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Description Entry page for GPCR - 'CORTICOTROPIN RECEPTORS_CRF1_Homo sapiens'
ClassCLASS B
FamilyCORTICOTROPIN RECEPTORS
Sub-FamilyCRF1
Cross References:
References
UniProtP34998 | Q13008 | Q9UK64
EMBLL23333 | L23332 | X72304 | AF039523 | AF039510 | AF039511 | AF039512 | AF039513 | AF039514 | AF039515 | AF039516 | AF039517 | AF039518 | AF039519 | AF039520 | AF039521 | AF039522 | U16273 | AF180301 | AY457172
InterProIPR017981 | IPR003052 | IPR003051 | IPR001879 | IPR000832 | IPR017983
PRODOM
GENEID1394
MIM122561
PRINTSPR01279 | PR01280 | PR00249
PFAMPF00002 | PF02793
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameCORTICOTROPIN RECEPTORS_CRF1_Homo sapiens
DescriptionRecName: Full=Corticotropin-releasing factor receptor 1; Short=CRF-R; Short=CRF1;AltName: Full=Corticotropin-releasing hormone receptor 1; Short=CRH-R 1;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneCRHR1 | CRFR,CRFR1,CRH
FunctionThis is a receptor for corticotropin releasing factor
Fragment0
Sequence
MGGHPQLRLVKALLLLGLNPVSASLQDQHCESLSLASNISGLQCNASVDLIGTCWPRSPA
GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHVAV
IINYLGHCISLVALLVAFVLFLRLRPGCTHWGDQADGALEVGAPWSGAPFQVRRSIRCLR
NIIHWNLISAFILRNATWFVVQLTMSPEVHQSNVGWCRLVTAAYNYFHVTNFFWMFGEGC
YLHTAIVLTYSTDRLRKWMFICIGWGVPFPIIVAWAIGKLYYDNEKCWFGKRPGVYTDYI
YQGPMILVLLINFIFLFNIVRILMTKLRASTTSETIQYRKAVKATLVLLPLLGITYMLFF
VNPGEDEVSRVVFIYFNSFLESFQGFFVSVFYCFLNSEVRSAIRKRWHRWQDKHSIRARV
ARAMSIPTSPTRVSFHSIKQSTAV
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-s_Homo sapiens_2Gs1280419
2Galpha-s_Homo sapiens_1Gs1280419
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level