Quick search:







Description Entry page for GPCR - 'METABOTROPIC GLUTAMATE RECEPTORS_MGLU8_Homo sapiens'
ClassCLASS C
FamilyMETABOTROPIC GLUTAMATE RECEPTORS
Sub-FamilyMGLU8
Cross References:
References
UniProtO00222 | A4D0Y3 | B0FZ74 | B0M0L0 | O15493 | O95945 | O95946 | Q3MIV9
EMBLU95025 | U92459 | AJ236921 | AJ236922 | AY608335 | EU432125 | EU368948 | CH236947 | BC093725 | BC101675
InterProIPR001828 | IPR000337 | IPR017978 | IPR017979 | IPR000162 | IPR000144 | IPR011500
PRODOM
GENEID2918
MIM601116
PRINTSPR00248 | PR01058 | PR00593
PFAMPF00003 | PF01094 | PF07562
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameMETABOTROPIC GLUTAMATE RECEPTORS_MGLU8_Homo sapiens
DescriptionRecName: Full=Metabotropic glutamate receptor 8; Short=mGluR8;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGRM8 | GPRC1H,MGLUR
FunctionReceptor for glutamate
Fragment0
Sequence
MVCEGKRSASCPCFFLLTAKFYWILTMMQRTHSQEYAHSIRVDGDIILGGLFPVHAKGER
GVPCGELKKEKGIHRLEAMLYAIDQINKDPDLLSNITLGVRILDTCSRDTYALEQSLTFV
QALIEKDASDVKCANGDPPIFTKPDKISGVIGAAASSVSIMVANILRLFKIPQISYASTA
PELSDNTRYDFFSRVVPPDSYQAQAMVDIVTALGWNYVSTLASEGNYGESGVEAFTQISR
EIGGVCIAQSQKIPREPRPGEFEKIIKRLLETPNARAVIMFANEDDIRRILEAAKKLNQS
GHFLWIGSDSWGSKIAPVYQQEEIAEGAVTILPKRASIDGFDRYFRSRTLANNRRNVWFA
EFWEENFGCKLGSHGKRNSHIKKCTGLERIARDSSYEQEGKVQFVIDAVYSMAYALHNMH
KDLCPGYIGLCPRMSTIDGKELLGYIRAVNFNGSAGTPVTFNENGDAPGRYDIFQYQITN
KSTEYKVIGHWTNQLHLKVEDMQWAHREHTHPASVCSLPCKPGERKKTVKGVPCCWHCER
CEGYNYQVDELSCELCPLDQRPNMNRTGCQLIPIIKLEWHSPWAVVPVFVAILGIIATTF
VIVTFVRYNDTPIVRASGRELSYVLLTGIFLCYSITFLMIAAPDTIICSFRRVFLGLGMC
FSYAALLTKTNRIHRIFEQGKKSVTAPKFISPASQLVITFSLISVQLLGVFVWFVVDPPH
IIIDYGEQRTLDPEKARGVLKCDISDLSLICSLGYSILLMVTCTVYAIKTRGVPETFNEA
KPIGFTMYTTCIIWLAFIPIFFGTAQSAEKMYIQTTTLTVSMSLSASVSLGMLYMPKVYI
IIFHPEQNVQKRKRSFKAVVTAATMQSKLIQKGNDRPNGEVKSELCESLETNTSSTKTTY
ISYSNHSI
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o9473604
2Galpha-i3_Homo sapiensGi/o9473604
3Galpha-i2_Homo sapiensGi/o9473604
4Galpha-o_Homo sapiensGi/o9473604
5Galpha-z_Homo sapiensGi/o9473604
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level