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Description Entry page for G-protein - 'Galpha-15_Homo sapiens'
ClassGalpha
FamilyGq/11
Sub-FamilyGalpha-15/16
TypeGalpha-15
Cross References:
References
UniProtP30679 | O75247
EMBLM63904 | AF493904 | AC005264 | AC005262 | BC013585
InterProIPR001019 | IPR000654
PRODOMPD000281
GENEID2769
MIM139314
PRINTSPR00318 | PR00442
PFAMPF00503
Details:
Details
NameGalpha-15_Homo sapiens
DescriptionRecName: Full=Guanine nucleotide-binding protein subunit alpha-15; Short=G-protein subunit alpha-15; Short=G alpha-15;AltName: Full=Guanine nucleotide-binding protein subunit alpha-16; Short=G-protein subunit alpha-16; Short=G alpha-16
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGNA15 | GNA1
FunctionGuanine nucleotide-binding proteins (G proteins) ares involved as modulators or transducers in various transmembranes signaling systems
Fragment0
Sequence
MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK
QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD
PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ
DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ
CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG
PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR
DSVLARYLDEINLL
Effectors:
Effectors
NoNameRegulationPubMed
1Phospholipase C beta 1-Homo sapiensStimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
2GRK6-Homo sapiensStimulation14654303
3Phospholipase C beta 4-Homo sapiensStimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
4Phospholipase C beta 2-Homo sapiensStimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
5TPR repeat protein 1-Homo sapiensG16a co-expression enhances TPR1 interaction with Ras16182515 | 12748287
6Phospholipase C beta 3-Homo sapiensStimulation of PLC-beta catalytic activity15251227 | 16182515 | 11015615
Interacton with GPCRs:
Coupling with GPCRs
NoNameCouplingPubMed