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Description Entry page for GPCR - 'GABAb RECEPTORS_GABAb1_Homo sapiens'
ClassCLASS C
FamilyGABAb RECEPTORS
Sub-FamilyGABAb1
Cross References:
References
UniProtQ9UBS5 | B0UXY7 | O95375 | O95468 | O95975 | O96022 | Q86W60 | Q9UQQ0
EMBLAJ225028 | AJ225029 | AJ012185 | AJ012186 | AF099148 | Y11044 | AJ012187 | AJ010170 | AJ010171 | AJ010172 | AJ010173 | AJ010174 | AJ010175 | AJ010176 | AJ010177 | AJ010178 | AJ010179 | AJ010180 | AJ010181 | AJ010182 | AJ010183 | AJ010184 | AJ010185 | AJ010186 | AJ010187 | AJ010188 | AJ010189 | AJ010190 | AJ010191 | AJ012288 | AL031983 | AL031983 | CR388210 | BC042598 | BC050532
InterProIPR001828 | IPR016060 | IPR017978 | IPR017979 | IPR002455 | IPR002456 | IPR000436
PRODOM
GENEID2550
MIM603540
PRINTSPR01177 | PR01176
PFAMPF00003 | PF01094 | PF00084
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameGABAb RECEPTORS_GABAb1_Homo sapiens
DescriptionRecName: Full=Gamma-aminobutyric acid type B receptor subunit 1; Short=GABA-B receptor 1; Short=GABA-B-R1; Short=Gb1;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGABBR1 | GPRC3
FunctionReceptor for GABA
Fragment0
Sequence
MLLLLLLAPLFLRPPGAGGAQTPNATSEGCQIIHPPWEGGIRYRGLTRDQVKAINFLPVD
YEIEYVCRGEREVVGPKVRKCLANGSWTDMDTPSRCVRICSKSYLTLENGKVFLTGGDLP
ALDGARVDFRCDPDFHLVGSSRSICSQGQWSTPKPHCQVNRTPHSERRAVYIGALFPMSG
GWPGGQACQPAVEMALEDVNSRRDILPDYELKLIHHDSKCDPGQATKYLYELLYNDPIKI
ILMPGCSSVSTLVAEAARMWNLIVLSYGSSSPALSNRQRFPTFFRTHPSATLHNPTRVKL
FEKWGWKKIATIQQTTEVFTSTLDDLEERVKEAGIEITFRQSFFSDPAVPVKNLKRQDAR
IIVGLFYETEARKVFCEVYKERLFGKKYVWFLIGWYADNWFKIYDPSINCTVDEMTEAVE
GHITTEIVMLNPANTRSISNMTSQEFVEKLTKRLKRHPEETGGFQEAPLAYDAIWALALA
LNKTSGGGGRSGVRLEDFNYNNQTITDQIYRAMNSSSFEGVSGHVVFDASGSRMAWTLIE
QLQGGSYKKIGYYDSTKDDLSWSKTDKWIGGSPPADQTLVIKTFRFLSQKLFISVSVLSS
LGIVLAVVCLSFNIYNSHVRYIQNSQPNLNNLTAVGCSLALAAVFPLGLDGYHIGRNQFP
FVCQARLWLLGLGFSLGYGSMFTKIWWVHTVFTKKEEKKEWRKTLEPWKLYATVGLLVGM
DVLTLAIWQIVDPLHRTIETFAKEEPKEDIDVSILPQLEHCSSRKMNTWLGIFYGYKGLL
LLLGIFLAYETKSVSTEKINDHRAVGMAIYNVAVLCLITAPVTMILSSQQDAAFAFASLA
IVFSSYITLVVLFVPKMRRLITRGEWQSEAQDTMKTGSSTNNNEEEKSRLLEKENRELEK
IIAEKEERVSELRHQLQSRQQLRSRRHPPTPPEPSGGLPRGPPEPPDRLSCDGSRVHLLY
K
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o9872315
2Galpha-i3_Homo sapiensGi/o9872315
3Galpha-i2_Homo sapiensGi/o9872315
4Galpha-o_Homo sapiensGi/o9872315
5Galpha-z_Homo sapiensGi/o9872315
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level