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Description Entry page for GPCR - 'FRIZZELED_FZD8_Homo sapiens'
ClassFrizzled/Smoothened
FamilyFRIZZELED
Sub-FamilyFZD8
Cross References:
References
UniProtQ9H461
EMBLAB043703 | AL121749
InterProIPR000539 | IPR020067 | IPR000024 | IPR020068 | IPR015526 | IPR017981
PRODOM
GENEID8325
MIM606146
PRINTSPR00489
PFAMPF01534 | PF01392
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameFRIZZELED_FZD8_Homo sapiens
DescriptionRecName: Full=Frizzled-8; Short=Fz-8; Short=hFz8;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneFZD
FunctionReceptor for Wnt proteins
Fragment0
Sequence
MEWGYLLEVTSLLAALALLQRSSGAAAASAKELACQEITVPLCKGIGYNYTYMPNQFNHD
TQDEAGLEVHQFWPLVEIQCSPDLKFFLCSMYTPICLEDYKKPLPPCRSVCERAKAGCAP
LMRQYGFAWPDRMRCDRLPEQGNPDTLCMDYNRTDLTTAAPSPPRRLPPPPPGEQPPSGS
GHGRPPGARPPHRGGGRGGGGGDAAAPPARGGGGGGKARPPGGGAAPCEPGCQCRAPMVS
VSSERHPLYNRVKTGQIANCALPCHNPFFSQDERAFTVFWIGLWSVLCFVSTFATVSTFL
IDMERFKYPERPIIFLSACYLFVSVGYLVRLVAGHEKVACSGGAPGAGGAGGAGGAAAGA
GAAGAGAGGPGGRGEYEELGAVEQHVRYETTGPALCTVVFLLVYFFGMASSIWWVILSLT
WFLAAGMKWGNEAIAGYSQYFHLAAWLVPSVKSIAVLALSSVDGDPVAGICYVGNQSLDN
LRGFVLAPLVIYLFIGTMFLLAGFVSLFRIRSVIKQQDGPTKTHKLEKLMIRLGLFTVLY
TVPAAVVVACLFYEQHNRPRWEATHNCPCLRDLQPDQARRPDYAVFMLKYFMCLVVGITS
GVWVWSGKTLESWRSLCTRCCWASKGAAVGGGAGATAAGGGGGPGGGGGGGPGGGGGPGG
GGGSLYSDVSTGLTWRSGTASSVSYPKQMPLSQV
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level