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Summary sheet information for GPCR 'VIP AND PACAP RECEPTORS_VPAC2_Homo sapiens'
Name VIP AND PACAP RECEPTORS_VPAC2_Homo sapiens
Description RecName: Full=Vasoactive intestinal polypeptide receptor 2; Short=VIP-R-2;AltName: Full=Pituitary adenylate cyclase-activating polypeptide type III receptor; Short=PACAP type III receptor;AltName: Full=PACAP-R-3;AltName: Full=Helodermin-preferring VIP receptor;Flags: Precursor
Class CLASS B
Family VIP AND PACAP RECEPTORS
Sub_family VPAC2
type
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 7
Gene Start: 158513628
Gene End: 158630410
Ensembl Contig View
Ensembl Genes:
ENSG00000106018
EMBL:
EMBL ID  Description
AF027390  Homo sapiens 7q telomere, complete sequence.
AK131406  Homo sapiens cDNA FLJ16511 fis, clone HEART2009680, highly similar to Vasoactive intestinal polypeptide receptor 2 precursor.
BC010569  Homo sapiens vasoactive intestinal peptide receptor 2, mRNA (cDNA clone MGC:17082 IMAGE:4178593), complete cds.
BT007118  Homo sapiens vasoactive intestinal peptide receptor 2 mRNA, complete cds.
CH236954  Homo sapiens chromosome 7 Scaffold09, whole genome shotgun sequence.
CH471149  Homo sapiens 211000035843051 genomic scaffold, whole genome shotgun sequence.
L36566  Human helodermin-preferring VIP receptor (VIP2/PACAP receptor) mRNA, complete cds.
L40764  Homo sapiens vasoactive intestinal polypeptide receptor 2 (VIPR2) mRNA, complete cds.
U18810  Human PACAP type-3/VIP type-2 receptor mRNA, complete cds.
X95097  Homo sapiens mRNA for VIP receptor 2
Y18423  Homo sapiens VIP2R gene, exons 1-2 (and joined CDS)
Y18424  Homo sapiens VIPR2 gene exon 3
Y18425  Homo sapiens VIPR2 gene exon 4
Y18426  Homo sapiens VIPR2 gene exon 5
Y18427  Homo sapiens VIP2R gene, exon 6
Y18428  Homo sapiens VIP2R gene, exon 7
Y18429  Homo sapiens VIP2R gene, exon 8
Y18430  Homo sapiens VIP2R gene, exons 9-12
Y18431  Homo sapiens VIP2R gene, exon 13

EntrezGene:
ID  Description
VIPR2  vasoactive intestinal peptide receptor 2
RefSeq DNA:
ID  Description
NM_003382  Homo sapiens vasoactive intestinal peptide receptor 2 (VIPR2), mRNA.

UniGene:
ID  Description
Hs.654505  Vasoactive intestinal peptide receptor 2, mRNA (cDNA clone MGC:17082 IMAGE:4178593)

Proteins
Ensembl Proteins:
ENSP00000262178; ENSP00000384497; ENSP00000366860
Entrez Proteins:
AAC09171.1; AAC37569.1; AAC41756.1; AAC50872.1; AAH10569.1; AAP35782.1; BAD18553.1; CAA64474.1; CAB41899.1; EAL23936.1; EAX04596.1
RefSeq Proteins:
ID  Description
NP_003373  vasoactive intestinal peptide receptor 2 [Homo sapiens].

UniProt:
ID  Description
Q53Y09  SubName: Full=Vasoactive intestinal peptide receptor 2;
Q6ZN22  SubName: Full=cDNA FLJ16511 fis, clone HEART2009680, highly similar to Vasoactive intestinal polypeptide receptor 2;
Q71V81  SubName: Full=Vasoactive intestinal polypeptide receptor 2; Flags: Fragment;
Q9UCW0  SubName: Full=Type II vasoactive intestinal peptide receptor, type II VIPR, HVR2; Flags: Fragment;
P41587  RecName: Full=Vasoactive intestinal polypeptide receptor 2; Short=VIP-R-2; AltName: Full=Pituitary adenylate cyclase-activating polypeptide type III receptor; Short=PACAP type III receptor; AltName: Full=PACAP-R-3; AltName: Full=Helodermin-preferring VIP receptor; Flags: Precursor;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR017981  GPCR_2-like
IPR001571  GPCR_2_VIP_rcpt
IPR000832  GPCR_2_secretin-like
IPR017983  GPCR_2_secretin-like_CS
IPR002284  GPCR_2_VIP_rcpt_2
IPR001879  GPCR_2_extracellular
Pfam:
ID  Description
7tm_2  7 transmembrane receptor (Secretin family)
HRM  Hormone receptor domain

