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Description Entry page for GPCR - 'PARATHYROID HORMONE RECEPTORS_PTH1_Homo sapiens'
ClassCLASS B
FamilyPARATHYROID HORMONE RECEPTORS
Sub-FamilyPTH1
Cross References:
References
UniProtQ03431 | Q2M1U3
EMBLL04308 | X68596 | U22409 | U22401 | U22402 | U22403 | U22404 | U22405 | U22406 | U22407 | U22408 | U17418 | AY449732 | BC112221 | BC112247
InterProIPR017981 | IPR001879 | IPR002170 | IPR000832 | IPR017983
PRODOM
GENEID5745
MIM125350 | 156400 | 166000 | 168468 | 215045 | 600002
PRINTSPR00249 | PR00393
PFAMPF00002 | PF02793
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NamePARATHYROID HORMONE RECEPTORS_PTH1_Homo sapiens
DescriptionRecName: Full=Parathyroid hormone/parathyroid hormone-related peptide receptor;AltName: Full=Parathyroid hormone 1 receptor; Short=PTH1 receptor;AltName: Full=PTH/PTHrP type I receptor; Short=PTH/PTHr receptor;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GenePTH1R | PTHR,PTHR
FunctionThis is a receptor for parathyroid hormone and fors parathyroid hormone-related peptide
Fragment0
Sequence
MGTARIAPGLALLLCCPVLSSAYALVDADDVMTKEEQIFLLHRAQAQCEKRLKEVLQRPA
SIMESDKGWTSASTSGKPRKDKASGKLYPESEEDKEAPTGSRYRGRPCLPEWDHILCWPL
GAPGEVVAVPCPDYIYDFNHKGHAYRRCDRNGSWELVPGHNRTWANYSECVKFLTNETRE
REVFDRLGMIYTVGYSVSLASLTVAVLILAYFRRLHCTRNYIHMHLFLSFMLRAVSIFVK
DAVLYSGATLDEAERLTEEELRAIAQAPPPPATAAAGYAGCRVAVTFFLYFLATNYYWIL
VEGLYLHSLIFMAFFSEKKYLWGFTVFGWGLPAVFVAVWVSVRATLANTGCWDLSSGNKK
WIIQVPILASIVLNFILFINIVRVLATKLRETNAGRCDTRQQYRKLLKSTLVLMPLFGVH
YIVFMATPYTEVSGTLWQVQMHYEMLFNSFQGFFVAIIYCFCNGEVQAEIKKSWSRWTLA
LDFKRKARSGSSSYSYGPMVSHTSVTNVGPRVGLGLPLSPRLLPTATTNGHPQLPGHAKP
GTPALETLETTPPAMAAPKDDGFLNGSCSGLDEEASGPERPPALLQEEWETVM
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-s_Homo sapiens_2Gs15694400
2Galpha-s_Homo sapiens_1Gs15694400
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level