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Description Entry page for GPCR - 'P2Y RECEPTORS_P2Y12_Homo sapiens'
ClassCLASS A
FamilyP2Y RECEPTORS
Sub-FamilyP2Y12
Cross References:
References
UniProtQ9H244 | Q546J7
EMBLAF313449 | AF321815 | AB052684 | AF310685 | AJ320495 | AB083596 | AY136754 | BC017898
InterProIPR000276 | IPR017452 | IPR002286 | IPR005394
PRODOM
GENEID64805
MIM600515 | 609821
PRINTSPR00237 | PR01569 | PR01157
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NameP2Y RECEPTORS_P2Y12_Homo sapiens
DescriptionRecName: Full=P2Y purinoceptor 12; Short=P2Y12;AltName: Full=P2Y12 platelet ADP receptor; Short=P2Y(ADP);AltName: Full=ADP-glucose receptor; Short=ADPG-R;AltName: Full=P2Y(AC);AltName: Full=P2Y(cyc);AltName: Full=P2T(AC);AltName: Full=SP1999
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GeneP2RY12 | HORK
FunctionReceptor for ADP and ATP coupled to G-proteins thats inhibit the adenylyl cyclase second messenger system
Fragment0
Sequence
MQAVDNLTSAPGNTSLCTRDYKITQVLFPLLYTVLFFVGLITNGLAMRIFFQIRSKSNFI
IFLKNTVISDLLMILTFPFKILSDAKLGTGPLRTFVCQVTSVIFYFTMYISISFLGLITI
DRYQKTTRPFKTSNPKNLLGAKILSVVIWAFMFLLSLPNMILTNRQPRDKNVKKCSFLKS
EFGLVWHEIVNYICQVIFWINFLIVIVCYTLITKELYRSYVRTRGVGKVPRKKVNVKVFI
IIAVFFICFVPFHFARIPYTLSQTRDVFDCTAENTLFYVKESTLWLTSLNACLDPFIYFF
LCKSFRNSLISMLKCPNSATSLSQDNRKKEQDGGDPNEETPM
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o11196645
2Galpha-i3_Homo sapiensGi/o11196645
3Galpha-i2_Homo sapiensGi/o11196645
4Galpha-o_Homo sapiensGi/o11196645
5Galpha-z_Homo sapiensGi/o11196645
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level