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Summary sheet information for Effector 'RGS PX1-Homo sapiens'
Name RGS PX1-Homo sapiens
Description RecName: Full=Sorting nexin-13;AltName: Full=RGS domain- and PHOX domain-containing protein;AltName: Full=RGS-PX1
Class
Family Regulators of G-protein signaling
Sub_family Regulators of G-protein signaling
type RGS PX1
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 7
Gene Start: 17798181
Gene End: 17903721
Ensembl Contig View
Ensembl Genes:
ENSG00000071189
EMBL:
EMBL ID  Description
AB018256  Homo sapiens mRNA for KIAA0713 protein, partial cds.
AF121862  Homo sapiens sorting nexin 13 (SNX13) mRNA, partial cds.
AF420470  Homo sapiens RGS-PX1 mRNA, complete cds.
AK315135  Homo sapiens cDNA, FLJ96101, Homo sapiens sorting nexin 13 (SNX13), mRNA.
AL353943  Homo sapiens mRNA; cDNA DKFZp761E0611 (from clone DKFZp761E0611)
BC022060  Homo sapiens, Similar to sorting nexin 13, clone IMAGE:4719518, mRNA, partial cds.
BC045667  Homo sapiens sorting nexin 13, mRNA (cDNA clone MGC:44494 IMAGE:5298570), complete cds.
CH471073  Homo sapiens 211000035839577 genomic scaffold, whole genome shotgun sequence.

EntrezGene:
ID  Description
SNX13  sorting nexin 13
RefSeq DNA:
ID  Description
NM_015132  Homo sapiens sorting nexin 13 (SNX13), mRNA.

UniGene:
ID  Description
Proteins
Ensembl Proteins:
ENSP00000316762; ENSP00000242044
Entrez Proteins:
AAD27835.1; AAH22060.1; AAH45667.1; AAL37728.1; BAA34433.1; BAG37586.1; CAB89251.2; EAW93690.1; EAW93692.1
RefSeq Proteins:
ID  Description
NP_055947  sorting nexin 13 [Homo sapiens].

UniProt:
ID  Description
Q9Y5W8-2  UNKNOWN
B2RCI9  SubName: Full=cDNA, FLJ96101, Homo sapiens sorting nexin 13 (SNX13), mRNA (Sorting nexin 13, isoform CRA_b);
Q86XC4  SubName: Full=Sorting nexin 13;
Q9NSH0  SubName: Full=Putative uncharacterized protein DKFZp761E0611; SubName: Full=Sorting nexin 13, isoform CRA_d;
Q9Y5W8  RecName: Full=Sorting nexin-13; AltName: Full=RGS domain- and PHOX domain-containing protein; AltName: Full=RGS-PX1;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL
     RGS PX1-Homo sapiens    

InterPro:
ID  Name
IPR000342  Regulat_G_prot_signal
IPR001683  PX
IPR003114  PX_assoc
IPR013996  PX_assoc_Snx13
IPR013937  Sorting_nexin_C
Pfam:
ID  Description
RGS  Regulator of G protein signaling domain
PX  PX domain
PXA  PXA domain
Nexin_C  Sorting nexin C terminal

Structure
PDB:
ID
HSSP:
ID  Description
PSSH:
ID  Description
Q86XC4  UNKNOWN
Q9Y5W8  UNKNOWN
Diseases
OMIM:
OMIM ID  Name  Alt Name
606589  SORTING NEXIN 13   SNX13 RGS DOMAIN- AND PHOX DOMAIN-CONTAINING PROTEIN; RGS-PX1 KIAA0713
Gene Ontology
GO:
GO ID  Description
GO:0004129  cytochrome-c oxidase activity
GO:0004871  signal transducer activity
GO:0005515  protein binding
GO:0007154  cell communication
GO:0009968  negative regulation of signal transduction
GO:0015031  protein transport
GO:0035091  phosphoinositide binding
Pathway
KEGG:
KEGG PATHWAY ID  Name
Panther:
ID  Description
P00026  Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000071189 Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8] Pan_troglodytesone2one ENSPTRG00000018957Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]SNX13
Pongo_pygmaeusone2one ENSPPYG00000017757Putative uncharacterized protein DKFZp469H181. [Source:UniProtKB/TrEMBL;Acc:Q5RFU3][hgnc]
Macaca_mulattaone2one ENSMMUG00000021915Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000001715Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Microcebus_murinusone2one ENSMICG00000014067Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Otolemur_garnettiione2one ENSOGAG00000001781Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Equus_caballusone2one ENSECAG00000021498Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]LOC100066218
Tursiops_truncatusone2one ENSTTRG00000003083Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Loxodonta_africanaone2one ENSLAFG00000010912Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Spermophilus_tridecemlineatusone2one ENSSTOG00000001983Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Vicugna_pacosone2one ENSVPAG00000008444Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000004268Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Canis_familiarisone2one ENSCAFG00000002467Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]SNX13
Tupaia_belangerione2one ENSTBEG00000003638Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000016319Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Bos_taurusone2one ENSBTAG00000014074Similar to Sorting nexin-13 (RGS domain-and PHOX domain-containing protein) (RGS-PX1). [Source:UniProtKB/TrEMBL;Acc:A0JN89][hgnc]SNX13
Oryctolagus_cuniculusone2one ENSOCUG00000001142Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Cavia_porcellusone2one ENSCPOG00000009570Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Myotis_lucifugusone2one ENSMLUG00000014405Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Sorex_araneusone2one ENSSARG00000005704Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Echinops_telfairione2one ENSETEG00000016728Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Procavia_capensisone2one ENSPCAG00000011268Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Dipodomys_ordiione2one ENSDORG00000005766Sorting nexin-13 [Source:UniProtKB/Swiss-Prot;Acc:Q6PHS6][hgnc]
Mus_musculusone2one ENSMUSG00000020590Sorting nexin-13 [Source:UniProtKB/Swiss-Prot;Acc:Q6PHS6][hgnc]Snx13
Rattus_norvegicusone2one ENSRNOG00000004186Sorting nexin-13 [Source:UniProtKB/Swiss-Prot;Acc:Q6PHS6][hgnc]
Erinaceus_europaeusone2one ENSEEUG00000013530Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Ochotona_princepsone2one ENSOPRG00000016205Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000009612Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]100084063
Gallus_gallusone2one ENSGALG00000010840Hypothetical protein. [Source:UniProtKB/TrEMBL;Acc:Q5ZMQ6][hgnc]RCJMB04_1g21
Monodelphis_domesticaone2one ENSMODG00000001464Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Xenopus_tropicalisone2one ENSXETG00000022783Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Danio_rerioone2one ENSDARG00000013828hypothetical protein LOC503733 [Source:RefSeq_peptide;Acc:NP_001013329][hgnc]LOC100007329
Oryzias_latipesone2one ENSORLG00000004022Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Gasterosteus_aculeatusone2one ENSGACG00000006404Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]
Takifugu_rubripesone2one ENSTRUG00000014752Sorting nexin 13. [Source:UniProtKB/TrEMBL;Acc:Q8AX93][hgnc]
Tetraodon_nigroviridisone2one ENSTNIG00000017776Sorting nexin-13 (RGS domain- and PHOX domain-containing protein) (RGS-PX1) [Source:UniProtKB/Swiss-Prot;Acc:Q9Y5W8][hgnc]