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Description Entry page for GPCR - 'PROTEINASE-ACTIVATED RECEPTORS_PAR1_Homo sapiens'
ClassCLASS A
FamilyPROTEINASE-ACTIVATED RECEPTORS
Sub-FamilyPAR1
Cross References:
References
UniProtP25116 | Q96RF7 | Q9BUN4
EMBLM62424 | AF391809 | BC002464 | BC051909
InterProIPR000276 | IPR017452 | IPR003912 | IPR000935
PRODOM
GENEID2149
MIM187930
PRINTSPR00237 | PR01428 | PR00908
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NamePROTEINASE-ACTIVATED RECEPTORS_PAR1_Homo sapiens
DescriptionRecName: Full=Proteinase-activated receptor 1; Short=PAR-1;AltName: Full=Thrombin receptor;AltName: Full=Coagulation factor II receptor;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneF2R | CF2R,PAR1,T
FunctionHigh affinity receptor for activated thrombin coupled tos G proteins that stimulate phosphoinositide hydrolysis
Fragment0
Sequence
MGPRRLLLVAACFSLCGPLLSARTRARRPESKATNATLDPRSFLLRNPNDKYEPFWEDEE
KNESGLTEYRLVSINKSSPLQKQLPAFISEDASGYLTSSWLTLFVPSVYTGVFVVSLPLN
IMAIVVFILKMKVKKPAVVYMLHLATADVLFVSVLPFKISYYFSGSDWQFGSELCRFVTA
AFYCNMYASILLMTVISIDRFLAVVYPMQSLSWRTLGRASFTCLAIWALAIAGVVPLLLK
EQTIQVPGLNITTCHDVLNETLLEGYYAYYFSAFSAVFFFVPLIISTVCYVSIIRCLSSS
AVANRSKKSRALFLSAAVFCIFIICFGPTNVLLIAHYSFLSHTSTTEAAYFAYLLCVCVS
SISCCIDPLIYYYASSECQRYVYSILCCKESSDPSSYNSSGQLMASKMDTCSSNLNNSIY
KKLLT
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o10644723
2Galpha-q_Homo sapiensGq/1110644723
3Galpha-13_Homo sapiensG12/1310644723
4Galpha-i2_Homo sapiensGi/o10644723
5Galpha-z_Homo sapiensGi/o10644723
6Galpha-12_Homo sapiensG12/1310644723
7Galpha-i3_Homo sapiensGi/o10644723
8Galpha-14_Homo sapiensGq/1110644723
9Galpha-11_Homo sapiensGq/1110644723
10Galpha-o_Homo sapiensGi/o10644723
11Galpha-15_Homo sapiensGq/1110644723
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level