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Description Entry page for GPCR - 'METABOTROPIC GLUTAMATE RECEPTORS_MGLU4_Homo sapiens'
ClassCLASS C
FamilyMETABOTROPIC GLUTAMATE RECEPTORS
Sub-FamilyMGLU4
Cross References:
References
UniProtQ14833 | Q5SZ84
EMBLX80818 | U92457 | AL590403
InterProIPR001828 | IPR000337 | IPR017978 | IPR017979 | IPR000162 | IPR001786 | IPR011500
PRODOM
GENEID2914
MIM604100
PRINTSPR00248 | PR01054 | PR00593
PFAMPF00003 | PF01094 | PF07562
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameMETABOTROPIC GLUTAMATE RECEPTORS_MGLU4_Homo sapiens
DescriptionRecName: Full=Metabotropic glutamate receptor 4; Short=mGluR4;Flags: Precursor
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneGRM4 | GPRC1D,MGLUR
FunctionReceptor for glutamate
Fragment0
Sequence
MPGKRGLGWWWARLPLCLLLSLYGPWMPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKPCGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTVASEGSYGESGVEAFIQ
KSREDGGVCIAQSVKIPREPKAGEFDKIIRRLLETSNARAVIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKIAPVLHLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHVKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNDSAEYKVIGSWTDHLHLRIERMHWPGSGQQLPRSICSLPCQPGERKKTVKGMPCCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTGCRPIPIIKLEWGSPWAVLPLFLAVVGIA
ATLFVVITFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFSLISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLEAPALAT
KQTYVTYTNHAI
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o1309649
2Galpha-i3_Homo sapiensGi/o1309649
3Galpha-i2_Homo sapiensGi/o1309649
4Galpha-o_Homo sapiensGi/o1309649
5Galpha-z_Homo sapiensGi/o1309649
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level