Structure
PDB:
ID
HSSP:
ID  Description
2jod  SIGNALING PROTEIN
PSSH:
ID  Description
Q53Y09  UNKNOWN
P41587  UNKNOWN
Diseases
OMIM:
OMIM ID  Name  Alt Name
601970  VASOACTIVE INTESTINAL PEPTIDE RECEPTOR 2; VIPR2   UNKNOWN
Gene Ontology
GO:
GO ID  Description
GO:0004872  receptor activity
GO:0004930  G-protein coupled receptor activity
GO:0004999  vasoactive intestinal polypeptide receptor activity
GO:0005886  plasma membrane
GO:0005887  integral to plasma membrane
GO:0007165  signal transduction
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007267  cell-cell signaling
GO:0016020  membrane
Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04080  Neuroactive ligand-receptor interaction

Panther:
ID  Description
Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Other GPCR resources
Links to other GPCR resources
GPCRDB | GPCR-OKB | GLIDA
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000106018 Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587] Bos_taurusone2one ENSBTAG00000018648Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]LOC789535
Mus_musculusone2one ENSMUSG00000011171Vasoactive intestinal polypeptide receptor 2 Precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41588][hgnc]Vipr2
Felis_catusone2one ENSFCAG00000009039Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Otolemur_garnettiione2one ENSOGAG00000008327Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Loxodonta_africanaone2one ENSLAFG00000003360Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Cavia_porcellusone2one ENSCPOG00000006143Gastric VPAC2 receptor. [Source:UniProtKB/TrEMBL;Acc:Q6PRD2][hgnc]
Tursiops_truncatusone2one ENSTTRG00000004845Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Macaca_mulattaone2one ENSMMUG00000009611Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Pongo_pygmaeusone2one ENSPPYG00000018236Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Pan_troglodytesone2one ENSPTRG00000019929Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000005866Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Oryctolagus_cuniculusone2one ENSOCUG00000003473Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Ochotona_princepsone2one ENSOPRG00000003027Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Spermophilus_tridecemlineatusone2one ENSSTOG00000006168Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Equus_caballusone2one ENSECAG00000007939Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]LOC100057396
Rattus_norvegicusone2one ENSRNOG00000004317Vasoactive intestinal polypeptide receptor 2 precursor (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3). [Source:UniProtKB/Swiss-Prot;Acc:P35000][hgnc]Vipr2
Canis_familiarisone2one ENSCAFG00000005255Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]VIPR2
Dasypus_novemcinctusone2one ENSDNOG00000004253Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000014138Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Echinops_telfairione2one ENSETEG00000007218Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Tupaia_belangeriapprent_one2one ENSTBEG00000012340Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Procavia_capensisone2one ENSPCAG00000001813Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000006114Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]100080907
Monodelphis_domesticaone2one ENSMODG00000005472Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Gallus_gallusone2one ENSGALG00000006575vasoactive intestinal peptide receptor 2 [Source:RefSeq_peptide;Acc:NP_001014970][hgnc]VIPR2
Gasterosteus_aculeatusone2many ENSGACG00000017549Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Danio_rerioone2many ENSDARG00000067568Pituitary adenylate cyclase-activating peptide (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q98TU4][hgnc]
Oryzias_latipesone2many ENSORLG00000005878Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Danio_rerioone2many ENSDARG00000012353Pituitary adenylate cyclase-activating peptide (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q98TU4][hgnc]vipr2
Tetraodon_nigroviridisone2many ENSTNIG00000007985Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Takifugu_rubripesone2many ENSTRUG00000005848Vasoactive intestinal peptide receptor (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q802T6][hgnc]
Takifugu_rubripesone2many ENSTRUG00000017701Vasoactive intestinal peptide receptor (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q802T7][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000008704Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000001845Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Oryzias_latipesone2many ENSORLG00000019029Vasoactive intestinal polypeptide receptor 2 (VIP-R-2) (Pituitary adenylate cyclase-activating polypeptide type III receptor) (PACAP type III receptor) (PACAP-R-3) [Source:UniProtKB/Swiss-Prot;Acc:P41587][hgnc]
Aedes_aegyptione2many AAEL010043calcitonin receptor[hgnc]