Human-gpDB

	Human-gpDB
	A database of human GPCRs, G-proteins, Effectors and their interactions

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Description

Entry page for Effector - 'SHC transforming protein 1-Homo sapiens'

Family	SHC transforming proteins
Sub-Family	SHC transforming proteins
Type	SHC transforming protein 1

Cross References:

References

UniProt	P29353 \| O15290 \| Q5T180 \| Q5T183 \| Q5T184 \| Q5T185 \| Q5T186 \| Q8N4K5
EMBL	X68148 \| U73377 \| Y09847 \| AK292143 \| AK315842 \| AL451085 \| AL451085 \| AL451085 \| AL451085 \| AL451085 \| CH471121 \| CH471121 \| CH471121 \| BC014158 \| BC033925
InterPro	IPR011993 \| IPR006019 \| IPR006020 \| IPR000980
PRODOM	PD000093
GENEID	6464
MIM	600560
PRINTS	PR00401 \| PR00629
PFAM	PF00640 \| PF00017

Details:

Details

Name	SHC transforming protein 1-Homo sapiens
Description	RecName: Full=SHC-transforming protein 1;AltName: Full=Src homology 2 domain-containing-transforming protein C1; Short=SH2 domain protein C1
Species	Homo sapiens
Common Name	Human
NCBI Taxonomy	9606
Gene	SHC1 \| SHC,SHC
Function	Signaling adapter that couples activated growth factors receptors to signaling pathway
Fragment	0
Sequence	MDLLPPKPKYNPLRNESLSSLEEGASGSTPPEELPSPSASSLGPILPPLPGDDSPTTLCS FFPRMSNLRLANPAGGRPGSKGEPGRAADDGEGIVGAAMPDSGPLPLLQDMNKLSGGGGR RTRVEGGQLGGEEWTRHGSFVNKPTRGWLHPNDKVMGPGVSYLVRYMGCVEVLQSMRALD FNTRTQVTREAISLVCEAVPGAKGATRRRKPCSRPLSSILGRSNLKFAGMPITLTVSTSS LNLMAADCKQIIANHHMQSISFASGGDPDTAEYVAYVAKDPVNQRACHILECPEGLAQDV ISTIGQAFELRFKQYLRNPPKLVTPHDRMAGFDGSAWDEEEEEPPDHQYYNDFPGKEPPL GGVVDMRLREGAAPGAARPTAPNAQTPSHLGATLPVGQPVGGDPEVRKQMPPPPPCPGRE LFDDPSYVNVQNLDKARQAVGGAGPPNPAINGSAPRDLFDMKPFEDALRVPPPPQSVSMA EQLRGEPWFHGKLSRREAEALLQLNGDFLVRESTTTPGQYVLTGLQSGQPKHLLLVDPEG VVRTKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERKL

Interacting with G-proteins:

G-proteins

No	Name	Regulation	PubMed
1	Ggamma-8_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
2	Ggamma-4_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
3	Ggamma-5_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
4	Gbeta-4_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
5	Ggamma-11_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
6	Gbeta-5_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
7	Gbeta-1_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
8	Ggamma-2_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
9	Gbeta-like_Homo sapiens_1	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
10	Ggamma-t1_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
11	Ggamma-10_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
12	Ggamma-12_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
13	Ggamma-13_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
14	Ggamma-t2_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
15	Gbeta-3_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
16	Ggamma-7_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
17	Gbeta-like_Homo sapiens_2	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
18	Gbeta-2_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118
19	Ggamma-3_Homo sapiens	Stimulation(indirect activation of MAPK)	15251227 \| 14671004 \| 7568118

GPCR, G-protein, Effector interaction

Visualizaton of GPCR, G-protein, Effector interaction at protein level