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Description Entry page for GPCR - 'GLUCAGON RECEPTORS_GCG_Homo sapiens'
ClassCLASS B
FamilyGLUCAGON RECEPTORS
Sub-FamilyGCG
Cross References:
References
UniProtP47871 | Q2M3M5
EMBLU03469 | L20316 | BC104854 | BC112041 | L24751
InterProIPR017981 | IPR001879 | IPR003291 | IPR003290 | IPR000832 | IPR017983
PRODOM
GENEID2642
MIM138033
PRINTSPR01353 | PR01354 | PR00249
PFAMPF00002 | PF02793
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameGLUCAGON RECEPTORS_GCG_Homo sapiens
DescriptionRecName: Full=Glucagon receptor; Short=GL-R;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGCG
FunctionThis is a receptor for glucagon which plays a centrals role in regulating the level of blood glucose by controlling thes rate of hepatic glucose production and insulin secretion
Fragment0
Sequence
MPPCQPQRPLLLLLLLLACQPQVPSAQVMDFLFEKWKLYGDQCHHNLSLLPPPTELVCNR
TFDKYSCWPDTPANTTANISCPWYLPWHHKVQHRFVFKRCGPDGQWVRGPRGQPWRDASQ
CQMDGEEIEVQKEVAKMYSSFQVMYTVGYSLSLGALLLALAILGGLSKLHCTRNAIHANL
FASFVLKASSVLVIDGLLRTRYSQKIGDDLSVSTWLSDGAVAGCRVAAVFMQYGIVANYC
WLLVEGLYLHNLLGLATLPERSFFSLYLGIGWGAPMLFVVPWAVVKCLFENVQCWTSNDN
MGFWWILRFPVFLAILINFFIFVRIVQLLVAKLRARQMHHTDYKFRLAKSTLTLIPLLGV
HEVVFAFVTDEHAQGTLRSAKLFFDLFLSSFQGLLVAVLYCFLNKEVQSELRRRWHRWRL
GKVLWEERNTSNHRASSSPGHGPPSKELQFGRGGGSQDSSAETPLAGGLPRLAESPF
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-s_Homo sapiens_2Gs8144028
2Galpha-s_Homo sapiens_1Gs8144028
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level