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Description Entry page for GPCR - 'CALCIUM-SENSING RECEPTORS_GPRC6_Homo sapiens'
ClassCLASS C
FamilyCALCIUM-SENSING RECEPTORS
Sub-FamilyGPRC6
Cross References:
References
UniProtQ5T6X5 | Q6JK43 | Q6JK44 | Q8NGU8 | Q8NHZ9 | Q8TDT6
EMBLAY435125 | AY435126 | AY435127 | AF502962 | AL354716 | AB065680 | AB083615
InterProIPR001828 | IPR000337 | IPR017978 | IPR000068 | IPR017979 | IPR011500
PRODOM
GENEID222545
MIM
PRINTSPR00592 | PR00248
PFAMPF00003 | PF01094 | PF07562
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameCALCIUM-SENSING RECEPTORS_GPRC6_Homo sapiens
DescriptionRecName: Full=G-protein coupled receptor family C group 6 member A; Short=hGPRC6A;AltName: Full=G-protein coupled receptor 33; Short=hGPCR33;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGPRC6A | GPCR3
FunctionReceptor that is activated by both amino acids ands extracellular concentration of calcium ions
Fragment0
Sequence
MAFLIILITCFVIILATSQPCQTPDDFVAATSPGHIIIGGLFAIHEKMLSSEDSPRRPQI
QECVGFEISVFLQTLAMIHSIEMINNSTLLPGVKLGYEIYDTCTEVTVAMAATLRFLSKF
NCSRETVEFKCDYSSYMPRVKAVIGSGYSEITMAVSRMLNLQLMPQVGYESTAEILSDKI
RFPSFLRTVPSDFHQIKAMAHLIQKSGWNWIGIITTDDDYGRLALNTFIIQAEANNVCIA
FKEVLPAFLSDNTIEVRINRTLKKIILEAQVNVIVVFLRQFHVFDLFNKAIEMNINKMWI
ASDNWSTATKITTIPNVKKIGKVVGFAFRRGNISSFHSFLQNLHLLPSDSHKLLHEYAMH
LSACAYVKDTDLSQCIFNHSQRTLAYKANKAIERNFVMRNDFLWDYAEPGLIHSIQLAVF
ALGYAIRDLCQARDCQNPNAFQPWELLGVLKNVTFTDGWNSFHFDAHGDLNTGYDVVLWK
EINGHMTVTKMAEYDLQNDVFIIPDQETKNEFRNLKQIQSKCSKECSPGQMKKTTRSQHI
CCYECQNCPENHYTNQTDMPHCLLCNNKTHWAPVRSTMCFEKEVEYLNWNDSLAILLLIL
SLLGIIFVLVVGIIFTRNLNTPVVKSSGGLRVCYVILLCHFLNFASTSFFIGEPQDFTCK
TRQTMFGVSFTLCISCILTKSLKILLAFSFDPKLQKFLKCLYRPILIIFTCTGIQVVICT
LWLIFAAPTVEVNVSLPRVIILECEEGSILAFGTMLGYIAILAFICFIFAFKGKYENYNE
AKFITFGMLIYFIAWITFIPIYATTFGKYVPAVEIIVILISNYGILYCTFIPKCYVIICK
QEINTKSAFLKMIYSYSSHSVSSIALSPASLDSMSGNVTMTNPSSSGKSATWQKSKDLQA
QAFAHICRENATSVSKTLPRKRMSSI
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o8255296
2Galpha-q_Homo sapiensGq/118255296
3Galpha-13_Homo sapiensG12/138255296
4Galpha-i2_Homo sapiensGi/o8255296
5Galpha-z_Homo sapiensGi/o8255296
6Galpha-12_Homo sapiensG12/138255296
7Galpha-i3_Homo sapiensGi/o8255296
8Galpha-14_Homo sapiensGq/118255296
9Galpha-11_Homo sapiensGq/118255296
10Galpha-o_Homo sapiensGi/o8255296
11Galpha-15_Homo sapiensGq/118255296
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level