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Description Entry page for GPCR - 'PROSTANOID RECEPTORS_E3_Homo sapiens'
ClassCLASS A
FamilyPROSTANOID RECEPTORS
Sub-FamilyE3
Cross References:
References
UniProtP43115 | B0AZN4 | B5BUP5 | O00326 | Q12943 | Q12944 | Q12945 | Q16546
EMBLS69200 | L27488 | L27489 | L27490 | X83857 | X83858 | X83859 | X83860 | X83861 | X83862 | X83863 | L26976 | S69326 | L32660 | L32661 | L32662 | D38297 | D38298 | D38299 | D38300 | D38301 | U13214 | U13215 | U13216 | U13217 | U13218 | D86096 | D86098 | AY429108 | AK315825 | AB451481 | AL031429 | AL031429 | AL031429 | AL158087 | AL158087 | AL031429 | AL031429 | CH471059 | BC024229
InterProIPR000276 | IPR001481 | IPR017452 | IPR008365 | IPR001244 | IPR000265
PRODOM
GENEID5733
MIM176806
PRINTSPR00237 | PR00428 | PR01788 | PR00584 | PR00582
PFAMPF00001
Other GPCR resourcesGPCRDB | GPCR-OKB | GLIDA
Details:
Details
NamePROSTANOID RECEPTORS_E3_Homo sapiens
Description"RecName: Full=Prostaglandin E2 receptor EP3 subtype; Short=PGE receptor, EP3 subtype; Short=PGE2-R;AltName: Full=Prostanoid EP3 receptor;"
SpeciesHomo sapiens
Common NameHuman
NCBI Taxonomy9606
GenePTGER
FunctionReceptor for prostaglandin E2 (PGE2); the EP3 receptors may be involved in inhibition of gastric acid secretion,s modulation of neurotransmitter release in central and peripherals neurons, inhibition of sodium and water reabsorption in kidneys tubulus and contraction in uterine smooth muscle
Fragment0
Sequence
MKETRGYGGDAPFCTRLNHSYTGMWAPERSAEARGNLTRPPGSGEDCGSVSVAFPITMLL
TGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVVYLSKQRW
EHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRATRAVLLG
VWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASAFAFLGLL
ALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSVCWSPLLI
MMLKMIFNQTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLLRKILLRKFCQI
RYHTNNYASSSTSLPCQCSSTLMWSDHLER
Interacting with G-proteins:
G-proteins
NoNameCouplingPubMed
1Galpha-i1_Homo sapiensGi/o11095474
2Galpha-q_Homo sapiensGq/1111095474
3Galpha-i2_Homo sapiensGi/o11095474
4Galpha-s_Homo sapiens_1Gs11095474
5Galpha-z_Homo sapiensGi/o11095474
6Galpha-i3_Homo sapiensGi/o11095474
7Galpha-11_Homo sapiensGq/1111095474
8Galpha-14_Homo sapiensGq/1111095474
9Galpha-s_Homo sapiens_2Gs11095474
10Galpha-o_Homo sapiensGi/o11095474
11Galpha-15_Homo sapiensGq/1111095474
GPCR, G-protein, Effector interaction Visualizaton of GPCR, G-protein, Effector interaction at protein level