Human-gpDB    A database of human GPCRs, G-proteins, Effectors and their interactions

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	Summary sheet information for GPCR 'OLFACTORY RECEPTORS_OR2A5_Homo sapiens'
Name	OLFACTORY RECEPTORS_OR2A5_Homo sapiens
Description	RecName: Full=Olfactory receptor 2A5;AltName: Full=Olfactory receptor 7-138/7-141; Short=OR7-138; Short=OR7-141
Class	CLASS A
Family	OLFACTORY RECEPTORS
Sub_family	OR2A5
type
Protein features link	Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction	Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes	Gene Location: Chromosome : 7 Gene Start : 143378428 Gene End : 143379363 Ensembl Contig View Ensembl Genes: ENSG00000221836 EMBL: EMBL ID    Description AC091768.4-201    UNKNOWN AC091768    Homo sapiens BAC clone RP11-703N5 from 7, complete sequence. AF399595    Homo sapiens clone OR2A5 olfactory receptor gene, partial cds. U86278    Homo sapiens olfactory receptor (OR7-138) gene, partial cds. U86281    Homo sapiens olfactory receptor (OR7-141) gene, partial cds. AC091768.4    UNKNOWN EntrezGene: ID    Description OR2A5    olfactory receptor, family 2, subfamily A, member 5 RefSeq DNA: ID    Description NM_012365    Homo sapiens olfactory receptor, family 2, subfamily A, member 5 (OR2A5), mRNA. UniGene: ID    Description Hs.553793    Olfactory receptor, family 2, subfamily A, member 5 (OR2A5), mRNA
Proteins	Ensembl Proteins: ENSP00000386208 Entrez Proteins: AAC39630.1; AAC39633.1; AAK95080.1 RefSeq Proteins: ID    Description NP_036497    olfactory receptor, family 2, subfamily A, member 5 [Homo sapiens]. UniProt: ID    Description Q96R48    RecName: Full=Olfactory receptor 2A5; AltName: Full=Olfactory receptor 7-138/7-141; Short=OR7-138; Short=OR7-141;
Domains	SMART: - Hyperlink to SMART; - Hyperlink to ENSEMBL InterPro: ID    Name IPR000725    Olfact_rcpt IPR000276    GPCR_Rhodpsn IPR017452    GPCR_Rhodpsn_supfam Pfam: ID    Description 7tm_1    7 transmembrane receptor (rhodopsin family)
Structure	PDB: ID HSSP: ID    Description PSSH: ID    Description
Diseases	OMIM: OMIM ID    Name    Alt Name
Gene Ontology	GO: GO ID    Description GO:0001584    rhodopsin-like receptor activity GO:0004872    receptor activity GO:0004977    melanocortin receptor activity GO:0004984    olfactory receptor activity GO:0005886    plasma membrane GO:0007165    signal transduction GO:0007186    G-protein coupled receptor protein signaling pathway GO:0007608    sensory perception of smell GO:0016021    integral to membrane GO:0045028    purinergic nucleotide receptor activity, G-protein coupled GO:0050896    response to stimulus
Pathway	KEGG: KEGG PATHWAY ID    Name hsa04740    Olfactory transduction Panther: ID    Description
Chemicals	DrugBank: ID    Name    Synonyms HMDB: ID    Name    Synonyms
Other GPCR resources	Links to other GPCR resources GPCRDB | GPCR-OKB | GLIDA
Orthology	Orthology Relations: Gene Gene Description Organism Orthology type Orthologs Orthologs Description ENSG00000221836 Olfactory receptor 2A5 (Olfactory receptor 7-138/7-141) (OR7-138) (OR7-141) [Source:UniProtKB/Swiss-Prot;Acc:Q96R48] Equus_caballus one2one ENSECAG00000006034 [hgnc]LOC100057377 Canis_familiaris one2one ENSCAFG00000003513 Putative olfactory receptor (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q28305][hgnc]TPCR71 Bos_taurus one2one ENSBTAG00000007400 [hgnc]LOC515772 Rattus_norvegicus one2one ENSRNOG00000005407 olfactory receptor Olr812 [Source:RefSeq_peptide;Acc:NP_001000847][hgnc]Olr812_predicted Mus_musculus one2one ENSMUSG00000043119 olfactory receptor 448 [Source:RefSeq_peptide;Acc:NP_666385][hgnc]Olfr448 Monodelphis_domestica one2many ENSMODG00000001599 [hgnc]