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Description Entry page for GPCR - 'CALCITONIN RECEPTORS_CGRP_Homo sapiens'
ClassCLASS B
FamilyCALCITONIN RECEPTORS
Sub-FamilyCGRP
Cross References:
References
UniProtQ16602 | A8K6G5 | A8KAD3 | Q53S02 | Q53TS5
EMBLL76380 | U17473 | AY389506 | AK291630 | AK292998 | AC007319 | AC074020
InterProIPR003287 | IPR017981 | IPR003289 | IPR001879 | IPR000832 | IPR017983
PRODOM
GENEID10203
MIM114190
PRINTSPR01351 | PR01350 | PR00249
PFAMPF00002 | PF02793
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameCALCITONIN RECEPTORS_CGRP_Homo sapiens
DescriptionRecName: Full=Calcitonin gene-related peptide type 1 receptor; Short=CGRP type 1 receptor;AltName: Full=Calcitonin receptor-like receptor;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneCALCRL | CGRP
FunctionReceptor for calcitonin-gene-related peptide (CGRP)s together with RAMP1 and receptor for adrenomedullin together withs RAMP2 or RAMP3 (By similarity)
Fragment0
Sequence
MEKKCTLNFLVLLPFFMILVTAELEESPEDSIQLGVTRNKIMTAQYECYQKIMQDPIQQA
EGVYCNRTWDGWLCWNDVAAGTESMQLCPDYFQDFDPSEKVTKICDQDGNWFRHPASNRT
WTNYTQCNVNTHEKVKTALNLFYLTIIGHGLSIASLLISLGIFFYFKSLSCQRITLHKNL
FFSFVCNSVVTIIHLTAVANNQALVATNPVSCKVSQFIHLYLMGCNYFWMLCEGIYLHTL
IVVAVFAEKQHLMWYYFLGWGFPLIPACIHAIARSLYYNDNCWISSDTHLLYIIHGPICA
ALLVNLFFLLNIVRVLITKLKVTHQAESNLYMKAVRATLILVPLLGIEFVLIPWRPEGKI
AEEVYDYIMHILMHFQGLLVSTIFCFFNGEVQAILRRNWNQYKIQFGNSFSNSEALRSAS
YTVSTISDGPGYSHDCPSEHLNGKSIHDIENVLLKPENLYN
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-11_Homo sapiensGq/118732687
2Galpha-14_Homo sapiensGq/118732687
3Galpha-q_Homo sapiensGq/118732687
4Galpha-s_Homo sapiens_2Gs1331173
5Galpha-s_Homo sapiens_1Gs1331173
6Galpha-15_Homo sapiensGq/118732687
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level