| Description |
Entry page for GPCR - 'NICOTINIC ACID RECEPTORS_NIACR1_Homo sapiens'
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Cross References: |
| References |
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Details: |
| Details |
| Name | NICOTINIC ACID RECEPTORS_NIACR1_Homo sapiens |
| Description | RecName: Full=Niacin receptor 1;AltName: Full=Nicotinic acid receptor;AltName: Full=G-protein coupled receptor 109A;AltName: Full=G-protein coupled receptor HM74A |
| Species | Homo sapiens |
| Common Name | Human |
| NCBI Taxonomy | 9606 |
| Gene | NIACR1 | GPR109A,HM74 |
| Function | Acts as a high affinity receptor for both nicotinic acids (also known as niacin) and (D)-beta-hydroxybutyrate and mediatess increased adiponectin secretion and decreased lipolysis throughs G(i)-protein-mediated inhibition of adenylyl cyclase |
| Fragment | 0 |
| Sequence | MNRHHLQDHFLEIDKKNCCVFRDDFIVKVLPPVLGLEFIFGLLGNGLALWIFCFHLKSWK
SSRIFLFNLAVADFLLIICLPFLMDNYVRRWDWKFGDIPCRLMLFMLAMNRQGSIIFLTV
VAVDRYFRVVHPHHALNKISNRTAAIISCLLWGITIGLTVHLLKKKMPIQNGGANLCSSF
SICHTFQWHEAMFLLEFFLPLGIILFCSARIIWSLRQRQMDRHAKIKRAITFIMVVAIVF
VICFLPSVVVRIRIFWLLHTSGTQNCEVYRSVDLAFFITLSFTYMNSMLDPVVYYFSSPS
FPNFFSTLINRCLQRKMTGEPDNNRSTSVELTGDPNKTRGAPEALMANSGEPWSPSYLGP
TSP
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Interacting with G-proteins: |
| G-proteins |
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| GPCR, G-protein, Effector interaction |
Visualizaton of GPCR, G-protein, Effector interaction at protein level
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