homebrowseblast searchadvanced searchhelp
Quick search:







Summary sheet information for GPCR 'SOMATOSTATIN RECEPTORS_SST3_Homo sapiens'
Name SOMATOSTATIN RECEPTORS_SST3_Homo sapiens
Description RecName: Full=Somatostatin receptor type 3;AltName: Full=SS3R;AltName: Full=SSR-28
Class CLASS A
Family SOMATOSTATIN RECEPTORS
Sub_family SST3
type
Protein features link Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level
Expand All Collapse All
Genes
Gene Location:
Chromosome: 22
Gene Start: 35932098
Gene End: 35938362
Ensembl Contig View
Ensembl Genes:
ENSG00000183473
EMBL:
EMBL ID  Description
AK291165  Homo sapiens cDNA FLJ77124 complete cds, highly similar to Homo sapiens somatostatin receptor 3 (SSTR3), mRNA.
AY277678  Homo sapiens somatostatin receptor subtype 3 gene, promoter region and complete cds.
AY322541  Homo sapiens somatostatin receptor 3 gene, complete cds.
BC042068  Homo sapiens, Similar to somatostatin receptor 3, clone IMAGE:5730411, mRNA, partial cds.
BC096829  Homo sapiens somatostatin receptor 3, mRNA (cDNA clone MGC:111697 IMAGE:6971896), complete cds.
CR456585  Homo sapiens SSTR3 full length open reading frame (ORF) cDNA clone (cDNA clone C22ORF:pGEM.SSTR3.V2)
M96738  Human somatostatin receptor subtype 3 (SSTR3) gene, complete cds.
Z82188  Human DNA sequence from clone RP1-151B14 on chromosome 22 Contains, the 5' end of the IL2RB gene for interleukin 2 receptor, beta, a novel gene, the C1QTNF6 gene for C1q and tumor necrosis factor related protein 6, the SSTR3 gene for somatostatin receptor 3, the RAC2 gene for ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2), a ribosomal protein L39 (RPL39) pseudogene and three CpG islands.

EntrezGene:
ID  Description
SSTR3  somatostatin receptor 3
RefSeq DNA:
ID  Description
NM_001051  Homo sapiens somatostatin receptor 3 (SSTR3), mRNA.

UniGene:
ID  Description
Hs.225995  CDNA FLJ77124 complete cds, highly similar to Homo sapiens somatostatin receptor 3 (SSTR3), mRNA

Proteins
Ensembl Proteins:
ENSP00000384904; ENSP00000330138
Entrez Proteins:
AAA60592.1; AAH42068.1; AAH96829.1; AAP32288.1; AAP84354.1; BAF83854.1; CAB45263.1; CAG30471.1
RefSeq Proteins:
ID  Description
NP_001042  somatostatin receptor 3 [Homo sapiens].

UniProt:
ID  Description
A8K550  UNKNOWN
Q86YF2  SubName: Full=Similar to somatostatin receptor 3; Flags: Fragment;
P32745  RecName: Full=Somatostatin receptor type 3; AltName: Full=SS3R; AltName: Full=SSR-28;

Domains
SMART:
- Hyperlink to SMART; - Hyperlink to ENSEMBL

InterPro:
ID  Name
IPR000276  GPCR_Rhodpsn
IPR000586  Somatstn_rcpt
IPR017452  GPCR_Rhodpsn_supfam
IPR001856  Somatstn_rcpt_3
Pfam:
ID  Description
7tm_1  7 transmembrane receptor (rhodopsin family)

Structure
PDB:
ID
HSSP:
ID  Description
PSSH:
ID  Description
Q86YF2  UNKNOWN
P32745  UNKNOWN
Diseases
OMIM:
OMIM ID  Name  Alt Name
182453  SOMATOSTATIN RECEPTOR 3; SSTR3   UNKNOWN
Gene Ontology
GO:
GO ID  Description
GO:0001584  rhodopsin-like receptor activity
GO:0004872  receptor activity
GO:0004983  neuropeptide Y receptor activity
GO:0004985  opioid receptor activity
GO:0004994  somatostatin receptor activity
GO:0005886  plasma membrane
GO:0005887  integral to plasma membrane
GO:0007165  signal transduction
GO:0007186  G-protein coupled receptor protein signaling pathway
GO:0007187  G-protein signaling, coupled to cyclic nucleotide second messenger
GO:0007267  cell-cell signaling
GO:0008285  negative regulation of cell proliferation
GO:0008628  induction of apoptosis by hormones
GO:0016021  integral to membrane
GO:0016494  C-X-C chemokine receptor activity
GO:0031513  nonmotile primary cilium
GO:0045028  purinergic nucleotide receptor activity, G-protein coupled
Pathway
KEGG:
KEGG PATHWAY ID  Name
hsa04080  Neuroactive ligand-receptor interaction

Panther:
ID  Description
P00026  Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
P00027  Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Chemicals
DrugBank:
ID  Name  Synonyms
HMDB:
ID  Name  Synonyms
Other GPCR resources
Links to other GPCR resources
GPCRDB | GPCR-OKB | GLIDA
Orthology
Orthology Relations:
Gene Gene Description Organism Orthology type Orthologs Orthologs Description
ENSG00000183473 Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745] Pongo_pygmaeusone2one ENSPPYG00000011790Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Macaca_mulattaone2one ENSMMUG00000018853Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Felis_catusone2one ENSFCAG00000013748Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Microcebus_murinusone2one ENSMICG00000017774Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Tarsius_syrichtaone2one ENSTSYG00000009523Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Equus_caballusone2one ENSECAG00000006895Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]LOC100069706
Echinops_telfairione2one ENSETEG00000006312Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Erinaceus_europaeusone2one ENSEEUG00000014716Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Pteropus_vampyrusone2one ENSPVAG00000002282Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Cavia_porcellusone2one ENSCPOG00000003180Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Dipodomys_ordiione2one ENSDORG00000008624Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P30935][hgnc]
Spermophilus_tridecemlineatusone2one ENSSTOG00000010878Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Ochotona_princepsone2one ENSOPRG00000014238Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Rattus_norvegicusone2one ENSRNOG00000007332Somatostatin receptor type 3 (SS3R) (SSR-28). [Source:UniProtKB/Swiss-Prot;Acc:P30936][hgnc]Sstr3
Mus_musculusone2one ENSMUSG00000044933Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P30935][hgnc]Sstr3
Ornithorhynchus_anatinusone2one ENSOANG00000013617Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Gallus_gallusone2one ENSGALG00000012457somatostatin receptor 3 [Source:RefSeq_peptide;Acc:NP_001019754][hgnc]SSTR3
Gasterosteus_aculeatusone2one ENSGACG00000014537Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Oryzias_latipesone2many ENSORLG00000001415Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000018823Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000011262Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Tetraodon_nigroviridisone2many ENSTNIG00000003494Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Takifugu_rubripesone2many ENSTRUG00000000013Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Takifugu_rubripesone2many ENSTRUG00000007737Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Oryzias_latipesone2many ENSORLG00000010790Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Xenopus_tropicalisone2one ENSXETG00000016039Somatostatin receptor type 3 (SS3R) (SSR-28) [Source:UniProtKB/Swiss-Prot;Acc:P32745][hgnc]
Anopheles_gambiaemany2many AGAP012268putative somatostatin receptor [Source:Anopheles_symbol;Acc:GPRSMS][hgnc]GPRSMS
Anopheles_gambiaemany2many AGAP010486putative allatostatin receptor 3 [Source:Anopheles_symbol;Acc:GPRALS3][hgnc]GPRALS3