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Description Entry page for GPCR - 'FRIZZELED_FZD1_Homo sapiens'
ClassFrizzled/Smoothened
FamilyFRIZZELED
Sub-FamilyFZD1
Cross References:
References
UniProtQ9UP38 | O94815 | Q549T8
EMBLAF072872 | AB017363 | AC084381 | BC051271
InterProIPR000539 | IPR020067 | IPR000024 | IPR020068 | IPR015526 | IPR017981
PRODOM
GENEID8321
MIM603408
PRINTSPR00489
PFAMPF01534 | PF01392
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameFRIZZELED_FZD1_Homo sapiens
DescriptionRecName: Full=Frizzled-1; Short=Fz-1; Short=hFz1; Short=FzE1;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneFZD
FunctionReceptor for Wnt proteins
Fragment0
Sequence
MAEEEAPKKSRAAGGGASWELCAGALSARLAEEGSGDAGGRRRPPVDPRRLARQLLLLLW
LLEAPLLLGVRAQAAGQGPGQGPGPGQQPPPPPQQQQSGQQYNGERGISVPDHGYCQPIS
IPLCTDIAYNQTIMPNLLGHTNQEDAGLEVHQFYPLVKVQCSAELKFFLCSMYAPVCTVL
EQALPPCRSLCERARQGCEALMNKFGFQWPDTLKCEKFPVHGAGELCVGQNTSDKGTPTP
SLLPEFWTSNPQHGGGGHRGGFPGGAGASERGKFSCPRALKVPSYLNYHFLGEKDCGAPC
EPTKVYGLMYFGPEELRFSRTWIGIWSVLCCASTLFTVLTYLVDMRRFSYPERPIIFLSG
CYTAVAVAYIAGFLLEDRVVCNDKFAEDGARTVAQGTKKEGCTILFMMLYFFSMASSIWW
VILSLTWFLAAGMKWGHEAIEANSQYFHLAAWAVPAIKTITILALGQVDGDVLSGVCFVG
LNNVDALRGFVLAPLFVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLEKLMVRIGVF
SVLYTVPATIVIACYFYEQAFRDQWERSWVAQSCKSYAIPCPHLQAGGGAPPHPPMSPDF
TVFMIKYLMTLIVGITSGFWIWSGKTLNSWRKFYTRLTNSKQGETTV
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-11_Homo sapiensGq/1111563835
2Galpha-14_Homo sapiensGq/1111563835
3Galpha-q_Homo sapiensGq/1111563835
4Galpha-15_Homo sapiensGq/1111563835
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level