Human-gpDB    A database of human GPCRs, G-proteins, Effectors and their interactions

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	Summary sheet information for GPCR 'TASTE RECEPTORS_TAS2R40_Homo sapiens'
Name	TASTE RECEPTORS_TAS2R40_Homo sapiens
Description	RecName: Full=Taste receptor type 2 member 40; Short=T2R40;AltName: Full=T2R58;AltName: Full=G-protein coupled receptor 60
Class	CLASS C
Family	TASTE RECEPTORS
Sub_family	TAS2R40
type
Protein features link	Protein Information from Dasty2 DAS Client
GPCR, G-protein, Effector interaction	Visualizaton of GPCR, G-protein, Effector interaction at protein level
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Genes	Gene Location: Chromosome : 7 Gene Start : 142629294 Gene End : 142630265 Ensembl Contig View Ensembl Genes: ENSG00000221937 EMBL: EMBL ID    Description AB199167    Homo sapiens Hosa(Adygei)-T2R40 gene for bitter taste receptor T2R40, partial cds. AB199168    Homo sapiens Hosa(Japanese)-T2R40 gene for bitter taste receptor T2R40, partial cds. AB199169    Homo sapiens Hosa(Biaka)-T2R40 gene for bitter taste receptor T2R40, partial cds. AF494229    Homo sapiens candidate taste receptor TAS2R40 gene, complete cds. AY724957    Homo sapiens chromosome 7 taste receptor T2R40 gene, complete cds. BC101795    Homo sapiens taste receptor, type 2, member 40, mRNA (cDNA clone MGC:126844 IMAGE:8069301), complete cds. BC101797    Homo sapiens taste receptor, type 2, member 40, mRNA (cDNA clone MGC:126846 IMAGE:8069303), complete cds. CH236959    Homo sapiens chromosome 7 Scaffold16, whole genome shotgun sequence. CH471198    Homo sapiens 211000035830252 genomic scaffold, whole genome shotgun sequence. EntrezGene: ID    Description TAS2R40    taste receptor, type 2, member 40 RefSeq DNA: ID    Description NM_176882    Homo sapiens taste receptor, type 2, member 40 (TAS2R40), mRNA. UniGene: ID    Description Hs.352241    Taste receptor, type 2, member 40, mRNA (cDNA clone MGC:126844 IMAGE:8069301)
Proteins	Ensembl Proteins: ENSP00000386210 Entrez Proteins: AAI01796.1; AAI01798.1; AAM19320.1; AAU21153.1; BAD98041.1; BAD98042.1; BAD98043.1; EAL23782.1; EAW51882.1 RefSeq Proteins: ID    Description NP_795363    taste receptor, type 2, member 40 [Homo sapiens]. UniProt: ID    Description A4D2I2    RecName: Full=Taste receptor type 2; Q50KK5    RecName: Full=Taste receptor type 2; Flags: Fragment; Q50KK6    RecName: Full=Taste receptor type 2; Flags: Fragment; P59535    RecName: Full=Taste receptor type 2 member 40; Short=T2R40; AltName: Full=T2R58; AltName: Full=G-protein coupled receptor 60;
Domains	SMART: - Hyperlink to SMART; - Hyperlink to ENSEMBL InterPro: ID    Name IPR007960    TAS2_rcpt Pfam: ID    Description TAS2R    Mammalian taste receptor protein (TAS2R)
Structure	PDB: ID HSSP: ID    Description PSSH: ID    Description
Diseases	OMIM: OMIM ID    Name    Alt Name
Gene Ontology	GO: GO ID    Description GO:0004872    receptor activity GO:0004930    G-protein coupled receptor activity GO:0007165    signal transduction GO:0007186    G-protein coupled receptor protein signaling pathway GO:0016020    membrane GO:0016021    integral to membrane GO:0050896    response to stimulus GO:0050909    sensory perception of taste
Pathway	KEGG: KEGG PATHWAY ID    Name hsa04742    Taste transduction Panther: ID    Description
Chemicals	DrugBank: ID    Name    Synonyms HMDB: ID    Name    Synonyms
Other GPCR resources	Links to other GPCR resources GPCRDB | GPCR-OKB | GLIDA
Orthology	Orthology Relations: Gene Gene Description Organism Orthology type Orthologs Orthologs Description ENSG00000221937 Taste receptor type 2 member 40 (T2R40) (T2R58) (G-protein coupled receptor 60) [Source:UniProtKB/Swiss-Prot;Acc:P59535] Pan_troglodytes one2one ENSPTRG00000032460 Taste receptor type 2 member 40 (T2R40). [Source:UniProtKB/Swiss-Prot;Acc:Q646B1][hgnc]TAS2R40 Pongo_pygmaeus one2one ENSPPYG00000018112 Taste receptor type 2 member 40 (T2R40). [Source:UniProtKB/Swiss-Prot;Acc:Q645U5][hgnc] Macaca_mulatta one2one ENSMMUG00000005967 Bitter taste receptor T2R40 (Fragment). [Source:UniProtKB/TrEMBL;Acc:Q50KK1][hgnc] Equus_caballus one2one ENSECAG00000007725 Taste receptor type 2 member 40 (T2R40) (T2R58) (G-protein coupled receptor 60) [Source:UniProtKB/Swiss-Prot;Acc:P59535][hgnc] Canis_familiaris one2one ENSCAFG00000024884 Bitter taste receptor. [Source:UniProtKB/TrEMBL;Acc:Q2ABD0][hgnc]TAS2R40 Bos_taurus one2one ENSBTAG00000040040 Taste receptor type 2 member 40 (T2R40) (T2R58) (G-protein coupled receptor 60) [Source:UniProtKB/Swiss-Prot;Acc:P59535][hgnc] Ochotona_princeps one2one ENSOPRG00000018913 Taste receptor type 2 member 40 (T2R40) (T2R58) (G-protein coupled receptor 60) [Source:UniProtKB/Swiss-Prot;Acc:P59535][hgnc] Mus_musculus one2one ENSMUSG00000051917 Taste receptor type 2 member 40 (T2R40) (mT2R33) [Source:UniProtKB/Swiss-Prot;Acc:Q7TQB8][hgnc]Tas2r144 Rattus_norvegicus one2one ENSRNOG00000028130 Taste receptor type 2 member 40 (T2R40) (Taste receptor type 2 member 18) (T2R18). [Source:UniProtKB/Swiss-Prot;Acc:Q67ET2][hgnc]RGD1562314_predicted Cavia_porcellus one2one ENSCPOG00000026948 Taste receptor type 2 member 40 (T2R40) (T2R58) (G-protein coupled receptor 60) [Source:UniProtKB/Swiss-Prot;Acc:P59535][hgnc] Monodelphis_domestica one2one ENSMODG00000024329 bitter taste receptor Modo-T2R40 [Source:RefSeq_peptide;Acc:NP_001034961][hgnc]T2R40 Gallus_gallus one2many ENSGALG00000022908 Bitter taste receptor. [Source:UniProtKB/TrEMBL;Acc:Q2AB83][hgnc] Gallus_gallus one2many ENSGALG00000022710 Bitter taste receptor. [Source:UniProtKB/TrEMBL;Acc:Q2AB82][hgnc]