Human-gpDB

	Human-gpDB
	A database of human GPCRs, G-proteins, Effectors and their interactions

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Description

Entry page for GPCR - 'MELANOCORTIN RECEPTORS_MC1_Homo sapiens'

Class	CLASS A
Family	MELANOCORTIN RECEPTORS
Sub-Family	MC1

Cross References:

References

UniProt	Q01726 \| Q66K38 \| Q8WWX6 \| Q8WWX7 \| Q96I33 \| Q96RU4 \| Q9UBF7 \| Q9UN58
EMBL	X65634 \| X67594 \| AF153431 \| AF153432 \| AF153433 \| AF153434 \| AF153435 \| AF153436 \| AF153437 \| AF326275 \| AF263461 \| AY046528 \| AY046529 \| AB241548 \| AY225228 \| AF514787 \| BC007856 \| BC080622
InterPro	IPR000276 \| IPR017452 \| IPR001671 \| IPR000761
PRODOM
GENEID	4157
MIM	155555 \| 266300
PRINTS	PR00237 \| PR00534 \| PR00536
PFAM	PF00001
Other GPCR resources	GPCRDB \| GPCR-OKB \| GLIDA

Details:

Details

Name	MELANOCORTIN RECEPTORS_MC1_Homo sapiens
Description	RecName: Full=Melanocyte-stimulating hormone receptor; Short=MSH-R;AltName: Full=Melanotropin receptor;AltName: Full=Melanocortin receptor 1;AltName: Full=MC1-R
Species	Homo sapiens
Common Name	Human
NCBI Taxonomy	9606
Gene	MC1R \| MSH
Function	Receptor for MSH (alpha, beta and gamma) and ACTH
Fragment	0
Sequence	MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVV ATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVI DVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFI AYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGA VTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAF HSQELRRTLKEVLTCSW

Interacting with G-proteins:

G-proteins

No	Name	Coupling	PubMed
1	Galpha-s_Homo sapiens_2	Gs	1516719
2	Galpha-s_Homo sapiens_1	Gs	1516719

GPCR, G-protein, Effector interaction

Visualizaton of GPCR, G-protein, Effector interaction at protein level