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Description Entry page for GPCR - 'METABOTROPIC GLUTAMATE RECEPTORS_MGLU6_Homo sapiens'
ClassCLASS C
FamilyMETABOTROPIC GLUTAMATE RECEPTORS
Sub-FamilyMGLU6
Cross References:
References
UniProtO15303
EMBLU82083 | AC104117
InterProIPR001828 | IPR000337 | IPR017978 | IPR017979 | IPR000162 | IPR000112 | IPR011500
PRODOM
GENEID2916
MIM257270 | 604096
PRINTSPR00248 | PR01056 | PR00593
PFAMPF00003 | PF01094 | PF07562
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameMETABOTROPIC GLUTAMATE RECEPTORS_MGLU6_Homo sapiens
DescriptionRecName: Full=Metabotropic glutamate receptor 6; Short=mGluR6;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGRM6 | GPRC1F,MGLUR
FunctionReceptor for glutamate
Fragment0
Sequence
MARPRRAREPLLVALLPLAWLAQAGLARAAGSVRLAGGLTLGGLFPVHARGAAGRACGQL
KKEQGVHRLEAMLYALDRVNADPELLPGVRLGARLLDTCSRDTYALEQALSFVQALIRGR
GDGDEVGVRCPGGVPPLRPAPPERVVAVVGASASSVSIMVANVLRLFAIPQISYASTAPE
LSDSTRYDFFSRVVPPDSYQAQAMVDIVRALGWNYVSTLASEGNYGESGVEAFVQISREA
GGVCIAQSIKIPREPKPGEFSKVIRRLMETPNARGIIIFANEDDIRRVLEAARQANLTGH
FLWVGSDSWGAKTSPILSLEDVAVGAITILPKRASIDGFDQYFMTRSLENNRRNIWFAEF
WEENFNCKLTSSGTQSDDSTRKCTGEERIGRDSTYEQEGKVQFVIDAVYAIAHALHSMHQ
ALCPGHTGLCPAMEPTDGRMLLQYIRAVRFNGSAGTPVMFNENGDAPGRYDIFQYQATNG
SASSGGYQAVGQWAETLRLDVEALQWSGDPHEVPSSLCSLPCGPGERKKMVKGVPCCWHC
EACDGYRFQVDEFTCEACPGDMRPTPNHTGCRPTPVVRLSWSSPWAAPPLLLAVLGIVAT
TTVVATFVRYNNTPIVRASGRELSYVLLTGIFLIYAITFLMVAEPGAAVCAARRLFLGLG
TTLSYSALLTKTNRIYRIFEQGKRSVTPPPFISPTSQLVITFSLTSLQVVGMIAWLGARP
PHSVIDYEEQRTVDPEQARGVLKCDMSDLSLIGCLGYSLLLMVTCTVYAIKARGVPETFN
EAKPIGFTMYTTCIIWLAFVPIFFGTAQSAEKIYIQTTTLTVSLSLSASVSLGMLYVPKT
YVILFHPEQNVQKRKRSLKATSTVAAPPKGEDAEAHK
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o8389366
2Galpha-i3_Homo sapiensGi/o8389366
3Galpha-i2_Homo sapiensGi/o8389366
4Galpha-o_Homo sapiensGi/o8389366
5Galpha-z_Homo sapiensGi/o8389366
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level