Human-gpDB

	Human-gpDB
	A database of human GPCRs, G-proteins, Effectors and their interactions

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Description

Entry page for Effector - 'Dynamin 1-Homo sapiens'

Family	Dynamins
Sub-Family	Dynamins
Type	Dynamin 1

Cross References:

References

UniProt	Q05193 \| A6NLM6 \| Q5SYX0 \| Q5SYX2 \| Q6P3T6 \| Q86VD2
EMBL	L07807 \| L07808 \| L07809 \| L07810 \| AL590708 \| AL590708 \| BC050279 \| BC063850
InterPro	IPR000375 \| IPR001401 \| IPR019762 \| IPR003130 \| IPR011993 \| IPR001849
PRODOM
GENEID	1759
MIM	602377
PRINTS	PR00195
PFAM	PF01031 \| PF00350 \| PF02212 \| PF00169

Details:

Details

Name	Dynamin 1-Homo sapiens
Description	RecName: Full=Dynamin-1; EC=3.6.5.5
Species	Homo sapiens
Common Name	Human
NCBI Taxonomy	9606
Gene	DNM1 \| DN
Function	Microtubule-associated force-producing protein involveds in producing microtubule bundles and able to bind and hydrolyzes GTP
Fragment	0
Sequence	MGNRGMEDLIPLVNRLQDAFSAIGQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRG SGIVTRRPLVLQLVNATTEYAEFLHCKGKKFTDFEEVRLEIEAETDRVTGTNKGISPVPI NLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANSD LANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDARDVLENKLLPLRRGYIGVVNRSQK DIDGKKDITAALAAERKFFLSHPSYRHLADRMGTPYLQKVLNQQLTNHIRDTLPGLRNKL QSQLLSIEKEVEEYKNFRPDDPARKTKALLQMVQQFAVDFEKRIEGSGDQIDTYELSGGA RINRIFHERFPFELVKMEFDEKELRREISYAIKNIHGIRTGLFTPDMAFETIVKKQVKKI REPCLKCVDMVISELISTVRQCTKKLQQYPRLREEMERIVTTHIREREGRTKEQVMLLID IELAYMNTNHEDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKGWLTINNIGIMKGGSKE YWFVLTAENLSWYKDDEEKEKKYMLSVDNLKLRDVEKGFMSSKHIFALFNTEQRNVYKDY RQLELACETQEEVDSWKASFLRAGVYPERVGDKEKASETEENGSDSFMHSMDPQLERQVE TIRNLVDSYMAIVNKTVRDLMPKTIMHLMINNTKEFIFSELLANLYSCGDQNTLMEESAE QAQRRDEMLRMYHALKEALSIIGDINTTTVSTPMPPPVDDSWLQVQSVPAGRRSPTSSPT PQRRAPAVPPARPGSRGPAPGPPPAGSALGGAPPVPSRPGASPDPFGPPPQVPSRPNRAP PGVPSRSGQASPSRPESPRPPFDL

Interacting with G-proteins:

G-proteins

No	Name	Regulation	PubMed
1	Ggamma-8_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
2	Ggamma-4_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
3	Ggamma-5_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
4	Gbeta-4_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
5	Ggamma-11_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
6	Gbeta-5_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
7	Gbeta-1_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
8	Ggamma-2_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
9	Gbeta-like_Homo sapiens_1	Increased GTPase activity	15251227 \| 14671004
10	Ggamma-t1_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
11	Ggamma-10_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
12	Ggamma-12_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
13	Ggamma-13_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
14	Ggamma-t2_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
15	Gbeta-3_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
16	Ggamma-7_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
17	Gbeta-like_Homo sapiens_2	Increased GTPase activity	15251227 \| 14671004
18	Gbeta-2_Homo sapiens	Increased GTPase activity	15251227 \| 14671004
19	Ggamma-3_Homo sapiens	Increased GTPase activity	15251227 \| 14671004

GPCR, G-protein, Effector interaction

Visualizaton of GPCR, G-protein, Effector interaction at protein level