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Description Entry page for GPCR - 'PROTEINASE-ACTIVATED RECEPTORS_PAR4_Homo sapiens'
ClassCLASS A
FamilyPROTEINASE-ACTIVATED RECEPTORS
Sub-FamilyPAR4
Cross References:
References
UniProtQ96RI0 | O76067 | Q6DK42
EMBLAF080214 | AF055917 | AY431102 | AF384819 | BC074782
InterProIPR000276 | IPR017452 | IPR003944 | IPR003912
PRODOM
GENEID9002
MIM602779
PRINTSPR00237 | PR01428 | PR01430
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NamePROTEINASE-ACTIVATED RECEPTORS_PAR4_Homo sapiens
DescriptionRecName: Full=Proteinase-activated receptor 4; Short=PAR-4;AltName: Full=Thrombin receptor-like 3;AltName: Full=Coagulation factor II receptor-like 3;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneF2RL3 | PAR
FunctionReceptor for activated thrombin or trypsin coupled to Gs proteins that stimulate phosphoinositide hydrolysis
Fragment0
Sequence
MWGRLLLWPLVLGFSLSGGTQTPSVYDESGSTGGGDDSTPSILPAPRGYPGQVCANDSDT
LELPDSSRALLLGWVPTRLVPALYGLVLVVGLPANGLALWVLATQAPRLPSTMLLMNLAA
ADLLLALALPPRIAYHLRGQRWPFGEAACRLATAALYGHMYGSVLLLAAVSLDRYLALVH
PLRARALRGRRLALGLCMAAWLMAAALALPLTLQRQTFRLARSDRVLCHDALPLDAQASH
WQPAFTCLALLGCFLPLLAMLLCYGATLHTLAASGRRYGHALRLTAVVLASAVAFFVPSN
LLLLLHYSDPSPSAWGNLYGAYVPSLALSTLNSCVDPFIYYYVSAEFRDKVRAGLFQRSP
GDTVASKASAEGGSRGMGTHSSLLQ
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o15082510
2Galpha-q_Homo sapiensGq/1115082510
3Galpha-i2_Homo sapiensGi/o15082510
4Galpha-z_Homo sapiensGi/o15082510
5Galpha-i3_Homo sapiensGi/o15082510
6Galpha-11_Homo sapiensGq/1115082510
7Galpha-14_Homo sapiensGq/1115082510
8Galpha-o_Homo sapiensGi/o15082510
9Galpha-15_Homo sapiensGq/1115082510
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level