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Summary sheet information for GPCR 'SOMATOSTATIN RECEPTORS_SST5_Homo sapiens'
Name SOMATOSTATIN RECEPTORS_SST5_Homo sapiens
Description RecName: Full=Somatostatin receptor type 5;AltName: Full=SS5R
Class CLASS A
Family SOMATOSTATIN RECEPTORS
Sub_family SST5
type
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes
Gene Location:
Chromosome: 16
Gene Start: 1062757
Gene End: 1071438
Ensembl Contig View
Ensembl Genes:
ENSG00000162009
EMBL:
EMBL ID  Description
AE006466  Homo sapiens 16p13.3 sequence section 5 of 8.
AL031713  Human DNA sequence from clone LA16c-349E11 on chromosome 16 Contains the SSTR5 gene for somatostatin receptor 5, a GSS and five putative CpG islands.
AY081193  Homo sapiens somatostatin receptor subtype 5 gene, exons 1a and 1 and complete cds.
CH471112  Homo sapiens 211000035837318 genomic scaffold, whole genome shotgun sequence.
D16827  Homo sapiens gene for fifth somatostatin receptor subtype, complete cds.
L14865  Human somatostatin receptor (SST) gene, complete cds.

EntrezGene:
ID  Description
SSTR5  somatostatin receptor 5
RefSeq DNA:
ID  Description
NM_001053  Homo sapiens somatostatin receptor 5 (SSTR5), mRNA.

UniGene:
ID  Description
Hs.449840  Somatostatin receptor 5 (SSTR5), mRNA

Proteins
Ensembl Proteins:
ENSP00000380680; ENSP00000293897
Entrez Proteins:
AAA20828.1; AAK61266.1; AAL88744.1; BAA04107.1; EAW85687.1
RefSeq Proteins:
ID  Description
NP_001044  somatostatin receptor 5 [Homo sapiens].

UniProt:
ID  Description
Q541E0  SubName: Full=Somatostatin receptor subtype 5 (Somatostatin receptor 5);
P35346  RecName: Full=Somatostatin receptor type 5; AltName: Full=SS5R;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR000276  GPCR_Rhodpsn
IPR001184  Somatstn_rcpt_5
IPR000586  Somatstn_rcpt
IPR017452  GPCR_Rhodpsn_supfam
Pfam:
ID  Description
7tm_1  7 transmembrane receptor (rhodopsin family)

Structure
PDB:
ID
HSSP:
ID  Description
2vt4  RECEPTOR
PSSH:
ID  Description
Q541E0  UNKNOWN
P35346  UNKNOWN
Diseases
OMIM:
OMIM ID  Name  Alt Name
182455  SOMATOSTATIN RECEPTOR 5; SSTR5   UNKNOWN
Gene Ontology
GO:
GO ID  Description
GO:0001584  rhodopsin-like receptor activity
GO:0004872  receptor activity
GO:0004983  neuropeptide Y receptor activity
GO:0004985  opioid receptor activity
GO:0004994  somatostatin receptor activity
GO:0005886  plasma membrane
GO:0005887  integral to plasma membrane
GO:0007165  signal transduction
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007187  G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0008285  negative regulation of cell proliferation
GO:0016021  integral to membrane
GO:0016494  C-X-C chemokine receptor activity
GO:0042593  glucose homeostasis
GO:0045028  purinergic nucleotide receptor activity, G-protein coupled
GO:0050796  regulation of insulin secretion
Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04080  Neuroactive ligand-receptor interaction

Panther:
ID  Description
P00026  Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00027  Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Chemicals
DrugBank:
ID  Name  Synonyms
DB00104  Octreotide  Octreotida [Spanish]; Octreotide acetate; Octreotidum [Latin]; Octrotide
HMDB:
ID  Name  Synonyms
Other GPCR resources
Links to other GPCR resources
GPCRDB | GPCR-OKB | GLIDA
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000162009 Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346] Pan_troglodytesone2one ENSPTRG00000007576Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]SSTR5
Pongo_pygmaeusone2one ENSPPYG00000006939Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Canis_familiarisone2one ENSCAFG00000019600Somatostatin receptor 5 (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q7YS15][hgnc]SSTR5
Felis_catusone2one ENSFCAG00000004225Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Dipodomys_ordiione2one ENSDORG00000002614Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:O08858][hgnc]
Equus_caballusone2one ENSECAG00000005022Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]LOC100067398
Myotis_lucifugusone2one ENSMLUG00000013219Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Tursiops_truncatusone2one ENSTTRG00000005905Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Bos_taurusone2one ENSBTAG00000039974Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]SSTR5
Pteropus_vampyrusone2one ENSPVAG00000013511Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Procavia_capensisone2one ENSPCAG00000014940Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Ochotona_princepsone2one ENSOPRG00000017290Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Cavia_porcellusone2one ENSCPOG00000022586Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Mus_musculusone2one ENSMUSG00000050824Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:O08858][hgnc]Sstr5
Rattus_norvegicusone2one ENSRNOG00000018834Somatostatin receptor type 5 (SS5R). [Source:UniProtKB/Swiss-Prot;Acc:P30938][hgnc]Sstr5
Otolemur_garnettiione2one ENSOGAG00000010913Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Ornithorhynchus_anatinusone2one ENSOANG00000009657Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]100092301
Monodelphis_domesticaone2one ENSMODG00000016906Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Gallus_gallusone2one ENSGALG00000005258somatostatin receptor 5 [Source:RefSeq_peptide;Acc:NP_001020005][hgnc]SSTR5
Xenopus_tropicalisone2one ENSXETG00000005731Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000018944Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Takifugu_rubripesone2one ENSTRUG00000007938Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Tetraodon_nigroviridisone2one ENSTNIG00000014076Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Gasterosteus_aculeatusone2many ENSGACG00000012535Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Danio_rerioone2one ENSDARG00000042081hypothetical protein LOC406588 [Source:RefSeq_peptide;Acc:NP_998462][hgnc]zgc:85682
Oryzias_latipesone2one ENSORLG00000010452Somatostatin receptor type 5 (SS5R) [Source:UniProtKB/Swiss-Prot;Acc:P35346][hgnc]
Anopheles_gambiaemany2many AGAP012268putative somatostatin receptor [Source:Anopheles_symbol;Acc:GPRSMS][hgnc]GPRSMS
Anopheles_gambiaemany2many AGAP010486putative allatostatin receptor 3 [Source:Anopheles_symbol;Acc:GPRALS3][hgnc]GPRALS3