIFRRKKAGAGNANSNGKSVSWSEPGG
GQVPKGQHMWHRLSVHVKTNETACNQTAVIKPLTKSYQGSGKSLTFSDTSTKTLYNVEEE
EDAQPIRFSPPGSPSMVVHRRVPSAATTPPLPPHLTAEETPLFLAEPALPKGLPPPLQQQ
QQPPPQQKSLMDQLQGVVSNFSTAIPDFHAVLAGPGGPGNGLRSLYPPPPPPQHLQMLPL
QLSTFGEELVSPPADDDDDSERFKLLQEYVYEHEREGNTEEDELEEEEEDLQAASKLTPD
DSPALTPPSPFRDSVASGSSVPSSPVSESVLCTPPNVSYASVILRDYKQSSSTL
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-11_Homo sapiensGq/119076744
2Galpha-14_Homo sapiensGq/119076744
3Galpha-q_Homo sapiensGq/119076744
4Galpha-15_Homo sapiensGq/119076744
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level