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Description Entry page for GPCR - 'PLATELET-ACTIVATING FACTOR RECEPTORS_PAF_Homo sapiens'
ClassCLASS A
FamilyPLATELET-ACTIVATING FACTOR RECEPTORS
Sub-FamilyPAF
Cross References:
References
UniProtP25105 | A3KMC8 | A8K2H5
EMBLM80436 | D10202 | M76674 | M88177 | S52624 | L07334 | S56396 | AY275466 | BT009801 | AK290240 | CH471059 | BC013816 | BC063000
InterProIPR000276 | IPR017452 | IPR002282
PRODOM
GENEID5724
MIM173393
PRINTSPR00237 | PR01153
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NamePLATELET-ACTIVATING FACTOR RECEPTORS_PAF_Homo sapiens
DescriptionRecName: Full=Platelet-activating factor receptor; Short=PAF-R
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GenePTAFR | PAF
FunctionReceptor for platelet activating factor, a chemotactics phospholipid mediator that possesses potent inflammatory, smooth-s muscle contractile and hypotensive activity
Fragment0
Sequence
MEPHDSSHMDSEFRYTLFPIVYSIIFVLGVIANGYVLWVFARLYPCKKFNEIKIFMVNLT
MADMLFLITLPLWIVYYQNQGNWILPKFLCNVAGCLFFINTYCSVAFLGVITYNRFQAVT
RPIKTAQANTRKRGISLSLVIWVAIVGAASYFLILDSTNTVPDSAGSGNVTRCFEHYEKG
SVPVLIIHIFIVFSFFLVFLIILFCNLVIIRTLLMQPVQQQRNAEVKRRALWMVCTVLAV
FIICFVPHHVVQLPWTLAELGFQDSKFHQAINDAHQVTLCLLSTNCVLDPVIYCFLTKKF
RKHLTEKFYSMRSSRKCSRATTDTVTEVVVPFNQIPGNSLKN
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o7876256
2Galpha-q_Homo sapiensGq/117876256
3Galpha-i2_Homo sapiensGi/o7876256
4Galpha-z_Homo sapiensGi/o7876256
5Galpha-i3_Homo sapiensGi/o7876256
6Galpha-11_Homo sapiensGq/117876256
7Galpha-14_Homo sapiensGq/117876256
8Galpha-o_Homo sapiensGi/o7876256
9Galpha-15_Homo sapiensGq/117876256
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level