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Description Entry page for GPCR - 'GABAb RECEPTORS_GABAb2_Homo sapiens'
ClassCLASS C
FamilyGABAb RECEPTORS
Sub-FamilyGABAb2
Cross References:
References
UniProtO75899 | O75974 | O75975 | Q5VXZ2 | Q8WX04 | Q9P1R2 | Q9UNR1 | Q9UNS9
EMBLAJ012188 | AF069755 | AF099033 | AF056085 | AF095784 | AF074483 | AL445495 | AL353782 | AL356282 | AL591502 | AL353782 | AL356282 | AL445495 | AL591502 | AL356282 | AL353782 | AL445495 | AL591502 | AL591502 | AL353782 | AL356282 | AL445495 | BC035071
InterProIPR001828 | IPR000337 | IPR017978 | IPR017979 | IPR002455 | IPR002457
PRODOM
GENEID9568
MIM607340
PRINTSPR01178 | PR01176 | PR00248
PFAMPF00003 | PF01094
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameGABAb RECEPTORS_GABAb2_Homo sapiens
DescriptionRecName: Full=Gamma-aminobutyric acid type B receptor subunit 2; Short=GABA-B receptor 2; Short=GABA-B-R2; Short=GABABR2; Short=Gb2;AltName: Full=G-protein coupled receptor 51;AltName: Full=HG20;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGABBR2 | GPR51,GPRC3
FunctionReceptor for GABA
Fragment0
Sequence
MASPRSSGQPGPPPPPPPPPARLLLLLLLPLLLPLAPGAWGWARGAPRPPPSSPPLSIMG
LMPLTKEVAKGSIGRGVLPAVELAIEQIRNESLLRPYFLDLRLYDTECDNAKGLKAFYDA
IKYGPNHLMVFGGVCPSVTSIIAESLQGWNLVQLSFAATTPVLADKKKYPYFFRTVPSDN
AVNPAILKLLKHYQWKRVGTLTQDVQRFSEVRNDLTGVLYGEDIEISDTESFSNDPCTSV
KKLKGNDVRIILGQFDQNMAAKVFCCAYEENMYGSKYQWIIPGWYEPSWWEQVHTEANSS
RCLRKNLLAAMEGYIGVDFEPLSSKQIKTISGKTPQQYEREYNNKRSGVGPSKFHGYAYD
GIWVIAKTLQRAMETLHASSRHQRIQDFNYTDHTLGRIILNAMNETNFFGVTGQVVFRNG
ERMGTIKFTQFQDSREVKVGEYNAVADTLEIINDTIRFQGSEPPKDKTIILEQLRKISLP
LYSILSALTILGMIMASAFLFFNIKNRNQKLIKMSSPYMNNLIILGGMLSYASIFLFGLD
GSFVSEKTFETLCTVRTWILTVGYTTAFGAMFAKTWRVHAIFKNVKMKKKIIKDQKLLVI
VGGMLLIDLCILICWQAVDPLRRTVEKYSMEPDPAGRDISIRPLLEHCENTHMTIWLGIV
YAYKGLLMLFGCFLAWETRNVSIPALNDSKYIGMSVYNVGIMCIIGAAVSFLTRDQPNVQ
FCIVALVIIFCSTITLCLVFVPKLITLRTNPDAATQNRRFQFTQNQKKEDSKTSTSVTSV
NQASTSRLEGLQSENHRLRMKITELDKDLEEVTMQLQDTPEKTTYIKQNHYQELNDILNL
GNFTESTDGGKAILKNHLDQNPQLQWNTTEPSRTCKDPIEDINSPEHIQRRLSLQLPILH
HAYLPSIGGVDASCVSPCVSPTASPRHRHVPPSFRVMVSGL
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o9872315
2Galpha-i3_Homo sapiensGi/o9872315
3Galpha-i2_Homo sapiensGi/o9872315
4Galpha-o_Homo sapiensGi/o9872315
5Galpha-z_Homo sapiensGi/o9872315
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level