| Description |
Entry page for GPCR - 'CHEMOKINE RECEPTORS_CCR5_Homo sapiens'
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Cross References: |
| References |
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Details: |
| Details |
| Name | CHEMOKINE RECEPTORS_CCR5_Homo sapiens |
| Description | RecName: Full=C-C chemokine receptor type 5; Short=C-C CKR-5; Short=CC-CKR-5; Short=CCR-5; Short=CCR5;AltName: Full=HIV-1 fusion coreceptor;AltName: Full=CHEMR13;AltName: CD_antigen=CD195 |
| Species | Homo sapiens |
| Common Name | Human |
| NCBI Taxonomy | 9606 |
| Gene | CCR5 | CMKBR |
| Function | Receptor for a number of inflammatory CC-chemokiness including MIP-1-alpha, MIP-1-beta and RANTES and subsequentlys transduces a signal by increasing the intracellular calcium ions level |
| Fragment | 0 |
| Sequence | MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR
LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII
LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS
HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI
MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV
GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
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Interacting with G-proteins: |
| G-proteins |
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| GPCR, G-protein, Effector interaction |
Visualizaton of GPCR, G-protein, Effector interaction at protein level
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