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Summary sheet information for GPCR 'SOMATOSTATIN RECEPTORS_SST1_Homo sapiens'
Name SOMATOSTATIN RECEPTORS_SST1_Homo sapiens
Description RecName: Full=Somatostatin receptor type 1;AltName: Full=SS1R;AltName: Full=SRIF-2
Class CLASS A
Family SOMATOSTATIN RECEPTORS
Sub_family SST1
type
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 14
Gene Start: 37746955
Gene End: 37752019
Ensembl Contig View
Ensembl Genes:
ENSG00000139874
EMBL:
EMBL ID  Description
AY322536  Homo sapiens somatostatin receptor 1 gene, complete cds.
BC035618  Homo sapiens somatostatin receptor 1, mRNA (cDNA clone MGC:45280 IMAGE:5175220), complete cds.
M81829  Human somatostatin receptor isoform 1 gene, complete cds.

EntrezGene:
ID  Description
SSTR1  somatostatin receptor 1
RefSeq DNA:
ID  Description
NM_001049  Homo sapiens somatostatin receptor 1 (SSTR1), mRNA.

UniGene:
ID  Description
Hs.248160  Somatostatin receptor 1, mRNA (cDNA clone MGC:45280 IMAGE:5175220)

Proteins
Ensembl Proteins:
ENSP00000379570; ENSP00000267377
Entrez Proteins:
AAA58247.1; AAH35618.1; AAP84349.1
RefSeq Proteins:
ID  Description
NP_001040  somatostatin receptor 1 [Homo sapiens].

UniProt:
ID  Description
P30872  RecName: Full=Somatostatin receptor type 1; AltName: Full=SS1R; AltName: Full=SRIF-2;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR000276  GPCR_Rhodpsn
IPR001116  Somatstn_rcpt_1
IPR000586  Somatstn_rcpt
IPR017452  GPCR_Rhodpsn_supfam
Pfam:
ID  Description
7tm_1  7 transmembrane receptor (rhodopsin family)

Structure
PDB:
ID
HSSP:
ID  Description
PSSH:
ID  Description
P30872  UNKNOWN
Diseases
OMIM:
OMIM ID  Name  Alt Name
182451  SOMATOSTATIN RECEPTOR 1; SSTR1   UNKNOWN
Gene Ontology
GO:
GO ID  Description
GO:0001584  rhodopsin-like receptor activity
GO:0004872  receptor activity
GO:0004983  neuropeptide Y receptor activity
GO:0004985  opioid receptor activity
GO:0004994  somatostatin receptor activity
GO:0005624  membrane fraction
GO:0005886  plasma membrane
GO:0005887  integral to plasma membrane
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007187  G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0007215  glutamate signaling pathway
GO:0007218  neuropeptide signaling pathway
GO:0007267  cell-cell signaling
GO:0007584  response to nutrient
GO:0007586  digestion
GO:0008285  negative regulation of cell proliferation
GO:0016021  integral to membrane
GO:0030273  melanin-concentrating hormone receptor activity
GO:0045028  purinergic nucleotide receptor activity, G-protein coupled
Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04080  Neuroactive ligand-receptor interaction

Panther:
ID  Description
P00026  Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00027  Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Chemicals
DrugBank:
ID  Name  Synonyms
DB00104  Octreotide  Octreotida [Spanish]; Octreotide acetate; Octreotidum [Latin]; Octrotide
HMDB:
ID  Name  Synonyms
Other GPCR resources
Links to other GPCR resources
GPCRDB | GPCR-OKB | GLIDA
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000139874 Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872] Pan_troglodytesone2one ENSPTRG00000006289Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]SSTR1
Pongo_pygmaeusone2one ENSPPYG00000005761Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Macaca_mulattaone2one ENSMMUG00000018563Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Microcebus_murinusone2one ENSMICG00000008935Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Tupaia_belangerione2one ENSTBEG00000013119Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Dasypus_novemcinctusone2one ENSDNOG00000000662Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Equus_caballusone2one ENSECAG00000004716Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]LOC100060276
Bos_taurusone2one ENSBTAG00000006582Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]SSTR1
Cavia_porcellusone2one ENSCPOG00000003720Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Tursiops_truncatusone2one ENSTTRG00000003528Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Dipodomys_ordiione2one ENSDORG00000015028Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30873][hgnc]
Canis_familiarisone2one ENSCAFG00000013755Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Felis_catusone2one ENSFCAG00000009489Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Erinaceus_europaeusone2one ENSEEUG00000002520Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Rattus_norvegicusone2one ENSRNOG00000022714Somatostatin receptor type 1 (SS1R) (SRIF-2). [Source:UniProtKB/Swiss-Prot;Acc:P28646][hgnc]Sstr1
Mus_musculusone2one ENSMUSG00000035431Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30873][hgnc]Sstr1
Gallus_gallusone2one ENSGALG00000010139Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]SSTR1
Monodelphis_domesticaone2one ENSMODG00000012009Somatostatin receptor type 1 (SS1R) (SRIF-2) [Source:UniProtKB/Swiss-Prot;Acc:P30872][hgnc]
Danio_rerioone2one ENSDARG00000003049[hgnc]LOC568254
Anopheles_gambiaemany2many AGAP012268putative somatostatin receptor [Source:Anopheles_symbol;Acc:GPRSMS][hgnc]GPRSMS
Anopheles_gambiaemany2many AGAP010486putative allatostatin receptor 3 [Source:Anopheles_symbol;Acc:GPRALS3][hgnc]GPRALS3