Human-gpDB

	Human-gpDB
	A database of human GPCRs, G-proteins, Effectors and their interactions

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Summary sheet information for GPCR 'PEPTIDE P518 RECEPTORS_QRFPR_Homo sapiens'

Name

PEPTIDE P518 RECEPTORS_QRFPR_Homo sapiens

Description

RecName: Full=Pyroglutamylated RFamide peptide receptor;AltName: Full=Orexigenic neuropeptide QRFP receptor;AltName: Full=G-protein coupled receptor 103;AltName: Full=SP9155;AltName: Full=AQ27

Class

CLASS A

Family

PEPTIDE P518 RECEPTORS

Sub_family

QRFPR

type

Protein features link

Protein Information from Dasty2 DAS Client

GPCR, G-protein, Effector interaction

Visualizaton of GPCR, G-protein, Effector interaction at protein level

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Genes

Gene Location:

Chromosome	: 4
Gene Start	: 122469247
Gene End	: 122521631
Ensembl Contig View

Ensembl Genes:

ENSG00000186867

EMBL:

EMBL ID		Description
AB109629		Homo sapiens AQ27 mRNA for QRFP receptor, complete cds.
AF411117		Homo sapiens G protein-coupled receptor (GPR103) mRNA, complete cds.
BC128132		Homo sapiens G protein-coupled receptor 103, mRNA (cDNA clone IMAGE:40112419).
BC128133		Homo sapiens G protein-coupled receptor 103, mRNA (cDNA clone MGC:149217 IMAGE:40112420), complete cds.

EntrezGene:

ID		Description
GPR103		pyroglutamylated RFamide peptide receptor

RefSeq DNA:

ID		Description
NM_198179		Homo sapiens pyroglutamylated RFamide peptide receptor (QRFPR), mRNA.

UniGene:

ID		Description
Hs.368977		G protein-coupled receptor 103, mRNA (cDNA clone MGC:149217 IMAGE:40112420)

Proteins

Ensembl Proteins:

ENSP00000377948; ENSP00000335610

Entrez Proteins:

AAI28133.1; AAI28134.1; AAL26488.1; BAC98938.1

RefSeq Proteins:

ID		Description
NP_937822		G protein-coupled receptor 103 [Homo sapiens].

UniProt:

ID		Description
A1A4W0		UNKNOWN
A1A4W1		SubName: Full=GPR103 protein;
Q96P65		RecName: Full=Orexigenic neuropeptide QRFP receptor; AltName: Full=G-protein coupled receptor 103; AltName: Full=SP9155; AltName: Full=AQ27;

Domains

SMART:

- Hyperlink to SMART;

- Hyperlink to ENSEMBL

InterPro:

ID		Name
IPR000276		GPCR_Rhodpsn
IPR017452		GPCR_Rhodpsn_supfam
IPR000611		NPY_rcpt

Pfam:

ID		Description
7tm_1		7 transmembrane receptor (rhodopsin family)

Structure

PDB:

HSSP:

Description

PSSH:

ID		Description
A1A4W1		UNKNOWN
Q96P65		UNKNOWN

Diseases

OMIM:

OMIM ID		Name		Alt Name
606925		G PROTEIN-COUPLED RECEPTOR 103; GPR103		SP9155 AQ27

Gene Ontology

GO:

GO ID		Description
GO:0001584		rhodopsin-like receptor activity
GO:0004872		receptor activity
GO:0004946		bombesin receptor activity
GO:0004983		neuropeptide Y receptor activity
GO:0005886		plasma membrane
GO:0007165		signal transduction
GO:0007186		G-protein coupled receptor protein signaling pathway
GO:0008067		metabotropic glutamate, GABA-B-like receptor activity
GO:0008188		neuropeptide receptor activity
GO:0016020		membrane
GO:0016021		integral to membrane
GO:0016499		orexin receptor activity
GO:0045028		purinergic nucleotide receptor activity, G-protein coupled

Pathway

KEGG:

KEGG PATHWAY ID

Name

Panther:

Description

Chemicals

DrugBank:

Name

Synonyms

HMDB:

Name

Synonyms

Other GPCR resources

Links to other GPCR resources

GPCRDB | GPCR-OKB | GLIDA

Orthology

Orthology Relations:

Gene	Gene Description	Organism	Orthology type	Orthologs	Orthologs Description
ENSG00000186867	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65]	Pongo_pygmaeus	one2one	ENSPPYG00000015034	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Pan_troglodytes	one2one	ENSPTRG00000016406	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]GPR103
		Tarsius_syrichta	one2one	ENSTSYG00000010286	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Equus_caballus	one2one	ENSECAG00000010698	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Otolemur_garnettii	one2one	ENSOGAG00000000471	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Canis_familiaris	one2one	ENSCAFG00000004156	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]GPR103
		Cavia_porcellus	one2one	ENSCPOG00000001530	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Macaca_mulatta	one2one	ENSMMUG00000007974	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Oryctolagus_cuniculus	one2one	ENSOCUG00000000563	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Dasypus_novemcinctus	one2one	ENSDNOG00000018386	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Loxodonta_africana	one2one	ENSLAFG00000008559	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Bos_taurus	one2one	ENSBTAG00000008255	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]GPR103
		Ochotona_princeps	one2one	ENSOPRG00000005951	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Vicugna_pacos	one2one	ENSVPAG00000007440	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Procavia_capensis	one2one	ENSPCAG00000004587	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Erinaceus_europaeus	one2one	ENSEEUG00000008540	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Tupaia_belangeri	one2one	ENSTBEG00000015868	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Echinops_telfairi	one2one	ENSETEG00000007283	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Rattus_norvegicus	one2many	ENSRNOG00000006782	[hgnc]RGD1560028_predicted
		Rattus_norvegicus	one2many	ENSRNOG00000014414	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27). [Source:UniProtKB/Swiss-Prot;Acc:P83858][hgnc]Gpr103
		Mus_musculus	one2many	ENSMUSG00000058400	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:P83861][hgnc]Gpr103
		Sorex_araneus	one2one	ENSSARG00000008877	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Dipodomys_ordii	one2one	ENSDORG00000013419	[hgnc]
		Spermophilus_tridecemlineatus	one2one	ENSSTOG00000011128	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Ornithorhynchus_anatinus	one2one	ENSOANG00000015112	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]100082188
		Monodelphis_domestica	one2one	ENSMODG00000018939	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Gallus_gallus	one2one	ENSGALG00000011890	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]GPR103
		Myotis_lucifugus	one2one	ENSMLUG00000012941	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Xenopus_tropicalis	one2one	ENSXETG00000002104	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Danio_rerio	one2one	ENSDARG00000068422	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Oryzias_latipes	one2one	ENSORLG00000008962	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Gasterosteus_aculeatus	one2one	ENSGACG00000002317	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Takifugu_rubripes	one2one	ENSTRUG00000013374	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]
		Tetraodon_nigroviridis	one2one	ENSTNIG00000013150	Orexigenic neuropeptide QRFP receptor (G-protein coupled receptor 103) (SP9155) (AQ27) [Source:UniProtKB/Swiss-Prot;Acc:Q96P65][hgnc]