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Description Entry page for GPCR - 'FRIZZELED_FZD2_Homo sapiens'
ClassFrizzled/Smoothened
FamilyFRIZZELED
Sub-FamilyFZD2
Cross References:
References
UniProtQ14332 | Q0VG82
EMBLL37882 | AB017364 | BC113402 | BC113404
InterProIPR000539 | IPR020067 | IPR000024 | IPR020068 | IPR015526 | IPR017981
PRODOM
GENEID2535
MIM600667
PRINTSPR00489
PFAMPF01534 | PF01392
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameFRIZZELED_FZD2_Homo sapiens
DescriptionRecName: Full=Frizzled-2; Short=Fz-2; Short=hFz2; Short=FzE2;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneFZD
FunctionReceptor for Wnt proteins
Fragment0
Sequence
MRPRSALPRLLLPLLLLPAAGPAQFHGEKGISIPDHGFCQPISIPLCTDIAYNQTIMPNL
LGHTNQEDAGLEVHQFYPLVKVQCSPELRFFLCSMYAPVCTVLEQAIPPCRSICERARQG
CEALMNKFGFQWPERLRCEHFPRHGAEQICVGQNHSEDGAPALLTTAPPPGLQPGAGGTP
GGPGGGGAPPRYATLEHPFHCPRVLKVPSYLSYKFLGERDCAAPCEPARPDGSMFFSQEE
TRFARLWILTWSVLCCASTFFTVTTYLVDMQRFRYPERPIIFLSGCYTMVSVAYIAGFVL
QERVVCNERFSEDGYRTVVQGTKKEGCTILFMMLYFFSMASSIWWVILSLTWFLAAGMKW
GHEAIEANSQYFHLAAWAVPAVKTITILAMGQIDGDLLSGVCFVGLNSLDPLRGFVLAPL
FVYLFIGTSFLLAGFVSLFRIRTIMKHDGTKTEKLERLMVRIGVFSVLYTVPATIVIACY
FYEQAFREHWERSWVSQHCKSLAIPCPAHYTPRMSPDFTVYMIKYLMTLIVGITSGFWIW
SGKTLHSWRKFYTRLTNSRHGETTV
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-11_Homo sapiensGq/1111563835
2Galpha-14_Homo sapiensGq/1111563835
3Galpha-q_Homo sapiensGq/1111563835
4Galpha-t3_Homo sapiensGt11563835
5Galpha-15_Homo sapiensGq/1111563835
6Galpha-t1_Homo sapiensGt11563835
7Galpha-t2_Homo sapiensGt11563835
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level