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Description Entry page for GPCR - 'OREXIN RECEPTORS_OX2_Homo sapiens'
ClassCLASS A
FamilyOREXIN RECEPTORS
Sub-FamilyOX2
Cross References:
References
UniProtO43614 | Q5VTM0
EMBLAF041245 | AY062031 | AL591718 | AL449104 | AL449104 | AL591718 | CH471081
InterProIPR000276 | IPR017452 | IPR000204 | IPR004060
PRODOM
GENEID3062
MIM602393
PRINTSPR00237 | PR01522 | PR01064
PFAMPF00001 | PF03827
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameOREXIN RECEPTORS_OX2_Homo sapiens
DescriptionRecName: Full=Orexin receptor type 2;AltName: Full=Ox2r;AltName: Full=Hypocretin receptor type 2
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneHCRTR
FunctionNonselective, high-affinity receptor for both orexin-As and orexin-B neuropeptides
Fragment0
Sequence
MSGTKLEDSPPCRNWSSASELNETQEPFLNPTDYDDEEFLRYLWREYLHPKEYEWVLIAG
YIIVFVVALIGNVLVCVAVWKNHHMRTVTNYFIVNLSLADVLVTITCLPATLVVDITETW
FFGQSLCKVIPYLQTVSVSVSVLTLSCIALDRWYAICHPLMFKSTAKRARNSIVIIWIVS
CIIMIPQAIVMECSTVFPGLANKTTLFTVCDERWGGEIYPKMYHICFFLVTYMAPLCLMV
LAYLQIFRKLWCRQIPGTSSVVQRKWKPLQPVSQPRGPGQPTKSRMSAVAAEIKQIRARR
KTARMLMIVLLVFAICYLPISILNVLKRVFGMFAHTEDRETVYAWFTFSHWLVYANSAAN
PIIYNFLSGKFREEFKAAFSCCCLGVHHRQEDRLTRGRTSTESRKSLTTQISNFDNISKL
SEQVVLTSISTLPAANGAGPLQNW
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-11_Homo sapiensGq/119491897
2Galpha-14_Homo sapiensGq/119491897
3Galpha-q_Homo sapiensGq/119491897
4Galpha-15_Homo sapiensGq/119491897
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level