Human-gpDB    A database of human GPCRs, G-proteins, Effectors and their interactions

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	Summary sheet information for GPCR 'OLFACTORY RECEPTORS_OR2A12_Homo sapiens'
Name	OLFACTORY RECEPTORS_OR2A12_Homo sapiens
Description	RecName: Full=Olfactory receptor 2A12;AltName: Full=Olfactory receptor OR7-10
Class	CLASS A
Family	OLFACTORY RECEPTORS
Sub_family	OR2A12
type
Protein features link	Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction	Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes	Gene Location: Chromosome : 7 Gene Start : 143423134 Gene End : 143424066 Ensembl Contig View Ensembl Genes: ENSG00000221858 EMBL: EMBL ID    Description AB065694    Homo sapiens gene for seven transmembrane helix receptor, complete cds, isolate:CBRC7TM_257. BC136902    Homo sapiens olfactory receptor, family 2, subfamily A, member 12, mRNA (cDNA clone MGC:168516 IMAGE:9020893), complete cds. BK004419    TPA: Homo sapiens olfactory receptor OR7-10 gene, complete cds. CH236959    Homo sapiens chromosome 7 Scaffold16, whole genome shotgun sequence. CH878732    Homo sapiens 211000035831128 genomic scaffold, whole genome shotgun sequence. EntrezGene: ID    Description OR2A12    olfactory receptor, family 2, subfamily A, member 12 RefSeq DNA: ID    Description NM_001004135    Homo sapiens olfactory receptor, family 2, subfamily A, member 12 (OR2A12), mRNA. UniGene: ID    Description Hs.553708    Olfactory receptor, family 2, subfamily A, member 12, mRNA (cDNA clone MGC:168516 IMAGE:9020893)
Proteins	Ensembl Proteins: ENSP00000386174 Entrez Proteins: AAI36903.1; BAC05917.1; DAA04817.1; EAL23798.1; EAW55631.1 RefSeq Proteins: ID    Description NP_001004135    olfactory receptor, family 2, subfamily A, member 12 [Homo sapiens]. UniProt: ID    Description A4D2G4    SubName: Full=Olfactory receptor, family 2, subfamily A, member 12; Q8NGT7    RecName: Full=Olfactory receptor 2A12; AltName: Full=Olfactory receptor OR7-10;
Domains	SMART: - Hyperlink to SMART; - Hyperlink to ENSEMBL InterPro: ID    Name IPR000725    Olfact_rcpt IPR000276    GPCR_Rhodpsn IPR017452    GPCR_Rhodpsn_supfam Pfam: ID    Description 7tm_1    7 transmembrane receptor (rhodopsin family)
Structure	PDB: ID HSSP: ID    Description PSSH: ID    Description
Diseases	OMIM: OMIM ID    Name    Alt Name
Gene Ontology	GO: GO ID    Description GO:0001584    rhodopsin-like receptor activity GO:0004872    receptor activity GO:0004977    melanocortin receptor activity GO:0004984    olfactory receptor activity GO:0005886    plasma membrane GO:0007165    signal transduction GO:0007186    G-protein coupled receptor protein signaling pathway GO:0007608    sensory perception of smell GO:0016021    integral to membrane GO:0050896    response to stimulus
Pathway	KEGG: KEGG PATHWAY ID    Name hsa04740    Olfactory transduction Panther: ID    Description
Chemicals	DrugBank: ID    Name    Synonyms HMDB: ID    Name    Synonyms
Other GPCR resources	Links to other GPCR resources GPCRDB | GPCR-OKB | GLIDA
Orthology	Orthology Relations: Gene Gene Description Organism Orthology type Orthologs Orthologs Description ENSG00000221858 Olfactory receptor 2A12 (Olfactory receptor OR7-10) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGT7] Bos_taurus one2one ENSBTAG00000038201 Olfactory receptor 2A12 (Olfactory receptor OR7-10) [Source:UniProtKB/Swiss-Prot;Acc:Q8NGT7][hgnc]LOC505454 Canis_familiaris one2one ENSCAFG00000003511 Olfactory receptor family 2 subfamily A (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q6W6U8][hgnc] Mus_musculus one2one ENSMUSG00000073111 olfactory receptor 446 [Source:RefSeq_peptide;Acc:NP_666407][hgnc]Olfr446 Monodelphis_domestica one2many ENSMODG00000001599 [hgnc]