Human-gpDB    A database of human GPCRs, G-proteins, Effectors and their interactions

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	Summary sheet information for GPCR 'OLFACTORY RECEPTORS_OR2A1_Homo sapiens'
Name	OLFACTORY RECEPTORS_OR2A1_Homo sapiens
Description	RecName: Full=Olfactory receptor 2A1/2A42;AltName: Full=Olfactory receptor OR7-16;AltName: Full=Olfactory receptor OR7-19
Class	CLASS A
Family	OLFACTORY RECEPTORS
Sub_family	OR2A1
type
Protein features link	Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction	Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes	Gene Location: Chromosome : 7 Gene Start : 143559937 Gene End : 143560869 Ensembl Contig View Ensembl Genes: ENSG00000212807 EMBL: EMBL ID    Description AB065692    Homo sapiens gene for seven transmembrane helix receptor, complete cds, isolate:CBRC7TM_255. AF327904    Homo sapiens FKSG35 (FKSG35) mRNA, complete cds. AF399597    Homo sapiens clone OR2A1 olfactory receptor gene, partial cds. BK004217    TPA: Homo sapiens olfactory receptor OR7-16 gene, complete cds. BK004418    TPA: Homo sapiens olfactory receptor OR7-19 gene, complete cds. EntrezGene: ID    Description OR2A1    olfactory receptor, family 2, subfamily A, member 1 OR2A42    olfactory receptor, family 2, subfamily A, member 42 RefSeq DNA: ID    Description NM_001001802    Homo sapiens olfactory receptor, family 2, subfamily A, member 42 (OR2A42), mRNA. UniGene: ID    Description Hs.632027    Olfactory receptor, family 2, subfamily A, member 42 (OR2A42), mRNA
Proteins	Ensembl Proteins: ENSP00000375334 Entrez Proteins: AAG50283.1; AAK95082.1; BAC05915.1; DAA04615.1; DAA04816.1 RefSeq Proteins: ID    Description NP_001001802    olfactory receptor, family 2, subfamily A, member 42 [Homo sapiens]. NP_001005287    olfactory receptor, family 2, subfamily A, member 1 [Homo sapiens]. UniProt: ID    Description Q9BZC5    SubName: Full=FKSG35; Q8NGT9    UNKNOWN
Domains	SMART: - Hyperlink to SMART; - Hyperlink to ENSEMBL InterPro: ID    Name IPR000725    Olfact_rcpt IPR000276    GPCR_Rhodpsn IPR017452    GPCR_Rhodpsn_supfam Pfam: ID    Description 7tm_1    7 transmembrane receptor (rhodopsin family)
Structure	PDB: ID HSSP: ID    Description PSSH: ID    Description
Diseases	OMIM: OMIM ID    Name    Alt Name
Gene Ontology	GO: GO ID    Description GO:0001584    rhodopsin-like receptor activity GO:0004872    receptor activity GO:0004977    melanocortin receptor activity GO:0004984    olfactory receptor activity GO:0005886    plasma membrane GO:0006508    proteolysis GO:0007165    signal transduction GO:0007186    G-protein coupled receptor protein signaling pathway GO:0007608    sensory perception of smell GO:0008237    metallopeptidase activity GO:0008270    zinc ion binding GO:0016021    integral to membrane GO:0050896    response to stimulus
Pathway	KEGG: KEGG PATHWAY ID    Name hsa04740    Olfactory transduction hsa04740    Olfactory transduction Panther: ID    Description
Chemicals	DrugBank: ID    Name    Synonyms HMDB: ID    Name    Synonyms
Other GPCR resources	Links to other GPCR resources GPCRDB | GPCR-OKB | GLIDA
Orthology	Orthology Relations: Gene Gene Description Organism Orthology type Orthologs Orthologs Description ENSG00000212807 Olfactory receptor 2A42 (Olfactory receptor OR7-19) (Olfactory receptor OR7-16) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGT9] Pongo_pygmaeus one2many ENSPPYG00000018136 [hgnc] Macaca_mulatta one2many ENSMMUG00000030058 [hgnc] Microcebus_murinus one2many ENSMICG00000002261 [hgnc] Equus_caballus one2many ENSECAG00000021335 [hgnc]LOC100058194 Felis_catus one2many ENSFCAG00000018454 [hgnc] Tarsius_syrichta one2many ENSTSYG00000005716 [hgnc] Vicugna_pacos one2many ENSVPAG00000006727 [hgnc] Canis_familiaris many2many ENSCAFG00000003508 Olfactory receptor (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q70ZH9][hgnc]OR08A11 Canis_familiaris many2many ENSCAFG00000003506 [hgnc]LOC475516 Bos_taurus many2many ENSBTAG00000039361 [hgnc]LOC504233 Tupaia_belangeri one2many ENSTBEG00000000455 [hgnc] Bos_taurus many2many ENSBTAG00000038563 [hgnc] Mus_musculus many2many ENSMUSG00000061210 olfactory receptor 47 [Source:RefSeq_peptide;Acc:NP_666482][hgnc]Olfr47 Rattus_norvegicus many2many ENSRNOG00000033939 olfactory receptor Olr821 [Source:RefSeq_peptide;Acc:NP_001000842][hgnc]Olr821_predicted Mus_musculus many2many ENSMUSG00000059411 olfactory receptor 434 [Source:RefSeq_peptide;Acc:NP_666481][hgnc]Olfr434 Rattus_norvegicus many2many ENSRNOG00000031828 olfactory receptor Olr820 [Source:RefSeq_peptide;Acc:NP_001000974][hgnc]Olr820_predicted Mus_musculus many2many ENSMUSG00000048693 olfactory receptor 435 [Source:RefSeq_peptide;Acc:NP_666864][hgnc]Olfr435 Rattus_norvegicus many2many ENSRNOG00000005469 olfactory receptor Olr819 [Source:RefSeq_peptide;Acc:NP_001000843][hgnc]Olr819_predicted Monodelphis_domestica one2many ENSMODG00000001599 [hgnc]