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Description Entry page for GPCR - 'METABOTROPIC GLUTAMATE RECEPTORS_MGLU2_Homo sapiens'
ClassCLASS C
FamilyMETABOTROPIC GLUTAMATE RECEPTORS
Sub-FamilyMGLU2
Cross References:
References
UniProtQ14416 | Q14CU5 | Q52MC6 | Q9H3N6
EMBLL35318 | AB045011 | AY999299 | BC113615 | BC113619
InterProIPR001828 | IPR000337 | IPR017978 | IPR017979 | IPR000162 | IPR001458 | IPR011500
PRODOM
GENEID2912
MIM604099
PRINTSPR00248 | PR01052 | PR00593
PFAMPF00003 | PF01094 | PF07562
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameMETABOTROPIC GLUTAMATE RECEPTORS_MGLU2_Homo sapiens
DescriptionRecName: Full=Metabotropic glutamate receptor 2; Short=mGluR2;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGRM2 | GPRC1B,MGLUR
FunctionReceptor for glutamate
Fragment0
Sequence
MGSLLALLALLLLWGAVAEGPAKKVLTLEGDLVLGGLFPVHQKGGPAEDCGPVNEHRGIQ
RLEAMLFALDRINRDPHLLPGVRLGAHILDSCSKDTHALEQALDFVRASLSRGADGSRHI
CPDGSYATHGDAPTAITGVIGGSYSDVSIQVANLLRLFQIPQISYASTSAKLSDKSRYDY
FARTVPPDFFQAKAMAEILRFFNWTYVSTVASEGDYGETGIEAFELEARARNICVATSEK
VGRAMSRAAFEGVVRALLQKPSARVAVLFTRSEDARELLAASQRLNASFTWVASDGWGAL
ESVVAGSEGAAEGAITIELASYPISDFASYFQSLDPWNNSRNPWFREFWEQRFRCSFRQR
DCAAHSLRAVPFEQESKIMFVVNAVYAMAHALHNMHRALCPNTTRLCDAMRPVNGRRLYK
DFVLNVKFDAPFRPADTHNEVRFDRFGDGIGRYNIFTYLRAGSGRYRYQKVGYWAEGLTL
DTSLIPWASPSAGPLPASRCSEPCLQNEVKSVQPGEVCCWLCIPCQPYEYRLDEFTCADC
GLGYWPNASLTGCFELPQEYIRWGDAWAVGPVTIACLGALATLFVLGVFVRHNATPVVKA
SGRELCYILLGGVFLCYCMTFIFIAKPSTAVCTLRRLGLGTAFSVCYSALLTKTNRIARI
FGGAREGAQRPRFISPASQVAICLALISGQLLIVVAWLVVEAPGTGKETAPERREVVTLR
CNHRDASMLGSLAYNVLLIALCTLYAFKTRKCPENFNEAKFIGFTMYTTCIIWLAFLPIF
YVTSSDYRVQTTTMCVSVSLSGSVVLGCLFAPKLHIILFQPQKNVVSHRAPTSRFGSAAA
RASSSLGQGSGSQFVPTVCNGREVVDSTTSSL
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o1309649
2Galpha-i3_Homo sapiensGi/o1309649
3Galpha-i2_Homo sapiensGi/o1309649
4Galpha-o_Homo sapiensGi/o1309649
5Galpha-z_Homo sapiensGi/o1309649
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level